Search Results - "Zarakas, Marissa A"

Inhibition of Bruton tyrosine kinase in patients with severe COVID-19 by Roschewski, Mark, Lionakis, Michail S, Sharman, Jeff P, Roswarski, Joseph, Goy, Andre, Monticelli, M Andrew, Roshon, Michael, Wrzesinski, Stephen H, Desai, Jigar V, Zarakas, Marissa A, Collen, Jacob, Rose, Keith, Hamdy, Ahmed, Izumi, Raquel, Wright, George W, Chung, Kevin K, Baselga, Jose, Staudt, Louis M, Wilson, Wyndham H

“…Patients with severe COVID-19 have a hyperinflammatory immune response suggestive of macrophage activation. Bruton tyrosine kinase (BTK) regulates macrophage…”
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C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection by Desai, Jigar V., Kumar, Dhaneshwar, Freiwald, Tilo, Chauss, Daniel, Johnson, Melissa D., Abers, Michael S., Steinbrink, Julie M., Perfect, John R., Alexander, Barbara, Matzaraki, Vasiliki, Snarr, Brendan D., Zarakas, Marissa A., Oikonomou, Vasileios, Silva, Lakmali M., Shivarathri, Raju, Beltran, Emily, Demontel, Luciana Negro, Wang, Luopin, Lim, Jean K., Launder, Dylan, Conti, Heather R., Swamydas, Muthulekha, McClain, Micah T., Moutsopoulos, Niki M., Kazemian, Majid, Netea, Mihai G., Kumar, Vinod, Köhl, Jörg, Kemper, Claudia, Afzali, Behdad, Lionakis, Michail S.

“…Systemic candidiasis is a common, high-mortality, nosocomial fungal infection. Unexpectedly, it has emerged as a complication of anti-complement C5-targeted…”
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BTK drives neutrophil activation for sterilizing antifungal immunity by Desai, Jigar V, Zarakas, Marissa A, Wishart, Andrew L, Roschewski, Mark, Aufiero, Mariano A, Donkó, Ágnes, Wigerblad, Gustaf, Shlezinger, Neta, Plate, Markus, James, Matthew R, Lim, Jean K, Uzel, Gulbu, Bergerson, Jenna Re, Fuss, Ivan, Cramer, Robert A, Franco, Luis M, Clark, Emily S, Khan, Wasif N, Yamanaka, Daisuke, Chamilos, Georgios, El-Benna, Jamel, Kaplan, Mariana J, Staudt, Louis M, Leto, Thomas L, Holland, Steven M, Wilson, Wyndham H, Hohl, Tobias M, Lionakis, Michail S

“…We describe a previously-unappreciated role for Bruton's tyrosine kinase (BTK) in fungal immune surveillance against aspergillosis, an unforeseen complication…”
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Fungal Infections with Ibrutinib and Other Small-Molecule Kinase Inhibitors by Zarakas, Marissa A., Desai, Jigar V., Chamilos, Georgios, Lionakis, Michail S.

“…Purpose of Review Small-molecule kinase inhibitors (SMKIs) have revolutionized the management of malignant and autoimmune disorders. Emerging clinical reports…”
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NADPH oxidase correction by mRNA transfection of apheresis granulocytes in chronic granulomatous disease by De Ravin, Suk See, Brault, Julie, Meis, Ronald J., Li, Linhong, Theobald, Narda, Bonifacino, Aylin C., Lei, Hong, Liu, Taylor Q., Koontz, Sherry, Corsino, Cristina, Zarakas, Marissa A., Desai, Jigar V., Clark, Aaron B., Choi, Uimook, Metzger, Mark E., West, Kamille, Highfill, Steven L., Kang, Elizabeth, Kuhns, Douglas B., Lionakis, Michail S., Stroncek, David F., Dunbar, Cynthia E., Tisdale, John F., Donahue, Robert E., Dahl, Gary A., Malech, Harry L.

“…Granulocytes from patients with chronic granulomatous disease (CGD) have dysfunctional phagocyte reduced nicotinamide adenine dinucleotide phosphate (NADPH)…”
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BTK drives neutrophil activation for sterilizing antifungal immunity by Desai, Jigar V, Zarakas, Marissa A, Wishart, Andrew L, Roschewski, Mark, Aufiero, Mariano A, Donko, Agnes, Wigerblad, Gustaf, Shlezinger, Neta, Plate, Markus, James, Matthew R, Lim, Jean K, Uzel, Gulbu, Bergerson, Jenna R E, Fuss, Ivan, Cramer, Robert A, Franco, Luis M, Clark, Emily S, Khan, Wasif N, Yamanaka, Daisuke, Chamilos, Georgios, El-Benna, Jamel, Kaplan, Mariana J, Staudt, Louis M, Leto, Thomas L, Holland, Steven M, Wilson, Wyndham H, Hohl, Tobias M, Lionakis, Michail S

“…We describe a previously unappreciated role for Bruton's tyrosine kinase (BTK) in fungal immune surveillance against aspergillosis, an unforeseen complication…”
Get full text