Search Results - "Zareparsi, Sepideh"

Targeting of GFP to Newborn Rods by Nrl Promoter and Temporal Expression Profiling of Flow-Sorted Photoreceptors by Akimoto, Masayuki, Cheng, Hong, Zhu, Dongxiao, Brzezinski, Joseph A., Khanna, Ritu, Filippova, Elena, Oh, Edwin C. T., Jing, Yuezhou, Linares, Jose-Luis, Brooks, Matthew, Zareparsi, Sepideh, Mears, Alan J., Hero, Alfred, Glaser, Tom, Swaroop, Anand

“…The Maf-family transcription factor Nrl is a key regulator of photoreceptor differentiation in mammals. Ablation of the Nrl gene in mice leads to functional…”
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Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration by Hayward, Caroline, Shu, Xinhua, Cideciyan, Artur V., Lennon, Alan, Barran, Perdita, Zareparsi, Sepideh, Sawyer, Lindsay, Hendry, Grace, Dhillon, Baljean, Milam, Ann H., Luthert, Philip J., Swaroop, Anand, Hastie, Nicholas D., Jacobson, Samuel G., Wright, Alan F.

“…A primary feature of age-related macular degeneration (AMD) is the presence of extracellular deposits between the retinal pigment epithelium (RPE) and…”
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Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases by Parapuram, Sunil K, Cojocaru, Radu I, Chang, Jessica R, Khanna, Ritu, Brooks, Matthew, Othman, Mohammad, Zareparsi, Sepideh, Khan, Naheed W, Gotoh, Norimoto, Cogliati, Tiziana, Swaroop, Anand

“…Advanced age contributes to clinical manifestations of many retinopathies and represents a major risk factor for age-related macular degeneration, a leading…”
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Age-Related Macular Degeneration: A High-Resolution Genome Scan for Susceptibility Loci in a Population Enriched for Late-Stage Disease by Abecasis, Gonçalo R., Yashar, Beverly M., Zhao, Yu, Ghiasvand, Noor M., Zareparsi, Sepideh, Branham, Kari E.H., Reddick, Adam C., Trager, Edward H., Yoshida, Shigeo, Bahling, John, Filippova, Elena, Elner, Susan, Johnson, Mark W., Vine, Andrew K., Sieving, Paul A., Jacobson, Samuel G., Richards, Julia E., Swaroop, Anand

“…Age-related macular degeneration (AMD) is a complex multifactorial disease that affects the central region of the retina. AMD is clinically heterogeneous,…”
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CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration by Swaroop, Anand, Abecasis, Gonçalo R, Li, Mingyao, Atmaca-Sonmez, Pelin, Othman, Mohammad, Branham, Kari E H, Khanna, Ritu, Wade, Michael S, Li, Yun, Liang, Liming, Zareparsi, Sepideh

“…In developed countries, age-related macular degeneration is a common cause of blindness in the elderly. A common polymorphism, encoding the sequence variation…”
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Identification of genetic modifiers of age-at-onset for familial Parkinson's disease by Hill-Burns, Erin M, Ross, Owen A, Wissemann, William T, Soto-Ortolaza, Alexandra I, Zareparsi, Sepideh, Siuda, Joanna, Lynch, Timothy, Wszolek, Zbigniew K, Silburn, Peter A, Mellick, George D, Ritz, Beate, Scherzer, Clemens R, Zabetian, Cyrus P, Factor, Stewart A, Breheny, Patrick J, Payami, Haydeh

“…Parkinson's disease (PD) is the most common cause of neurodegenerative movement disorder and the second most common cause of dementia. Genes are thought to…”
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Strong Association of the Y402H Variant in Complement Factor H at 1q32 with Susceptibility to Age-Related Macular Degeneration by Zareparsi, Sepideh, Branham, Kari E.H., Li, Mingyao, Shah, Sapna, Klein, Robert J., Ott, Jurg, Hoh, Josephine, Abecasis, Gonçalo R., Swaroop, Anand

“…Using a large sample of cases and controls from a single center, we show that a T→C substitution in exon 9 (Y402H) of the complement factor H gene is strongly…”
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Extraocular Muscle Morphogenesis and Gene Expression Are Regulated by Pitx2 Gene Dose by Diehl, Adam G, Zareparsi, Sepideh, Qian, Min, Khanna, Ritu, Angeles, Rowena, Gage, Philip J

“…PITX2 gene dose plays a central role in Axenfeld-Rieger syndrome. The purpose of this study was to test the hypothesis that the effects of Pitx2 gene dose on…”
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Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration by Zareparsi, Sepideh, Buraczynska, Monika, Branham, Kari E.H., Shah, Sapna, Eng, Donna, Li, Mingyao, Pawar, Hemant, Yashar, Beverly M., Moroi, Sayoko E., Lichter, Paul R., Petty, Howard R., Richards, Julia E., Abecasis, Gonçalo R., Elner, Victor M., Swaroop, Anand

“…Age-related macular degeneration (AMD) is a genetically heterogeneous disease that leads to progressive and irreversible vision loss among the elderly…”
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Association of Apolipoprotein E Alleles with Susceptibility to Age-Related Macular Degeneration in a Large Cohort from a Single Center by Zareparsi, Sepideh, Reddick, Adam C, Branham, Kari E. H, Moore, Kathryn B, Jessup, Laurie, Thoms, Susan, Smith-Wheelock, Michael, Yashar, Beverly M, Swaroop, Anand

“…To examine the effect of apolipoprotein E (APOE) alleles on age-related macular degeneration (AMD) risk and on age at diagnosis of AMD in a large patient…”
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Primary open angle glaucoma in a Caucasian population is associated with the p53 codon 72 polymorphism by Daugherty, Christopher L, Curtis, Hilda, Realini, Tony, Charlton, Judie F, Zareparsi, Sepideh

“…Apoptosis has been implicated as the mechanism for retinal ganglion cell death in primary open-angle glaucoma (POAG), a complex neurodegenerative disease…”
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Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease : A possible clue to the higher incidence of Alzheimer disease in women by PAYAMI, H, ZAREPARSI, S, SCHELLENBERG, G. D, MONTEE, K. R, SEXTON, G. J, KAYE, J. A, BIRD, T. D, CHANG-EN YU, WIJSMAN, E. M, HESTON, L. L, LITT, M

“…Late-onset Alzheimer disease (AD) is associated with the apolipoprotein E (APOE)-epsilon4 allele. In late-onset familial AD, women have a significantly higher…”
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Evaluation and optimization of procedures for target labeling and hybridization of cDNA microarrays by Yu, Jindan, Othman, Mohammad I, Farjo, Rafal, Zareparsi, Sepideh, MacNee, Sean P, Yoshida, Shigeo, Swaroop, Anand

“…To evaluate and optimize methods of target labeling and microarray hybridization using eye gene microarrays. Standardized protocols that consistently produce…”
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Gene Expression Profile of Native Human Retinal Pigment Epithelium by Buraczynska, Monika, Mears, Alan J, Zareparsi, Sepideh, Farjo, Rafal, Filippova, Elena, Yuan, Yukun, MacNee, Sean P, Hughes, Bret, Swaroop, Anand

“…To generate a profile of genes expressed in the native human retinal pigment epithelium and identify candidate genes for retinal and macular diseases. Two cDNA…”
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Genetic epidemiology of Parkinson's disease by Payami, H, Zareparsi, S

“…The cause of Parkinson's disease (PD) is unknown. The major risk factors identified to date are family history, age, and elements of rural living. Nearly…”
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Seeing the unseen: Microarray-based gene expression profiling in vision by ZAREPARSI, Sepideh, HERO, Alfred, ZACK, Donald J, WILLIAM, Robert W, SWAROOP, Anand

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Predictors of healthy brain aging by Gonzales Mc Neal, M, Zareparsi, S, Camicioli, R, Dame, A, Howieson, D, Quinn, J, Ball, M, Kaye, J, Payami, H

“…To determine if superior health at old age protects against cognitive impairment (CI) and Alzheimer's disease (AD), we prospectively studied 100 optimally…”
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Modulation of the age at onset of Parkinson's disease by apolipoprotein E genotypes by Zareparsi, S, Kaye, J, Camicioli, R, Grimslid, H, Oken, B, Litt, M, Nutt, J, Bird, T, Schellenberg, G, Payami, H

“…Parkinson's disease (PD) patients often develop dementia, and Alzheimer's disease (AD) patients frequently develop parkinsonian signs. The apolipoprotein E…”
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Analysis of the α-synuclein G209A mutation in familial Parkinson's disease by Zareparsi, Sepideh, Kay, Jeffrey, Camicioli, Richard, Kramer, Patricia, Nutt, John, Bird, Thomas, Litt, Michael, Payami, Haydeh

“…Zareparsi et al screened 65 affected members from 40 white Parkinson's disease (PD) kindreds for the G209A mutation. There were no signs of the mutation in any…”
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Familial aggregation of Parkinson disease: a comparative study of early-onset and late-onset disease by Payami, Haydeh, Zareparsi, Sepideh, James, Dora, Nutt, John

“…It is unclear whether late-onset Parkinson disease (PD), which is the most typical and most common form of the disease, has a familial component. Evidence for…”
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