Search Results - "Zarin, Payam"

Role of a selecting ligand in shaping the murine γδ-TCR repertoire by Fahl, Shawn P., Coffey, Francis, Kain, Lisa, Zarin, Payam, Dunbrack, Roland L., Teyton, Luc, Zúñiga-Pflücker, Juan Carlos, Kappes, Dietmar J., Wiest, David L.

“…Unlike αβ-T lineage cells, where the role of ligand in intrathymic selection is well established, the role of ligand in the development of γδ-T cells remains…”
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HEB is required for the specification of fetal IL-17-producing γδ T cells by In, Tracy S. H., Trotman-Grant, Ashton, Fahl, Shawn, Chen, Edward L. Y., Zarin, Payam, Moore, Amanda J., Wiest, David L., Zúñiga-Pflücker, Juan Carlos, Anderson, Michele K.

“…IL-17-producing γδ T (γδT17) cells are critical components of the innate immune system. However, the gene networks that control their development are unclear…”
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Interferon-α2b Treatment for COVID-19 Is Associated with Improvements in Lung Abnormalities by Zhou, Qiong, MacArthur, Michael R, He, Xinliang, Wei, Xiaoshan, Zarin, Payam, Hanna, Bola S, Wang, Zi-Hao, Xiang, Xuan, Fish, Eleanor N

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes coronavirus disease 2019 (COVID-19), a lung disease that may progress to systemic…”
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Antibody Class Switching Mediated by Yeast Endonuclease-Generated DNA Breaks by Zarrin, Ali A, Del Vecchio, Catherine, Tseng, Eva, Gleason, Megan, Zarin, Payam, Tian, Ming, Alt, Frederick W

“…Antibody class switching in activated B cells uses class switch recombination (CSR), which joins activation-induced cytidine deaminase (AID)-dependent…”
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Enforcement of γδ-lineage commitment by the pre–T-cell receptor in precursors with weak γδ-TCR signals by Zarin, Payam, Wong, Gladys W., Mohtashami, Mahmood, Wiest, David L., Zúñiga-Pflücker, Juan Carlos

“…Developing thymocytes bifurcate from a bipotent precursor into αβ- or γδ-lineage T cells. Considering this common origin and the fact that the T-cell receptor…”
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Treg cells require Izumo1R to regulate γδT cell-driven inflammation in the skin by Zarin, Payam, Shwartz, Yulia, Ortiz-Lopez, Adriana, Hanna, Bola S, Sassone-Corsi, Martina, Hsu, Ya-Chieh, Mathis, Diane, Benoist, Christophe

“…Izumo1R is a pseudo-folate receptor with an essential role in mediating tight oocyte/spermatozoa contacts during fertilization. Intriguingly, it is also…”
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Stable Expression of FOXP3 and Core Tolerogenic Genes by Engineered Human Tregs by Zarin, Payam, Sassone-Corsi, Martina, Doherty, Abigail, Chicoine, Adam, DeVault, Victoria, Li, Xiang, Yam, Jennifer, Wickham, Thomas, Chen, Tiffany, Depis, Fabien

“…FOXP3 +Regulatory T cells (Tregs) play a critical role in the prevention of fatal autoimmunity and maintaining tissue homeostasis. The functional stability of…”
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Enforcement of gamma delta -lineage commitment by the pre-T-cell receptor in precursors with weak gamma delta -TCR signals by Zarin, Payam, Wong, Gladys W, Mohtashami, Mahmood, Wiest, David L, Zuniga-Pfluecker, Juan Carlos

“…Developing thymocytes bifurcate from a bipotent precursor into alpha beta - or ...-lineage T cells. Considering this common origin and the fact that the T-cell…”
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Integration of T‐cell receptor, Notch and cytokine signals programs mouse γδ T‐cell effector differentiation by Zarin, Payam, In, Tracy SH, Chen, Edward LY, Singh, Jastaranpreet, Wong, Gladys W, Mohtashami, Mahmood, Wiest, David L, Anderson, Michele K, Zúñiga‐Pflücker, Juan Carlos

“…γδ T‐cells perform a wide range of tissue‐ and disease‐specific functions that are dependent on the effector cytokines produced by these cells. However, the…”
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Induction of T Cell Development In Vitro by Delta-Like (Dll)-Expressing Stromal Cells by Mohtashami, Mahmood, Zarin, Payam, Zúñiga-Pflücker, Juan Carlos

“…Recreating the thymic microenvironment in vitro poses a great challenge to immunologists. Until recently, the only approach was to utilize the thymic tissue in…”
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Gamma delta T-cell differentiation and effector function programming, TCR signal strength, when and how much? by Zarin, Payam, Chen, Edward L.Y., In, Tracy S.H., Anderson, Michele K., Zúñiga-Pflücker, Juan Carlos

“…•We review work on the signals affecting the commitment of γδ versus αβ lineage T cells.•We review the interplay between TCR signal strength and E protein…”
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The Role of Environmental Cues in γδ T-Cell Lineage Choice and Functional Programming by Zarin, Payam

“…The thymic landscape provides an array of spatially and temporally controlled cues that guide the development of functionally distinct effector immune cells…”
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Enforcement of [gamma][delta]-lineage commitment by the pre-T-cell receptor in precursors with weak [gamma][delta]-TCR signals by Zarin, Payam, Wong, Gladys W, Mohtashami, Mahmood, Wiest, David L, Zúñiga-Pflücker, Juan Carlos

“…Developing thymocytes bifurcate from a bipotent precursor into αβ- or ...-lineage T cells. Considering this common origin and the fact that the T-cell receptor…”
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GNTI-122: an autologous antigen-specific engineered Treg cell therapy for type 1 diabetes by Uenishi, Gene I, Repic, Marko, Yam, Jennifer Y, Landuyt, Ashley, Saikumar-Lakshmi, Priya, Guo, Tingxi, Zarin, Payam, Sassone-Corsi, Martina, Chicoine, Adam, Kellogg, Hunter, Hunt, Martina, Drow, Travis, Tewari, Ritika, Cook, Peter J, Yang, Soo Jung, Cerosaletti, Karen, Schweinoch, Darius, Guiastrennec, Benjamin, James, Eddie, Patel, Chandra, Chen, Tiffany F, Buckner, Jane H, Rawlings, David J, Wickham, Thomas J, Mueller, Karen T

“…Tregs have the potential to establish long-term immune tolerance in patients recently diagnosed with type 1 diabetes (T1D) by preserving β cell function…”
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