Search Results - "Zarrinpashneh, Elham"

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state by Foretz, Marc, Hébrard, Sophie, Leclerc, Jocelyne, Zarrinpashneh, Elham, Soty, Maud, Mithieux, Gilles, Sakamoto, Kei, Andreelli, Fabrizio, Viollet, Benoit

“…Metformin is widely used to treat hyperglycemia in individuals with type 2 diabetes. Recently the LKB1/AMP-activated protein kinase (LKB1/AMPK) pathway was…”
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mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy by Taneike, Manabu, Nishida, Kazuhiko, Omiya, Shigemiki, Zarrinpashneh, Elham, Misaka, Tomofumi, Kitazume-Taneike, Rika, Austin, Ruth, Takaoka, Minoru, Yamaguchi, Osamu, Gambello, Michael J, Shah, Ajay M, Otsu, Kinya

“…Mammalian target of rapamycin complex 1 (mTORC1) is a key regulator of cell growth, proliferation and metabolism. mTORC1 regulates protein synthesis positively…”
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Ablation of SGK1 impairs endothelial cell migration and tube formation leading to decreased neo-angiogenesis following myocardial infarction by Zarrinpashneh, Elham, Poggioli, Tommaso, Sarathchandra, Padmini, Lexow, Jonas, Monassier, Laurent, Terracciano, Cesare, Lang, Florian, Damilano, Federico, Zhou, Jessica Q, Rosenzweig, Anthony, Rosenthal, Nadia, Santini, Maria Paola

“…Serum and glucocorticoid inducible kinase 1 (SGK1) plays a pivotal role in early angiogenesis during embryonic development. In this study, we sought to define…”
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AMPK: Lessons from transgenic and knockout animals by Viollet, Benoit, Athea, Yoni, Mounier, Remi, Guigas, Bruno, Zarrinpashneh, Elham, Horman, Sandrine, Lantier, Louise, Hebrard, Sophie, Devin-Leclerc, Jocelyne, Beauloye, Christophe, Foretz, Marc, Andreelli, Fabrizio, Ventura-Clapier, Renee, Bertrand, Luc

“…AMP-activated protein kinase (AMPK), a phylogenetically conserved serine/threonine protein kinase, has been proposed to function as a fuel gauge to monitor…”
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Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents by LAI, Yu-Chiang, ZARRINPASHNEH, Elham, JENSEN, Jørgen

“…Insulin and contraction regulate glucose uptake and glycogen synthase (GS) via distinct mechanisms in skeletal muscles, and an additive effect has been…”
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IGF-1Ea induces vessel formation after injury and mediates bone marrow and heart cross-talk through the expression of specific cytokines by Santini, Maria Paola, Lexow, Jonas, Borsellino, Giovanna, Slonimski, Esfir, Zarrinpashneh, Elham, Poggioli, Tommaso, Rosenthal, Nadia

“…► In skeletal muscle overexpression of IGF-1Ea mobilizes bone marrow stem cell favouring tissue repair and integrity. ► We observed that in cardiac muscle…”
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Crucial role for LKB1 to AMPKα2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes by Habets, Daphna D.J., Coumans, Will A., El Hasnaoui, Mohammed, Zarrinpashneh, Elham, Bertrand, Luc, Viollet, Benoit, Kiens, Bente, Jensen, Thomas E., Richter, Erik A., Bonen, Arend, Glatz, Jan F.C., Luiken, Joost J.F.P.

“…Enhanced contractile activity increases cardiac long-chain fatty acid (LCFA) uptake via translocation of CD36 to the sarcolemma, similarly to increase in…”
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AMPKα2 counteracts the development of cardiac hypertrophy induced by isoproterenol by Zarrinpashneh, Elham, Beauloye, Christophe, Ginion, Audrey, Pouleur, Anne-Catherine, Havaux, Xavier, Hue, Louis, Viollet, Benoit, Vanoverschelde, Jean-Louis, Bertrand, Luc

“…As AMP-activated protein kinase (AMPK) controls protein translation, an anti-hypertrophic effect of AMPK has been suggested. However, there is no genetic…”
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Abstract 9386: Attenuation of Post-infarct Cardiac Hypertrophy by Allogeneic Cell-mediated Supplemental Igf-1 Propeptide Delivery by Santini, Maria Paola, Poudel, Bhawana, Poggioli, Tommaso, Bilbao, Daniel, Zarrinpashneh, Elham, Sarathchandra, Padmini, Rosenthal, Nadia

“…Abstract only Background: Cardiovascular remodelling after myocardial infarction leads to cardiac function impairment due to left ventricle dilation,…”
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Differential regulation of eEF2 and p70S6K by AMPKalpha2 in heart by Demeulder, Bénédicte, Zarrinpashneh, Elham, Ginion, Audrey, Viollet, Benoit, Hue, Louis, Rider, Mark H., Vanoverschelde, Jean-Louis, Beauloye, Christophe, Horman, Sandrine, Bertrand, Luc

“…Eukaryotic elongation factor 2 (eEF-2) and mammalian target of rapamycin (mTOR)–p70 ribosomal protein S6 kinase (p70S6K) signaling pathways control protein…”
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The relationship between p38 mitogen-activated protein kinase and AMP-activated protein kinase during myocardial ischemia by Jacquet, Sebastien, Zarrinpashneh, Elham, Chavey, Audrey, Ginion, Audrey, Leclerc, Isabelle, Viollet, Benoit, Rutter, Guy A., Bertrand, Luc, Marber, Michael S.

“…Abstract Objective p38 mitogen-activated protein kinase (p38 MAPK) and AMP-activated protein kinase (AMPK) are activated by, and influence sensitivity to,…”
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Dual cardiac contractile effects of the alpha2-AMPK deletion in low-flow ischemia and reperfusion by Carvajal, Karla, Zarrinpashneh, Elham, Szarszoi, Ondrej, Joubert, Frederic, Athea, Yoni, Mateo, Philippe, Gillet, Brigitte, Vaulont, Sophie, Viollet, Benoit, Bigard, Xavier, Bertrand, Luc, Ventura-Clapier, Renée, Hoerter, Jacqueline A

“…Because the question "is AMP-activated protein kinase (AMPK) alpha(2)-isoform a friend or a foe in the protection of the myocardium against…”
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The relationship between P38–MAPK and AMPK during myocardial ischaemia by Jacquet, Sebastien, Zarrinpashneh, Elham, Chavey, Audrey, Leclerc, Isabelle, Rutter, Guy A, Bertrand, Luc, Marber, Michael S

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Role of the alpha2-isoform of AMP-activated protein kinase in the metabolic response of the heart to no-flow ischemia by Zarrinpashneh, Elham, Carjaval, Karla, Beauloye, Christophe, Ginion, Audrey, Mateo, Philippe, Pouleur, Anne-Catherine, Horman, Sandrine, Vaulont, Sophie, Hoerter, Jacqueline, Viollet, Benoit, Hue, Louis, Vanoverschelde, Jean-Louis, Bertrand, Luc

“…AMP-activated protein kinase (AMPK) is a major sensor and regulator of the energetic state of the cell. Little is known about the specific role of…”
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Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1 by Sakamoto, Kei, Zarrinpashneh, Elham, Budas, Grant R, Pouleur, Anne-Catherine, Dutta, Anindya, Prescott, Alan R, Vanoverschelde, Jean-Louis, Ashworth, Alan, Jovanović, Aleksandar, Alessi, Dario R, Bertrand, Luc

“…Recent studies indicate that the LKB1 is a key regulator of the AMP-activated protein kinase (AMPK), which plays a crucial role in protecting cardiac muscle…”
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AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol by Zarrinpashneh, Elham, Beauloye, Christophe, Ginion, Audrey, Pouleur, Anne-Catherine, Havaux, Xavier, Hue, Louis, Viollet, Benoit, Vanoverschelde, Jean-Louis, Bertrand, Luc

“…As AMP-activated protein kinase (AMPK) controls protein translation, an anti-hypertrophic effect of AMPK has been suggested. However, there is no genetic…”
Get full text

Crucial role for LKB1 to AMPKalpha2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes by Habets, Daphna D J, Coumans, Will A, El Hasnaoui, Mohammed, Zarrinpashneh, Elham, Bertrand, Luc, Viollet, Benoit, Kiens, Bente, Jensen, Thomas E, Richter, Erik A, Bonen, Arend, Glatz, Jan F C, Luiken, Joost J F P

“…Enhanced contractile activity increases cardiac long-chain fatty acid (LCFA) uptake via translocation of CD36 to the sarcolemma, similarly to increase in…”
Get more information