Search Results - "Zaucha, Jan"

Response to Rituximab Induction Is a Predictive Marker in B-Cell Post-Transplant Lymphoproliferative Disorder and Allows Successful Stratification Into Rituximab or R-CHOP Consolidation in an International, Prospective, Multicenter Phase II Trial by Trappe, Ralf U, Dierickx, Daan, Zimmermann, Heiner, Morschhauser, Franck, Mollee, Peter, Zaucha, Jan M, Dreyling, Martin H, Dührsen, Ulrich, Reinke, Petra, Verhoef, Gregor, Subklewe, Marion, Hüttmann, Andreas, Tousseyn, Thomas, Salles, Gilles, Kliem, Volker, Hauser, Ingeborg A, Tarella, Corrado, Van Den Neste, Eric, Gheysens, Olivier, Anagnostopoulos, Ioannis, Leblond, Veronique, Riess, Hanno, Choquet, Sylvain

“…Purpose The Sequential Treatment of CD20-Positive Posttransplant Lymphoproliferative Disorder (PTLD-1) trial ( ClinicalTrials.gov identifier, NCT01458548)…”
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Detection of epistasis between ACTN3 and SNAP-25 with an insight towards gymnastic aptitude identification by Płóciennik, Łukasz Andrzej, Zaucha, Jan, Zaucha, Jan Maciej, Łukaszuk, Krzysztof, Jóźwicki, Marek, Płóciennik, Magdalena, Cięszczyk, Paweł

“…In this study, we performed an analysis of the impact of performance enhancing polymorphisms (PEPs) on gymnastic aptitude while considering epistatic effects…”
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The predictive role of interim positron emission tomography for Hodgkin lymphoma treatment outcome is confirmed using the interpretation criteria of the Deauville five-point scale by Gallamini, Andrea, Barrington, Sally F, Biggi, Alberto, Chauvie, Stephane, Kostakoglu, Lale, Gregianin, Michele, Meignan, Michel, Mikhaeel, George N, Loft, Annika, Zaucha, Jan M, Seymour, John F, Hofman, Michael S, Rigacci, Luigi, Pulsoni, Alessandro, Coleman, Morton, Dann, Eldad J, Trentin, Livio, Casasnovas, Olivier, Rusconi, Chiara, Brice, Pauline, Bolis, Silvia, Viviani, Simonetta, Salvi, Flavia, Luminari, Stefano, Hutchings, Martin

“…A retrospective, international, multicenter study was undertaken to assess: (i) the prognostic role of 'interim' positron emission tomography performed during…”
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Author Correction: Edgetic perturbation signatures represent known and novel cancer biomarkers by Kataka, Evans, Zaucha, Jan, Frishman, Goar, Ruepp, Andreas, Frishman, Dmitrij

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Ribosomal Protein L5 and L11 Mutations Are Associated with Cleft Palate and Abnormal Thumbs in Diamond-Blackfan Anemia Patients by Gazda, Hanna T., Sheen, Mee Rie, Vlachos, Adrianna, Choesmel, Valerie, O'Donohue, Marie-Françoise, Schneider, Hal, Darras, Natasha, Hasman, Catherine, Sieff, Colin A., Newburger, Peter E., Ball, Sarah E., Niewiadomska, Edyta, Matysiak, Michal, Zaucha, Jan M., Glader, Bertil, Niemeyer, Charlotte, Meerpohl, Joerg J., Atsidaftos, Eva, Lipton, Jeffrey M., Gleizes, Pierre-Emmanuel, Beggs, Alan H.

“…Diamond-Blackfan anemia (DBA), a congenital bone-marrow-failure syndrome, is characterized by red blood cell aplasia, macrocytic anemia, clinical…”
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Immune escape of B-cell lymphoblastic leukemic cells through a lineage switch to acute myeloid leukemia by Bełdzińska-Gądek, Karolina, Zarzycka, Ewa, Pastuszak, Krzysztof, Borman, Katarzyna, Lewandowski, Krzysztof, Zaucha, Jan M, Prejzner, Witold

“…Acute leukemia (AL) with a lineage switch (LS) is associated with poor prognosis. The predisposing factors of LS are unknown, apart from rearrangements that…”
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Transcriptomic Approaches in Studies on and Applications of Chimeric Antigen Receptor T Cells by Pierzynowska, Karolina, Gaffke, Lidia, Zaucha, Jan M, Węgrzyn, Grzegorz

“…Chimeric antigen receptor T (CAR-T) cells are specifically modified T cells which bear recombinant receptors, present at the cell surface and devoted to detect…”
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Effective treatment of Clostridioides difficile infection improves survival and affects graft-versus-host disease: a multicenter study by the Polish Adult Leukemia Group by Piekarska, Agnieszka, Sadowska-Klasa, Alicja, Mensah-Glanowska, Patrycja, Sobczyk-Kruszelnicka, Małgorzata, Drozd-Sokołowska, Joanna, Waszczuk-Gajda, Anna, Kujawska, Joanna, Wilk, Mateusz, Tomaszewska, Agnieszka, Zaucha, Jan M., Giebel, Sebastian, Gil, Lidia

“…Clostridioides difficile infection (CDI) is the most common cause of infectious diarrhea after allogeneic hematopoietic cell transplantation (allo-HCT). The…”
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Edgetic perturbation signatures represent known and novel cancer biomarkers by Kataka, Evans, Zaucha, Jan, Frishman, Goar, Ruepp, Andreas, Frishman, Dmitrij

“…Isoform switching is a recently characterized hallmark of cancer, and often translates to the loss or gain of domains mediating protein interactions and thus,…”
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The management of gynecological complications in long-term survivors after allogeneic hematopoietic cell transplantation—a single-center real-life experience by Klasa, Łukasz, Sadowska-Klasa, Alicja, Piekarska, Agnieszka, Wydra, Dariusz, Zaucha, Jan Maciej

“…In everyday gynecological practice, there is an unmet need to manage survivors after allogeneic hematopoietic cell transplantation (allo-HCT). The major…”
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The Acquisition of Complement-Dependent Cytotoxicity by the Type II Anti-CD20 Therapeutic Antibody Obinutuzumab by Kuźniewska, Alicja, Majeranowski, Alan, Henry, Sara, Kowalska, Daria, Stasiłojć, Grzegorz, Urban, Aleksandra, Zaucha, Jan M, Okrój, Marcin

“…Rituximab, a prototypic anti-CD20 mAb, and the third-generation anti-CD20 mAb obinutuzumab differ in their ability to activate the complement system. According…”
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The SUPERFAMILY 1.75 database in 2014: a doubling of data by Oates, Matt E, Stahlhacke, Jonathan, Vavoulis, Dimitrios V, Smithers, Ben, Rackham, Owen J L, Sardar, Adam J, Zaucha, Jan, Thurlby, Natalie, Fang, Hai, Gough, Julian

“…We present updates to the SUPERFAMILY 1.75 (http://supfam.org) online resource and protein sequence collection. The hidden Markov model library that provides…”
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Monitoring of the Complement System Status in Patients With B-Cell Malignancies Treated With Rituximab by Felberg, Anna, Taszner, Michał, Urban, Aleksandra, Majeranowski, Alan, Jaskuła, Kinga, Jurkiewicz, Aleksandra, Stasiłojć, Grzegorz, Blom, Anna M, Zaucha, Jan M, Okrój, Marcin

“…Rituximab is a pioneering anti-CD20 monoclonal antibody that became the first-line drug used in immunotherapy of B-cell malignancies over the last twenty…”
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A phase 3, randomized study of ofatumumab combined with bendamustine in rituximab‐refractory iNHL (COMPLEMENT A + B study) by Rummel, Mathias J., Janssens, Ann, MacDonald, David, Keating, Mary‐Margaret, Zaucha, Jan M., Davis, Jaclyn, Lasher, Janet, Babanrao Pisal, Chaitali, Izquierdo, Miguel, Friedberg, Jonathan W.

“…Summary The standard of care for indolent non‐Hodgkin lymphoma (iNHL) is rituximab, an anti‐CD20 antibody, with/without chemotherapy. However, multiple…”
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Polyclonal immunoglobulin recovery in patients with newly diagnosed myeloma receiving maintenance therapy after autologous haematopoietic stem cell transplantation with either carfilzomib, lenalidomide and dexamethasone or lenalidomide alone: Subanalysis of the randomized phase 3 ATLAS trial by Kubicki, Tadeusz, Dytfeld, Dominik, Wróbel, Tomasz, Jamroziak, Krzysztof, Robak, Paweł, Czyż, Jarosław, Tyczyńska, Agata, Druzd‐Sitek, Agnieszka, Giannopoulos, Krzysztof, Szczepaniak, Tomasz, Łojko‐Dankowska, Anna, Matuszak, Magdalena, Gil, Lidia, Puła, Bartosz, Rybka, Justyna, Majcherek, Maciej, Usnarska‐Zubkiewicz, Lidia, Szukalski, Łukasz, Zaucha, Jan Maciej, Mikulski, Damian, Czabak, Olga, Lahoud, Oscar B., Stefka, Andrew, Derman, Benjamin A., Jakubowiak, Andrzej J.

“…Summary Previous studies suggest that postautologous stem cell transplant (ASCT) recovery of polyclonal immunoglobulin from immunoparesis in patients with…”
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In Silico Designed Gain-of-Function Variants of Complement C2 Support Cytocidal Activity of Anticancer Monoclonal Antibodies by Urban, Aleksandra, Majeranowski, Alan, Stasiłojć, Grzegorz, Koszałka, Patrycja, Felberg, Anna, Taszner, Michał, Zaucha, Jan M, Okrój, Marcin

“…The molecular target for the classical complement pathway (CP) is defined by surface-bound immunoglobulins. Therefore, numerous anticancer monoclonal…”
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The Real-World Evidence on the Fragility and Its Impact on the Choice of Treatment Regimen in Newly Diagnosed Patients with Multiple Myeloma over 75 Years of Age by Tyczyńska, Agata, Krzempek, Marcela Krzysława, Cortez, Alexander Jorge, Jurczyszyn, Artur, Godlewska, Katarzyna, Ciepłuch, Hanna, Subocz, Edyta, Hałka, Janusz, Kulikowska de Nałęcz, Anna, Wiśniewska, Anna, Świderska, Alina, Waszczuk-Gajda, Anna, Drozd-Sokołowska, Joanna, Guzicka-Kazimierczak, Renata, Wiśniewski, Kamil, Porowska, Agnieszka, Knopińska-Posłuszny, Wanda, Kłoczko, Janusz, Rzepecki, Piotr, Woszczyk, Dariusz, Symonowicz, Hanna, Basak, Grzegorz Władysław, Zdziarska, Barbara, Jamroziak, Krzysztof, Zaucha, Jan M

“…Fragility scales are intended to help in therapeutic decisions. Here, we asked if the fragility assessment in MM patients ≥ 75 years old qualified for…”
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Current and Future Perspectives for Chimeric Antigen Receptor T Cells Development in Poland by Ślebioda, Tomasz J, Stanisławowski, Marcin, Kaszubowska, Lucyna, Zaucha, Jan M, Żmijewski, Michał A

“…Chimeric antigen receptor T (CAR-T) cells are genetically modified autologous T cells that have revolutionized the treatment of relapsing and refractory…”
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Secondary chronic myeloid leukemia in a patient with CALR and ASXL1-mutated primary myelofibrosis by Sobieralski, Patryk, Bieniaszewska, Maria, Leszczyńska, Aleksandra, Żuk, Monika, Wasąg, Bartosz, Zaucha, Jan Maciej

“…Development of secondary CML has only been casually described, with few reports attempting to analyze and explain the mechanisms behind this phenomenon…”
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Hypothesis-free phenotype prediction within a genetics-first framework by Lu, Chang, Zaucha, Jan, Gam, Rihab, Fang, Hai, Ben Smithers, Oates, Matt E., Bernabe-Rubio, Miguel, Williams, James, Zelenka, Natalie, Pandurangan, Arun Prasad, Tandon, Himani, Shihab, Hashem, Kalaivani, Raju, Sung, Minkyung, Sardar, Adam J., Tzovoras, Bastian Greshake, Danovi, Davide, Gough, Julian

“…Cohort-wide sequencing studies have revealed that the largest category of variants is those deemed ‘rare’, even for the subset located in coding regions (99%…”
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