Search Results - "Zarzour, Maria Alejandra"
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Retrospective evaluation of the role of gemcitabine‐docetaxel in well‐differentiated and dedifferentiated liposarcoma
Published in Cancer medicine (Malden, MA) (01-02-2023)“…Objective Well‐differentiated (WDLPS) and dedifferentiated liposarcoma (DDLPS) account for the majority of liposarcomas. Although gemcitabine‐docetaxel is used…”
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Clinical implications of recurring mutations in myxoid liposarcoma (MLS)
Published in Journal of clinical oncology (01-06-2023)“…11577 Background: MLS is a subset of liposarcoma characterized by a translocation, (t(12;16), FUS-DDIT3 or less frequently t(12;22), EWSR1-DDIT3). Additional…”
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3
Outcomes in late-line systemic treatment in GISTs: Does sequence matter?
Published in Journal of clinical oncology (01-06-2022)“…11542 Background: Ripretinib (R) is approved for 4 th line treatment of GIST based on superior PFS and OS compared to placebo in a phase 3 study, with RR of…”
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Clinical characteristics and outcomes of adult alveolar rhabdomyosarcoma (ARMS) patients on front-line therapies: An MD Anderson Cancer Center (MDACC) case series
Published in Journal of clinical oncology (01-06-2022)“…e23548 Background: Rhabdomyosarcomas are the most common soft tissue sarcoma in children, and the prognosis of pediatric ARMS has improved with the use of…”
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Safety and efficacy of percutaneous image‐guided ablation for soft tissue sarcoma metastases to the liver
Published in Cancer (01-08-2024)“…Purpose To evaluate outcomes following percutaneous image‐guided ablation of soft tissue sarcoma metastases to the liver. Materials and Methods A…”
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Examining Stripes on a Herd of Zebras: Impact of Genomic Matching for Ultrarare Sarcomas in Phase 1 Clinical Trials (SAMBA 102)
Published in Clinical cancer research (17-01-2023)“…Recently, the Connective Tissue Oncology Society published consensus guidelines for recognizing ultrarare sarcomas (URS), defined as sarcomas with an incidence…”
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Real‐world use of palbociclib monotherapy in retroperitoneal liposarcomas at a large volume sarcoma center
Published in International journal of cancer (15-06-2022)“…Palbociclib has been evaluated in early phase trials for well‐differentiated liposarcoma (WDLPS) and dedifferentiated liposarcoma (DDLPS) patients, with…”
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A phase II multi-arm study to test the efficacy of oleclumab and durvalumab in specific sarcoma subtypes
Published in Journal of clinical oncology (01-06-2022)“…TPS11594 Background: Anti-PD 1/PD-L1 blockade alone or in combination with anti-CTLA4 have yielded suboptimal results in most sarcoma subtypes. CD73, an…”
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Modulation of YAP/ TAZ by statins to improve survival in epithelioid hemangioendothelioma (EHE)
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e23527 Background: EHE is a rare soft tissue tumor of endothelial origin. It is distinguished by the pathognomonic WWTR1-CAMTA1 fusion (WWTR1 is…”
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10
Genomics, morphoproteomics, and treatment patterns of alveolar soft part sarcoma patients and response to multiple experimental therapies
Published in Molecular cancer therapeutics (03-03-2020)“…Overexpression of transcription factor 3 in Alveolar soft part sarcoma(ASPS) results in upregulation of cell proliferation pathways. No standard treatment…”
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Does the Primary Tumor Site Drive Biology for Patients With Synovial Sarcoma?
Published in American journal of clinical oncology (03-09-2024)“…We evaluated survival outcomes by primary tumor site in synovial sarcoma (SS) patients with localized and metastatic disease at diagnosis. We conducted a…”
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A phase II multi-arm study of durvalumab and tremelimumab for advanced or metastatic sarcomas
Published in Journal of clinical oncology (20-05-2020)“…Abstract only 11509 Background: The combination of durvalumab (D), (anti- PD-L1) and tremelimumab (T), (anti-CTLA-4), was evaluated to determine activity in…”
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13
Utility of Clinical Next Generation Sequencing Tests in KIT/PDGFRA/SDH Wild-Type Gastrointestinal Stromal Tumors
Published in Cancers (01-05-2024)“…The vast majority of gastrointestinal stromal tumors (GISTs) are driven by activating mutations in , , or components of the succinate dehydrogenase (SDH)…”
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Treatment patterns, efficacy and toxicity of regorafenib in gastrointestinal stromal tumour patients
Published in Scientific reports (25-08-2017)“…Regorafenib was approved as third-line therapy for advanced Gastrointestinal Stromal Tumour (GIST) at a starting dose of 160 mg daily 3 weeks on, 1 week off,…”
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15
Systemic therapy regimen outcomes in metastatic phyllodes tumors of the breast
Published in Journal of clinical oncology (20-05-2018)“…Abstract only…”
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16
Efficacy of front-line chemotherapy for recurrent/metastatic adenosarcoma of the uterus
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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Clinical characteristics of adult alveolar rhabdomyosarcoma (ARMS) patients (Pts) on front-line therapies: An MD Anderson Cancer Center (MDACC) series
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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18
Feasibility and savings of a suspicion of cancer clinic at a large county hospital
Published in Journal of clinical oncology (01-12-2012)“…Abstract only 104 Background: The Lyndon B. Johnson General Hospital (LBJGH) is part of the Harris County Hospital District (HCHD), serving the third largest…”
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19
Whole-exome and targeted sequencing of angiosarcomas: Target identification and treatment implications
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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