Search Results - "Zappa, Maria F"
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A new adenovector system for implementing thymulin gene therapy for inflammatory disorders
Published in Molecular immunology (01-07-2017)“…Thymulin is a thymic peptide possessing anti-inflammatory effects. In order to manipulate thymulin expression in gene therapy studies, we built a bidirectional…”
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Mesenchymal Stem Cells Therapy Improved the Streptozotocin-Induced Behavioral and Hippocampal Impairment in Rats
Published in Molecular neurobiology (01-02-2020)“…Sporadic Alzheimer’s disease (sAD) is the most prevalent neurodegenerative pathology with no effective therapy until date. This disease promotes hippocampal…”
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Intracerebroventricular Delivery of Human Umbilical Cord Mesenchymal Stem Cells as a Promising Therapy for Repairing the Spinal Cord Injury Induced by Kainic Acid
Published in Stem cell reviews and reports (01-02-2020)“…Spinal cord injury (SCI) is a common pathological condition that leads to permanent or temporal loss of motor and autonomic functions. Kainic acid (KA), an…”
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Intracerebroventricular streptozotocin induces impaired Barnes maze spatial memory and reduces astrocyte branching in the CA1 and CA3 hippocampal regions
Published in Journal of Neural Transmission (01-12-2018)“…Sporadic Alzheimer’s disease (SAD) is the most common form of dementia; therefore, there is an urgent need for a model that recapitulates the main pathologic…”
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Mesenchymal stem cell therapy improves spatial memory and hippocampal structure in aging rats
Published in Behavioural brain research (18-11-2019)“…•Mesenchymal stem cells (MSCs) are of interest for the treatment of brain pathologies.•Spatial memory in aged female rats significantly improved after MSC…”
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Adenovirus-Mediated Transduction of Insulin-Like Growth Factor 1 Protects Hippocampal Neurons from the Toxicity of Aβ Oligomers and Prevents Memory Loss in an Alzheimer Mouse Model
Published in Molecular neurobiology (01-03-2020)“…Alzheimer’s disease (AD) is the main cause of dementia in the elderly. Although activation of brain insulin signaling has been shown to be neuroprotective, to…”
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Umbilical Cord Cell Therapy Improves Spatial Memory in Aging Rats
Published in Stem cell reviews (01-08-2019)“…There is a growing interest in the potential of adult stem cells for implementing regenerative medicine in the brain. We assessed the effect of…”
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The thymulin-lactotropic axis in rodents: thymectomy, immunoneutralization and gene transfer studies
Published in Neuroimmunomodulation (01-01-2013)“…There is clear evidence on the existence of a thymus-pituitary axis which seems to be particularly important during perinatal life. In particular, the thymic…”
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