Search Results - "Zarnescu, D C"
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Come FLY with us: toward understanding fragile X syndrome
Published in Genes, brain and behavior (01-08-2005)“…The past few years have seen an increased number of articles using Drosophila as a model system to study fragile X syndrome. Phenotypic analyses have…”
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Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
Published in Nature neuroscience (01-02-2004)“…Fragile X syndrome is caused by a loss of expression of the fragile X mental retardation protein (FMRP). FMRP is a selective RNA-binding protein which forms a…”
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RNA-Mediated Neurodegeneration Caused by the Fragile X Premutation rCGG Repeats in Drosophila
Published in Neuron (Cambridge, Mass.) (28-08-2003)“…Fragile X syndrome carriers have FMR1 alleles, called premutations, with an intermediate number of 5′ untranslated CGG repeats between patients (>200 repeats)…”
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Fragile X Protein Functions with Lgl and the PAR Complex in Flies and Mice
Published in Developmental cell (2005)“…Fragile X syndrome, the most common form of inherited mental retardation, is caused by loss of function for the Fragile X Mental Retardation 1 gene ( FMR1)…”
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Apical Spectrin Is Essential for Epithelial Morphogenesis but Not Apicobasal Polarity in Drosophila
Published in The Journal of cell biology (06-09-1999)“…Changes in cell shape and position drive morphogenesis in epithelia and depend on the polarized nature of its constitutent cells. The spectrin-based membrane…”
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Fragile X protein controls neural stem cell proliferation in the Drosophila brain
Published in Human molecular genetics (01-08-2010)“…Fragile X syndrome (FXS) is the most common form of inherited mental retardation and is caused by the loss of function for Fragile X protein (FMRP), an…”
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Fragile X protein controls the efficacy of mRNA transport in Drosophila neurons
Published in Molecular and cellular neuroscience (01-10-2008)“…Fragile X syndrome, the most common form of inherited mental retardation is caused by mutations in the FMR1 gene. FMR1 encodes an RNA-binding protein thought…”
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Ferrying Wingless across the Synaptic Cleft
Published in Cell (16-10-2009)“…Secreted Wnt morphogens mediate cell-cell communication, but the mechanism of Wnt transfer between cells is unknown. Korkut et al. (2009) report that the…”
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Drosophila betaHeavy-spectrin is essential for development and contributes to specific cell fates in the eye
Published in Development (Cambridge) (01-06-1998)“…The spectrin membrane skeleton is a ubiquitous cytoskeletal structure with several cellular roles, including the maintenance of cell integrity, determination…”
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Drosophila βHeavy-spectrin is essential for development and contributes to specific cell fates in the eye
Published in Development (Cambridge) (01-06-1998)“…The spectrin membrane skeleton is a ubiquitous cytoskeletal structure with several cellular roles, including the maintenance of cell integrity, determination…”
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