Search Results - "Zasukhina, G. D"

Risk of Depression after Radiation by Zasukhina, G. D., Maximova, T. N.

“…Data from a number of authors on the risk of developing psychogenic disorders, mainly depression as the most severe pathology, after accidents at nuclear power…”
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Prospects for the Use of Thymoquinone (a Component of Nigella sativa) in the Prevention and Therapy of Neuropathologies by Zasukhina, G. D., Maksimova, T. N.

“…Black cumin and its component thymoquinone (TQ) are known as drugs with a wide range of pharmacological activities: immunomodulating, anti-inflammatory,…”
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MicroRNA: Role in Gene Regulation, Disease Prognosis, Radiotherapy, and the Activity of Radioprotectors by Saleeva, D. V., Raeva, N. F., Sviridova, D. A., Zasukhina, G. D.

“…MicroRNAs are small, highly conserved noncoding RNAs (containing about 20 nucleotides), involved in the regulation of gene activity on the post-transcriptional…”
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Prospects for using low-dose radiation in the complex therapy for COVID-19 by Saleeva, D. V., Zasukhina, G. D.

“…This review presents the literature data of new approaches for the treatment of COVID-19 with low doses of radiation (LDR). In addition, data on the use of LDR…”
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Long Noncoding RNAs in Radiation Response by Shulenina, L. V., Mikhailov, V. F., Zasukhina, G. D.

“…This review is devoted to various aspects of studying functions of long RNAs (lncRNAs) under radiation exposure. A hypothesis on the lncRNA origin, their…”
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The Сonnection between the Growth Dynamics of Transplanted Lewis Carcinoma in Mice and Changes in the Activity of Genes and Noncoding RNAs after Low-Dose Irradiation by Mikhailov, V. F., Saleeva, D. V., Shulenina, L. V., Raeva, N. F., Rozhdestvensky, L. M., Zasukhina, G. D.

“…The effect of low-dose radiation was studied on the growth dynamics of transfused Lewis carcinoma cells in female C57Bl/6 mice. Fourfold total fractionated…”
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Changes in the Activity of Genes Involved in the Regulation of Hematopoiesis during Tumorigenesis in Irradiated Mice by Saleeva, D. V., Mikhailov, V. F., Rozhdestvenskii, L. M., Shulenina, L. V., Raeva, N. F., Zasukhina, G. D.

“…We used 183 F1 CBA×C57Bl hybrid mice to study the delayed effects of low-power long-term γ-irradiation at a dose of 12.6 Gy (10 mGy/min) 8 and 10 months after…”
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Protection of radiosensitive human cells against the action of heavy metals by antimutagens and adapting factors: Assotiation with genetic and protein polymorphisms by Vasilyeva, I. M, Shagirova, Zh. M, Sinelshikova, T. A, Mavletova, D. A, Kuzmina, N. S, Zasukhina, G. D

“…Cells of a diploid line obtained from embryos with the Down's syndrome, known to be unable to repair gamma-induced DNA damage, were treated with natural…”
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Mechanisms of human cell protection associated with genetic polymorphism by Zasukhina, G. D.

“…Systems ensuring protection of human cells against endogenous and exogenous mutagenic factors are considered in terms of genetic polymorphism. Some protection…”
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Some Aspects of Carcinogenesis Associated with Genetic and Epigenetic Factors by Mikhailov, V. F., Shulenina, L. V., Vasilyeva, I. M., Saleeva, D. V., Zasukhina, G. D.

“…—Various authors have shown that the numerous instances of spontaneous DNA damage (DNA breaks, change in bases) that occur daily in a cell as a result of the…”
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The Effect of Low Doses of Ionizing Radiation on Expression of Genes and Noncoding RNA in Normal and Malignant Human Cells by Mikhailov, V. F., Shulenina, L. V., Raeva, N. F., Vasilieva, I. M., Saleeva, D. V., Neznanova, M. V., Zasukhina, G. D.

“…The effect of X-ray radiation (0.1 Gy) on the expression of a number of genes and regulatory RNA (miRNA and long noncoding RNA) in human lymphocytes and…”
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Cells of patients with Down syndrome—a model to study mechanisms of oncogenesis and hypersensitivity to genotoxicants and antimutagenesis by Zasukhina, G. D., Mikhailov, V. F., Vasilyeva, I. M., Shulenina, L. V.

“…Several molecular and genetic features of cells from Down syndrome patients are considered in comparison to those of healthy donors, as is the possibility of…”
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Polymorphism of detoxification genes and cell resistance to mutagens in patients with Ehlers-Danlos syndrome by Kuz'mina, N S, Shipaeva, E V, Semyachkina, A N, Vasil'eva, I M, Kovalenko, L P, Durnev, A D, Zasukhina, G D

“…Study of polymorphism in 3 genes of the glutathione S-transferase family (GSTM1, GSTT1, and GSTP1) in children with Ehlers-Danlos syndrome whose cells were…”
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Comparative analysis of natural and synthetic antimutagens as regulators of gene expression in human cells under exposure to ionizing radiation by Mikhailov, V F, Shishkina, A A, Vasilyeva, I M, Shulenina, L V, Raeva, N F, Rogozhin, E A, Startsev, M I, Zasukhina, G D, Gromov, S P, Alfimov, M V

“…This paper studies the effect of plant peptides of thionine Ns-W2 extracted from seeds of fennel flower (Nigella sativa) and β-purothionine from wheat germs…”
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Antimutagenic Activity of Wheat Polypeptides in Human Cells Exposed to Cadmium Chloride by Zasukhina, G. D., Vasilyeva, I. M., Kadnikov, I. A., Voronin, M. V., Odintsova, T. I., Korostileva, T. V., Pukhalskii, V. A.

“…Antimutagenic effects of polypeptides isolated from Triticum kiharae wheat plantule extracts have been studied on human cells exposed to cadmium chloride. The…”
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Modulation of gene expression by antimutagens in human cells differing in the sensitivity to mutagens by Zasukhina, G. D., Shagirova, J. M., Babintsev, M. V., Vasilyeva, I. M., Rogozhin, E. A., Odintsova, T. I., Mikhailov, V. F., Gromov, S. P., Vedernikov, A. I., Alfimov, M. V.

“…Evaluation of gene expression allows determination of the level of synthesized product. The parameters of expression of the majority of genes for certain…”
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Comparative analysis of gene expression in human blood cells and in rhabdomyosarcoma cells pretreated with antimutagens by Zasukhina, G. D., Shishkina, A. A., Vasilyeva, I. M., Rogozhin, E. A., Mikhajlov, V. F., Raeva, N. F., Shulenina, L. V., Gromov, S. P., Alfimov, M. V.

“…Determination of gene expression makes it possible to assess the level of synthesized gene product. The transcriptional activity of genes depends on the action…”
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Expression of P53, NPM1, Kras, c-Myc, p14(ARF) genes in blood cells of cancer patients before and after radiation therapy by Shulenina, L V, Ushenkova, L N, Ledin, E V, Shagirova, Zh M, Raeva, N F, Zasukhina, G D, Mikhaĭlov, V F

“…The mRNA levels of P53gene, as well as NPM1, Kras, c-Myc, p14(ARF) genes, which, according to the published data, code for the proteins regulating the p53…”
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Antimutagens (β-purothionin and crown compound) as modulators of expression of genes involved in carcinogenesis in human cells by Zasukhina, G. D., Odintsova, T. I., Shulenina, L. V., Ushenkova, L. N., Mikhailov, V. F., Shagirova, Zh. M., Vedernikov, A. N., Gromov, S. P., Alfimov, M. V.

“…In this study, drugs whose antimutagenic activity was found earlier were tested as gene expression modulators. Antimutagens are compounds that weaken the…”
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Antimutagenic and antioxidant activities of crown compounds in comparison with the effects of garlic extract by Zasukhina, G D, Vasil'eva, I M, Mikhal'chik, E S, Durnev, A D, Gromov, S P, Fedorova, O A, Alfimov, M V

“…Antimutagenic activity of N-carboxyalkyl derivatives of aza- and benzoazacrown compounds was revealed and antimutagenic activity of garlic extract was…”
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