Search Results - "Zatulovskiy, Evgeny"

On the Molecular Mechanisms Regulating Animal Cell Size Homeostasis by Zatulovskiy, Evgeny, Skotheim, Jan M.

“…Cell size is fundamental to cell physiology because it sets the scale of intracellular geometry, organelles, and biosynthetic processes. In animal cells, size…”
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Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division by Zatulovskiy, Evgeny, Zhang, Shuyuan, Berenson, Daniel F, Topacio, Benjamin R, Skotheim, Jan M

“…Cell size is fundamental to cell physiology. For example, cell size determines the spatial scale of organelles and intracellular transport and thereby affects…”
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A Precise Cdk Activity Threshold Determines Passage through the Restriction Point by Schwarz, Clayton, Johnson, Amy, Kõivomägi, Mardo, Zatulovskiy, Evgeny, Kravitz, Carolyn J., Doncic, Andreas, Skotheim, Jan M.

“…At the restriction point (R), mammalian cells irreversibly commit to divide. R has been viewed as a point in G1 that is passed when growth factor signaling…”
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Bleb-driven chemotaxis of Dictyostelium cells by Zatulovskiy, Evgeny, Tyson, Richard, Bretschneider, Till, Kay, Robert R

“…Blebs and F-actin-driven pseudopods are alternative ways of extending the leading edge of migrating cells. We show that Dictyostelium cells switch from using…”
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How blebs and pseudopods cooperate during chemotaxis by Tyson, Richard A., Zatulovskiy, Evgeny, Kay, Robert R., Bretschneider, Till

“…Two motors can drive extension of the leading edge of motile cells: actin polymerization and myosin-driven contraction of the cortex, producing fluid pressure…”
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Editorial: Cell size regulation: molecular mechanisms and physiological importance by Lengefeld, Jette, Zatulovskiy, Evgeny

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Delineation of proteome changes driven by cell size and growth rate by Zatulovskiy, Evgeny, Lanz, Michael C, Zhang, Shuyuan, McCarthy, Frank, Elias, Joshua E, Skotheim, Jan M

“…Increasing cell size drives changes to the proteome, which affects cell physiology. As cell size increases, some proteins become more concentrated while others…”
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The cell cycle inhibitor RB is diluted in G1 and contributes to controlling cell size in the mouse liver by Zhang, Shuyuan, Zatulovskiy, Evgeny, Arand, Julia, Sage, Julien, Skotheim, Jan M

“…Every type of cell in an animal maintains a specific size, which likely contributes to its ability to perform its physiological functions. While some cell size…”
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Serum depletion of holo-ceruloplasmin induced by silver ions in vivo reduces uptake of cisplatin by Zatulovskiy, Evgeny A., Skvortsov, Alexey N., Rusconi, Paolo, Ilyechova, Ekaterina Yu, Babich, Polina S., Tsymbalenko, Nadezhda V., Broggini, Massimo, Puchkova, Ludmila V.

“…There is an emerging link between extracellular copper concentration and the uptake of cisplatin mediated by copper transporter CTR1 in cell cultures and…”
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Mass spectrometry and biochemical analysis of RNA polymerase II: targeting by protein phosphatase-1 by Jerebtsova, Marina, Klotchenko, Sergei A, Artamonova, Tatiana O, Ammosova, Tatiana, Washington, Kareem, Egorov, Vladimir V, Shaldzhyan, Aram A, Sergeeva, Maria V, Zatulovskiy, Evgeny A, Temkina, Olga A, Petukhov, Mikhail G, Vasin, Andrei V, Khodorkovskii, Mikhail A, Orlov, Yuri N, Nekhai, Sergei

“…Transcription of eukaryotic genes is regulated by phosphorylation of serine residues of heptapeptide repeats of the carboxy-terminal domain (CTD) of RNA…”
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e2f1 gene is a new member of Wnt/β-catenin/Tcf-regulated genes by Abramova, Maria V., Zatulovskiy, Evgeny A., Svetlikova, Svetlana B., Kukushkin, Alexander N., Pospelov, Valery A.

“…HDAC inhibitors induce cell cycle arrest of E1A+Ras-transformed cells accompanied by e2f1 gene down-regulation and activation of Wnt pathway. Here we show that…”
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Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein’s C-Terminal Helix by Topacio, Benjamin R., Zatulovskiy, Evgeny, Cristea, Sandra, Xie, Shicong, Tambo, Carrie S., Rubin, Seth M., Sage, Julien, Kõivomägi, Mardo, Skotheim, Jan M.

“…The cyclin-dependent kinases Cdk4 and Cdk6 form complexes with D-type cyclins to drive cell proliferation. A well-known target of cyclin D-Cdk4,6 is the…”
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Increasing cell size remodels the proteome and promotes senescence by Lanz, Michael C, Zatulovskiy, Evgeny, Swaffer, Matthew P, Zhang, Lichao, Ilerten, Ilayda, Zhang, Shuyuan, You, Dong Shin, Marinov, Georgi, McAlpine, Patrick, Elias, Joshua E, Skotheim, Jan M

“…Cell size is tightly controlled in healthy tissues, but it is unclear how deviations in cell size affect cell physiology. To address this, we measured how the…”
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Constitutive expression of a fluorescent protein reports the size of live human cells by Berenson, Daniel F, Zatulovskiy, Evgeny, Xie, Shicong, Skotheim, Jan M

“…Cell size is important for cell physiology because it sets the geometric scale of organelles and biosynthesis. A number of methods exist to measure different…”
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Repellent and Attractant Guidance Cues Initiate Cell Migration by Distinct Rear-Driven and Front-Driven Cytoskeletal Mechanisms by Cramer, Louise P., Kay, Robert R., Zatulovskiy, Evgeny

“…Attractive and repulsive cell guidance is essential for animal life and important in disease. Cell migration toward attractants dominates studies [1–8], but…”
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Mitosis is swell by Zatulovskiy, Evgeny, Skotheim, Jan M

“…Cell volume and dry mass are typically correlated. However, in this issue, Zlotek-Zlotkiewicz et al. (2015. J. Cell Biol…”
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The G 1 -S transition is promoted by Rb degradation via the E3 ligase UBR5 by Zhang, Shuyuan, Valenzuela, Lucas Fuentes, Zatulovskiy, Evgeny, Mangiante, Lise, Curtis, Christina, Skotheim, Jan M

“…Mammalian cells make the decision to divide at the G -S transition in response to diverse signals impinging on the retinoblastoma protein Rb, a cell cycle…”
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The G1-S transition is promoted by Rb degradation via the E3 ligase UBR5 by Zhang, Shuyuan, Valenzuela, Lucas Fuentes, Zatulovskiy, Evgeny, Mangiante, Lise, Curtis, Christina, Skotheim, Jan M

“…Mammalian cells make the decision to divide at the G1-S transition in response to diverse signals impinging on the retinoblastoma protein Rb, a cell cycle…”
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Chemotactic Blebbing in Dictyostelium Cells by Zatulovskiy, Evgeny, Kay, Robert R

“…Many researchers use the social amoeba Dictyostelium discoideum as a model organism to study various aspects of the eukaryotic cell chemotaxis. Traditionally,…”
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Repellent and Attractant Guidance Cues Initiate Cell Migration by Distinct Rear-Driven and Front-Driven Cytoskeletal Mechanisms by Cramer, Louise P., Kay, Robert R., Zatulovskiy, Evgeny

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