Search Results - "Zaremba, Jeffrey D."

Distinct Contribution of Adult-Born Hippocampal Granule Cells to Context Encoding by Danielson, Nathan B., Kaifosh, Patrick, Zaremba, Jeffrey D., Lovett-Barron, Matthew, Tsai, Joseph, Denny, Christine A., Balough, Elizabeth M., Goldberg, Alexander R., Drew, Liam J., Hen, René, Losonczy, Attila, Kheirbek, Mazen A.

“…Adult-born granule cells (abGCs) have been implicated in cognition and mood; however, it remains unknown how these cells behave in vivo. Here, we have used…”
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Sublayer-Specific Coding Dynamics during Spatial Navigation and Learning in Hippocampal Area CA1 by Danielson, Nathan B., Zaremba, Jeffrey D., Kaifosh, Patrick, Bowler, John, Ladow, Max, Losonczy, Attila

“…The mammalian hippocampus is critical for spatial information processing and episodic memory. Its primary output cells, CA1 pyramidal cells (CA1 PCs), vary in…”
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Dendritic Inhibition in the Hippocampus Supports Fear Learning by Lovett-Barron, Matthew, Kaifosh, Patrick, Kheirbek, Mazen A., Danielson, Nathan, Zaremba, Jeffrey D., Reardon, Thomas R., Turi, Gergely F., Hen, René, Zemelman, Boris V., Losonczy, Attila

“…Fear memories guide adaptive behavior in contexts associated with aversive events. The hippocampus forms a neural representation of the context that predicts…”
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Gating of hippocampal activity, plasticity, and memory by entorhinal cortex long-range inhibition by Basu, Jayeeta, Zaremba, Jeffrey D., Cheung, Stephanie K., Hitti, Frederick L., Zemelman, Boris V., Losonczy, Attila, Siegelbaum, Steven A.

“…The cortico-hippocampal circuit is critical for storage of associational memories. Most studies have focused on the role in memory storage of the excitatory…”
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SIMA: Python software for analysis of dynamic fluorescence imaging data by Kaifosh, Patrick, Zaremba, Jeffrey D, Danielson, Nathan B, Losonczy, Attila

“…Fluorescence imaging is a powerful method for monitoring dynamic signals in the nervous system. However, analysis of dynamic fluorescence imaging data remains…”
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NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism by Tu, Shichun, Akhtar, Mohd Waseem, Escorihuela, Rosa Maria, Amador-Arjona, Alejandro, Swarup, Vivek, Parker, James, Zaremba, Jeffrey D., Holland, Timothy, Bansal, Neha, Holohan, Daniel R., Lopez, Kevin, Ryan, Scott D., Chan, Shing Fai, Yan, Li, Zhang, Xiaofei, Huang, Xiayu, Sultan, Abdullah, McKercher, Scott R., Ambasudhan, Rajesh, Xu, Huaxi, Wang, Yuqiang, Geschwind, Daniel H., Roberts, Amanda J., Terskikh, Alexey V., Rissman, Robert A., Masliah, Eliezer, Lipton, Stuart A., Nakanishi, Nobuki

“…Transcription factor MEF2C regulates multiple genes linked to autism spectrum disorder (ASD), and human MEF2C haploinsufficiency results in ASD, intellectual…”
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Cortical reactivations of recent sensory experiences predict bidirectional network changes during learning by Sugden, Arthur U., Zaremba, Jeffrey D., Sugden, Lauren A., McGuire, Kelly L., Lutas, Andrew, Ramesh, Rohan N., Alturkistani, Osama, Lensjø, Kristian K., Burgess, Christian R., Andermann, Mark L.

“…Salient experiences are often relived in the mind. Human neuroimaging studies suggest that such experiences drive activity patterns in visual association…”
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Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells by Zhu, Saiyong, Ambasudhan, Rajesh, Sun, Woong, Kim, Hyun Jung, Talantova, Maria, Wang, Xiaojing, Zhang, Mingliang, Zhang, Yu, Laurent, Timothy, Parker, James, Kim, Han-Seop, Zaremba, Jeffrey D, Saleem, Sofiyan, Sanz-Blasco, Sara, Masliah, Eliezer, McKercher, Scott R, Cho, Yee Sook, Lipton, Stuart A, Kim, Janghwan, Ding, Sheng

“…Dear Editor, We previously developed a novel paradigm of cell activation and signaling-directed （CASD） lineage conversion for direct reprogramming of…”
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Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo by Li, Hao, Radford, Jonathan C, Ragusa, Michael J, Shea, Katherine L, McKercher, Scott R, Zaremba, Jeffrey D, Soussou, Walid, Nie, Zhiguo, Kang, Yeon-Joo, Nakanishi, Nobuki, Okamoto, Shu-ichi, Roberts, Amanda J, Schwarz, John J, Lipton, Stuart A

“…Emerging evidence suggests that myocyte enhancer factor 2 (MEF2) transcription factors act as effectors of neurogenesis in the brain, with MEF2C the…”
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S-Nitrosylation-Mediated Redox Transcriptional Switch Modulates Neurogenesis and Neuronal Cell Death by Okamoto, Shu-ichi, Nakamura, Tomohiro, Cieplak, Piotr, Chan, Shing Fai, Kalashnikova, Evgenia, Liao, Lujian, Saleem, Sofiyan, Han, Xuemei, Clemente, Arjay, Nutter, Anthony, Sances, Sam, Brechtel, Christopher, Haus, Daniel, Haun, Florian, Sanz-Blasco, Sara, Huang, Xiayu, Li, Hao, Zaremba, Jeffrey D., Cui, Jiankun, Gu, Zezong, Nikzad, Rana, Harrop, Anne, McKercher, Scott R., Godzik, Adam, Yates, John R., Lipton, Stuart A.

“…Redox-mediated posttranslational modifications represent a molecular switch that controls major mechanisms of cell function. Nitric oxide (NO) can mediate…”
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MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian rat model by Cho, Eun-Gyung, Zaremba, Jeffrey D, McKercher, Scott R, Talantova, Maria, Tu, Shichun, Masliah, Eliezer, Chan, Shing Fai, Nakanishi, Nobuki, Terskikh, Alexey, Lipton, Stuart A

“…Human embryonic stem cells (hESCs) can potentially differentiate into any cell type, including dopaminergic neurons to treat Parkinson's disease (PD), but…”
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Impaired hippocampal place cell dynamics in a mouse model of the 22q11.2 deletion by Zaremba, Jeffrey D, Diamantopoulou, Anastasia, Danielson, Nathan B, Grosmark, Andres D, Kaifosh, Patrick W, Bowler, John C, Liao, Zhenrui, Sparks, Fraser T, Gogos, Joseph A, Losonczy, Attila

“…Using two-photon Ca 2+ imaging in hippocampal area CA1 of Df(16)A +/− mice, an animal model of 22q11.2 deletion syndrome, the authors found a reduction in…”
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Autistic Phenotype from MEF2C Knockout Cells by Lipton, Stuart A., Li, Hao, Zaremba, Jeffrey D., McKercher, Scott R., Cui, Jiankun, Kang, Yeon-Joo, Nie, Zhiguo, Soussou, Walid, Talantova, Maria, Okamoto, Shu-Ichi, Nakanishi, Nobuki

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Spatial Memory in Health and Disease: Hippocampal Stability Deficits in the Df(16)A+/– Mouse Model of Schizophrenia by Zaremba, Jeffrey D

“…Recognizing and understanding where and when events occurred is essential for normal learning and memory of life experiences. Disruptions in the normal…”
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