Search Results - "Zarina, Shamshad"
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Structural characterization and in vitro lipid binding studies of non-specific lipid transfer protein 1 (nsLTP1) from fennel (Foeniculum vulgare) seeds
Published in Scientific reports (04-12-2020)“…Non-specific lipid transfer proteins (nsLTPs) are cationic proteins involved in intracellular lipid shuttling in growth and reproduction, as well as in defense…”
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Evaluation of anti‐EGFR potential of quinazoline derivatives using molecular docking: An in silico approach
Published in Biotechnology and applied biochemistry (01-06-2022)“…Overexpression of epidermal growth factor receptor (EGFR) is commonly reported in epithelial malignancies such as oral squamous cell carcinoma. Inhibition of…”
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Osmotic stress induced oxidative damage: Possible mechanism of cataract formation in diabetes
Published in Journal of diabetes and its complications (01-07-2012)“…Abstract Chronic hyperglycemia causes increased level of reactive oxygen species which is thought to be involved in the pathogenesis of diabetes associated…”
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Identification of GIMAP7 and Rabl3 as Putative Biomarkers for Oral Squamous Cell Carcinoma Through Comparative Proteomic Approach
Published in Pathology oncology research (01-07-2020)“…Oral squamous cell carcinoma (OSCC) accounts for more than 90% of all oral cancers and has been listed as sixth most common human cancer. Due to late diagnosis…”
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Novel Synergistic Combination of Pamidronate and Temozolomide for Breast Cancer Therapeutics
Published in Current cancer drug targets (01-01-2023)“…Human breast cancer is among one major health concerns with high prevalence and mortality among women worldwide. Various cellular signaling pathways are…”
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Advanced glycation end products in diabetic and non-diabetic human subjects suffering from cataract
Published in AGE (01-09-2011)“…Advanced glycation end products (AGEs) play a pivotal role in loss of lens transparency, i.e., cataract. AGEs formation occurs as a result of sequential…”
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Prenatal diagnosis of maternal serum from mothers carrying β‐thalassemic fetus
Published in Pediatrics international (01-01-2022)“…Background This study focuses on the discovery of protein biomarkers from the maternal serum of β‐thalassemic trait mothers carrying the normal fetus and…”
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Identification of Differentially Expressed Proteins from Smokeless Tobacco Addicted Patients Suffering from Oral Squamous Cell Carcinoma
Published in Pathology oncology research (01-07-2020)“…Oral squamous cell carcinoma (OSCC) is the eight most common malignancy worldwide with an incidence rate of 40% in south-east Asia. Lack of effective…”
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Therapeutic effect of hydrogen peroxide via altered expression of glutathione S-transferase and peroxiredoxin-2 in hepatocellular carcinoma
Published in Hepatobiliary & pancreatic diseases international (01-06-2020)“…Hepatocellular carcinoma (HCC) has a high incidence and mortality that epitomizes one of the prominent causes of cancer-related death globally. Novel…”
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Pharmacoproteomics Profiling of Plasma From β‐Thalassemia Patients in Response to Hydroxyurea Treatment
Published in Journal of clinical pharmacology (01-01-2019)“…β‐Thalassemia is a genetic disorder caused by defects in the β‐globin gene resulting in the absence or reduced synthesis of adult hemoglobin (HbA). Hydroxyurea…”
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Serum HSP90-Alpha and Oral Squamous Cell Carcinoma: A Prospective Biomarker
Published in Protein and peptide letters (01-01-2021)“…This study aims to perform differential protein expression analysis of serum samples from Oral Squamous Cell Carcinoma (OSCC) patients and healthy controls in…”
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SPECTRUM – A MATLAB Toolbox for Proteoform Identification from Top-Down Proteomics Data
Published in Scientific reports (02-08-2019)“…Top-Down Proteomics (TDP) is an emerging proteomics protocol that involves identification, characterization, and quantitation of intact proteins using…”
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The structural characterization and bioactivity assessment of nonspecific lipid transfer protein 1 (nsLTP1) from caraway (Carum carvi) seeds
Published in BMC complementary and alternative medicine (20-07-2023)“…Carum carvi (caraway) of the Apiaceae family has been used in many cultures as a cooking spice and part of the folk medicine. Previous reports primarily focus…”
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Integrated Cheminformatics-Molecular Docking Approach to Drug Discovery Against Viruses
Published in Infectious disorders drug targets (2020)“…In the current study, we present an integrated in silico cheminformaticsmolecular docking approach to screen and test potential therapeutic compounds against…”
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Alendronate and FTI-277 combination as a possible therapeutic approach for hepatocellular carcinoma: An in vitro study
Published in Hepatobiliary & pancreatic diseases international (01-06-2018)“…An important product of mevalonate pathway is downstream synthesis of isoprenoid units that has long been implicated in development and progression of tumor…”
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Differential hemoglobin A sequestration between hemodialysis modalities
Published in Biomolecular concepts (24-05-2017)“…This report evaluates plasma protein patterns, dialysates and protein analysis of used dialysis membranes from the same patient under hemodialysis in three…”
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New anthrarobin acyl derivatives as butyrylcholinesterase inhibitors: synthesis, in vitro and in silico studies
Published in Heliyon (01-07-2017)“…To treat Alzheimer's disease (AD), the available candidates are effective only against mild AD or have side effects. So, a study was planned to synthesis new…”
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The Effect of Alendronate on Proteome of Hepatocellular Carcinoma Cell Lines
Published in International Journal of Proteomics (01-01-2014)“…Cancer is a life threatening disorder effecting 11 million people worldwide annually. Among various types of cancers, Hepatocellular carcinoma (HCC) has a…”
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alpha-Crystallin chaperone function in diabetic rat and human lenses
Published in Molecular and cellular biochemistry (01-01-2002)“…This study focussed on the effect of diabetes on the chaperone function of alpha-crystallin. The authors relied on diabetic rats with a wide range of plasma…”
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Chemical Hypoxic Preconditioning Improves Survival and Proliferation of Mesenchymal Stem Cells
Published in Applied biochemistry and biotechnology (01-07-2024)“…Increasing evidence has demonstrated that mesenchymal stem cells (MSCs) have been linked to tissue regeneration both in vitro and in vivo. However, poor…”
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