Search Results - "Zastrow, L."

Metallobiology of Lactobacillaceae in the gut microbiome by Huynh, Uyen, Zastrow, Melissa L.

“…Lactobacillaceae are a diverse family of lactic acid bacteria found in the gut microbiota of humans and many animals. These bacteria exhibit beneficial effects…”
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Designing functional metalloproteins: From structural to catalytic metal sites by Zastrow, Melissa L., Pecoraro, Vincent L.

“…► De novo metalloprotein design. ► Structural metal sites: Hg(II) binding to α-helical coiled coils. ► Hydrolytic catalysis by a de novo designed Zn(II)…”
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Hydrolytic catalysis and structural stabilization in a designed metalloprotein by Zastrow, Melissa L., Peacock, Anna F. A., Stuckey, Jeanne A., Pecoraro, Vincent L.

“…Metal ions are an important part of many natural proteins, providing structural, catalytic and electron transfer functions. Reproducing these functions in a…”
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Modulation of extrasynaptic NMDA receptors by synaptic and tonic zinc by Anderson, Charles T., Radford, Robert J., Zastrow, Melissa L., Zhang, Daniel Y., Apfel, Ulf-Peter, Lippard, Stephen J., Tzounopoulos, Thanos

“…Significance As an essential element for living organisms, zinc is a cofactor in many enzymes and regulatory proteins. After the surprising discovery of mobile…”
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A Single-Site Mutation Tunes Fluorescence and Chromophorylation of an Orange Fluorescent Cyanobacteriochrome by Janis, Makena K, Zou, Wenping, Zastrow, Melissa L

“…Cyanobacteriochrome (CBCR) cGMP-specific phosphodiesterase, adenylyl cyclase, and FhlA (GAF) domains bind bilin cofactors to confer sensory wavelengths…”
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Switching from healthy to unhealthy oxidative stress – does the radical type can be used as an indicator? by Lohan, S.B., Ivanov, D., Schüler, N., Berger, B., Zastrow, L., Lademann, J., Meinke, M.C.

“…Ultraviolet (UV) radiation leads to the formation of free radicals, which may cause immunological modulations, skin aging or skin cancer. Sunlight exposure in…”
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Skin type differences in solar‐simulated radiation‐induced oxidative stress by Albrecht, S., Jung, S., Müller, R., Lademann, J., Zuberbier, T., Zastrow, L., Reble, C., Beckers, I., Meinke, M.C.

“…Summary Background Human skin protects the body from external damage, pathogens and oxidative stress factors such as ultraviolet (UV) radiation. Excessive…”
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The missing link--light-induced (280-1,600 nm) free radical formation in human skin by Zastrow, L, Groth, N, Klein, F, Kockott, D, Lademann, J, Renneberg, R, Ferrero, L

“…The recent European recommendation on the efficacy of sunscreen products requests now a minimum ratio of UVA/UVB protection. However, the visible and the…”
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Differential Effects of Transition Metals on Growth and Metal Uptake for Two Distinct Lactobacillus Species by Huynh, Uyen, Qiao, Muxin, King, John, Trinh, Brittany, Valdez, Juventino, Haq, Marium, Zastrow, Melissa L

“…is a genus of Gram-positive bacteria and comprises a major part of the lactic acid bacteria group that converts sugars to lactic acid. species found in the gut…”
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A Far-Red Emitting Probe for Unambiguous Detection of Mobile Zinc in Acidic Vesicles and Deep Tissue by Rivera-Fuentes, Pablo, Wrobel, Alexandra T, Zastrow, Melissa L, Khan, Mustafa, Georgiou, John, Luyben, Thomas T, Roder, John C, Okamoto, Kenichi, Lippard, Stephen J

“…Imaging mobile zinc in acidic environments remains challenging because most small-molecule optical probes display pH-dependent fluorescence. Here we report a…”
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Skin type differences in sun‐induced oxidative stress by Albrecht, S., Jung, S., Müller, R., Lademann, J., Zuberbier, T., Zastrow, L., Reble, C., Beckers, I., Meinke, M.C.

“…Summary Excessive solar (sun) exposure, especially ultraviolet radiation, can lead to sunburn and increased damage to cells, called oxidative stress. This can…”
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Reaction-Based Probes for Imaging Mobile Zinc in Live Cells and Tissues by Zastrow, Melissa L, Radford, Robert J, Chyan, Wen, Anderson, Charles T, Zhang, Daniel Y, Loas, Andrei, Tzounopoulos, Thanos, Lippard, Stephen J

“…Chelatable, or mobile, forms of zinc play critical signaling roles in numerous biological processes. Elucidating the action of mobile Zn­(II) in complex…”
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Routine, Cost-Effective SARS-CoV-2 Surveillance Testing Using Pooled Saliva Limits Viral Spread on a Residential College Campus by Vander Schaaf, Nicole A, Fund, Anthony J, Munnich, Brianna V, Zastrow, Alexi L, Fund, Erin E, Senti, Tanner L, Lynn, Abigail F, Kane, Jonathon J, Love, Jennifer L, Long, Gregory J, Troendle, Nicholas J, Sharda, Daniel R

“…Routine testing for SARS-CoV-2 is rare for institutes of higher education due to prohibitive costs and supply chain delays. During spring 2021, we routinely…”
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Radical production by infrared A irradiation in human tissue by Darvin, M E, Haag, S, Meinke, M, Zastrow, L, Sterry, W, Lademann, J

“…The influence of the ultraviolet (UV) irradiation of the sun on the formation of free radicals in human skin is well investigated. Up to now, only small…”
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Multicenter methodology comparison of the FDA and ISO standard for measurement of in vitro UVA protection of sunscreen products by Bielfeldt, S., Klette, E., Rohr, M., Herzog, B., Grumelard, J., Hanay, C., Heinrich, U., Hansen, P., Kockott, D., Lademann, J., Mendrok-Edinger, C., Peters, S., Rudolph, T., Schläger, T., Tronnier, H., Wiechers, S., Zastrow, L., Pflücker, F.

“…In vitro standard methods are available and accepted worldwide to assess UVA protection of sunscreen products. Though, harmonisation of methods has made…”
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Effect of supplemented and topically applied antioxidant substances on human tissue by Darvin, M, Zastrow, L, Sterry, W, Lademann, J

“…Systemic and topical application of antioxidant substances for the medical treatment and prophylaxis of many diseases as well as additional protection of the…”
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Transition Metals Induce Quenching of Monomeric Near-Infrared Fluorescent Proteins by Zhao, Haowen, Zastrow, Melissa L

“…Transition metals such as zinc and copper are essential in numerous life processes, and both deficiency and toxic overload of these metals are associated with…”
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Designing Hydrolytic Zinc Metalloenzymes by Zastrow, Melissa L, Pecoraro, Vincent L

“…Zinc is an essential element required for the function of more than 300 enzymes spanning all classes. Despite years of dedicated study, questions regarding the…”
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Fluorescent protein-based Zn2+ sensors reveal distinct responses of aerobic and anaerobic Escherichia coli cultures to excess Zn2 by Nguyen, Hazel N., Huynh, Uyen, Zastrow, Melissa L.

“…Zinc ions are required by all known organisms. Maintaining zinc homeostasis by preventing toxic overload while ensuring sufficient acquisition for cellular…”
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Live‐Cell Copper‐Induced Fluorescence Quenching of the Flavin‐Binding Fluorescent Protein CreiLOV by Zou, Wenping, Le, Khoa, Zastrow, Melissa L.

“…CreiLOV is a flavin‐binding fluorescent protein derived from the blue‐light photoreceptor protein family that contains light‐oxygen‐voltage (LOV) sensing…”
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