Search Results - "Zarytova, V.F."

Toward gene therapy of hypertension: Experimental study on hypertensive ISIAH rats by Repkova, M. N., Levina, A. S., Seryapina, A. A., Shikina, N. V., Bessudnova, E. V., Zarytova, V. F., Markel, A. L.

“…TiO 2 -based nanocomposites were prepared to deliver oligonucleotides into cells. The nanocomposites were designed by the immobilization of…”
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Antisense Oligonucleotides Immobilized on Silicon-Organic Nanoparticles as a Tool for Prolonged Correction of Hypertensive States by Levina, A. S., Repkova, M. N., Klimov, L. O., Ryazanova, M. A., Markel, A. L., Zarytova, V. F.

“…We propose an original method for controlling BP by administration of Si~ODN nanocomposites containing antisense oligonucleotides fixed on silicon-organic…”
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Methods of the Synthesis of Silicon-Containing Nanoparticles Intended for Nucleic Acid Delivery by A. S. Levina, M. N. Repkova, Z. R. Ismagilov, V. F. Zarytova

“…A promising new approach to the treatment of viral infections and genetic diseases associated with damaged or foreign nucleic acids in the body is gene…”
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Synthesis of alkylating oligonucleotide derivatives containing cholesterol or phenazinium residues at their 3′-terminus and their interaction with DNA within mammalian cells by Boutorin, A.S., Gus'kova, L.V., Ivanova, E.M., Kobetz, N.D., Zarytova, V.F., Ryte, A.S., Yurchenko, L.V., Vlassov, V.V.

“…5′-[ 32P]-labelled alkylating decathymidylate [4-( N-2-chloroethyl) N-methylaminobenzyl]-5′-phosphamide derivatives containing cholesterol or phenazinium…”
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The solution structure of a 3′-phenazinium (Pzn) tethered DNA-RNA duplex with a dangling adenosine: r(5′G-AUUGAA3′):d(5TCAATC3′ - Pzn) by Maltseva, T.V., Agback, P., Repkova, M.N., Venyaminova, A.G., Ivanova, E.M., Sandström, A., Zarytova, V.F., Chattopadhyaya, J.

“…The 3'-Pzn group tethered to an oligo-DNA stabilizes a DNA-RNA hybrid duplex structure by 13°C compared to the natural counterpart. This report constitutes the…”
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Porphyrin‐linked oligonucleotides by Frolova, E.I., Ivanova, E.M., Zarytova, V.F., Abramova, T.V., Vlassov, V.V.

“…Oligonucleotide derivatives bearing hemin and deuterohemin groups were synthesized. The derivatives efficiently react with the complementary nucleotide…”
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General scheme of the phosphotriester condensation in the oligodeoxyribonucleotide synthesis with arylsulfonyl chlorides and aryisulfonyl azolides by Zarytova, V.F., Knorre, D.G.

“…Phosphotriester condensation (RO)(R'O)PO2− (PDE) + R"OH (RO)(R'O)(R"O)PO (PTE) in the presence of arylsulfonyl chloride (ArSO2Cl) as well as arylsulfonyl…”
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Photomodification of RNA and DNA fragments by oligonucleotide reagents bearing arylazide groups by Levina, A S, Berezovskii, M V, Venjaminova, A G, Dobrikov, M I, Repkova, M N, Zarytova, V F

“…Photomodification of ribo- and deoxyribo-octanucleotides by oligonucleotide reagents (6- and 7-mers) bearing p-azidotetrafluorobenzamido and…”
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Interaction of cholesterol-conjugated alkylating oligonucleotide derivatives with cellular biopolymers by Ryte, A.S., Karamyshev, V.N., Nechaeva, M.V., Guskova, Z.V., Ivanova, E.M., Zarytova, V.F., Vlassov, V.V.

“…Interactions of oligonucleotide derivatives with mammalian cells and cellular biopolymers have been investigated. The derivatives were oligonucleotides bearing…”
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Sequence-specific chemical modification of a hybrid bacteriophage M 13 single-stranded DNA by alkylating oligonucleotide derivatives by Vlassov, V.V., Zarytova, V.F., Kutyavin, I.V., Mamaev, S.V.

“…Alkylating oligonucleotide derivatives react with the complementary sequences in hybrid M 13mp7 bacteriophage single-stranded DNA and destroy the infecting…”
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Complementary addressed modification of double-stranded DNA within a ternary complex by Fedorova, O.S., Knorre, D.G., Podust, L.M., Zarytova, V.F.

“…Double-stranded DNA containing a d(pG) 18·d(pC) 18 sequence was shown to be selectively alkylated in the vicinity of this fragment using the 5′- p-(…”
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N-(2-Hydroxyethyl)phenazinium derivatives of oligonucleotides as effectors of the sequence-specific modification of nucleic acids with reactive oligonucleotide derivatives by Kutyavin, I.V., Podyminogin, M.A., Bazhina, Yu.N., Fedorova, O.S., Knorre, D.G., Levina, A.S., Mamayev, S.V., Zarytova, V.F.

“…It has been found that mono- and especially diphenazinium derivatives of oligonucleotides complementary to the DNA sequence adjacent to the target sequence of…”
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Porphyrin-linked oligonucleotides: Synthesis and sequence-specific modification of ssDNA by Frolova, E.I., Ivanova, E.M., Zarytova, V.F., Abramova, T.V., Vlassov, V.V.

“…Oligonucleotide derivatives bearing hemin and deuterohemin groups were synthesized. The derivatives efficiently react with the complementary nucleotide…”
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Direct cleavage of a DNA fragment by a bleomycin-oligonucleotide derivative by Sergeyev, D.S., Godovikova, T.S., Zarytova, V.F.

“…Bicomycin A 1 oligonucleotide derivative was used for direct cleavage of a DNA target. In the presence of Fe 2+ ions and 2-mercaptoethanol, Blm-R-pd(CCAAACA)…”
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Affinity chromatography of DNA fragments and P-modified oligonucleotides by Zarytova, V F, Shishkina, I G

“…The wide possibilities for use of affinity chromatography are demonstrated by two examples: (i) isolation of a single-stranded fragment of the tick-borne…”
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5′-Derivatives of oligonucleotides as primers of DNA polymerization catalyzed by AMV reverse transcriptase and Klenow fragment of DNA polymerase 1 by Lokhova, I.A., Nevinsky, G.A., Godovikova, T.S., Ivanova, E.M., Koshkin, A.A., Sergeev, D.S., Frolova, E.I., Rudenko, N.K., Khomov, V.V., Kavsan, V.M., Zarytova, V.F., Lavrik, O.I.

“…The K m and V max values for d(pT) 8 and its derivatives containing various 5′-end groups were estimated in the reaction of polymerization catalyzed with…”
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Reactive oligonucleotide derivatives and sequence-specific modification of nucleic acids by Knorre, D G, Vlassov, V V, Zarytova, V F

“…Selective modification of nucleic acid base sequences can be achieved by complementary oligonucleotides carrying reactive groups. Different types of reactive…”
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31P and 1H NMR investigation of the structure of the phosphorylating intermediates in the phosphodiester approach to the oligonucleotide synthesis by Zarytova, V.F., Graifer, D.M., Ivanova, E.I., Knorre, D.G., Lebedev, A.V., Rezvukhin, A.I.

“…The structure of the reactive phosphorylating derivatives (B) formed by treatment of pdT(Ac) and of the model compound phenylphosphate with condensing reagents…”
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Base-pair exchange kinetics of the imino and amino protons of the 3′-phenazinium tethered DNA-RNA duplex, r( 5′GAUUGAA 3′):d( 5′TCAATC 3′-Pzn), and their comparison with those of B-DNA duplex by Maltseva, T.V., Zarytova, V.F., Chattopadhyaya, J.

“…The dynamics of the opening-closing of the constituent base-pairs as well as of the exchange kinetics of the base-paired imino and amino protons with water in…”
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The mechanism of the chemical synthesis of oligonucleotides and its synthetic consequences by Knorre, D.G., Zarytova, V.F.

“…The data obtained mainly by pulsed MMR spectroscopy on phosphorus nuclei on the mechanism of the internucleotide phosphodiester (PDE)group formation are…”
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