Search Results - "Zapico, M."

Mutant K-Ras increases GSK-3β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer by Zhang, J-S, Koenig, A, Harrison, A, Ugolkov, A V, Fernandez-Zapico, M E, Couch, F J, Billadeau, D D

“…Glycogen synthase kinase-3 beta (GSK-3β) is overexpressed in a number of human malignancies and has been shown to contribute to tumor cell proliferation and…”
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A hypothermia mimetic molecule (zr17-2) reduces ganglion cell death and electroretinogram distortion in a rat model of intraorbital optic nerve crush (IONC) by Contartese, Daniela S, Rey-Funes, Manuel, Peláez, Rafael, Soliño, Manuel, Fernández, Juan C, Nakamura, Ronan, Ciranna, Nicolás S, Sarotto, Aníbal, Dorfman, Verónica B, López-Costa, Juan J, Zapico, José M, Ramos, Ana, de Pascual-Teresa, Beatriz, Larrayoz, Ignacio M, Loidl, César F, Martínez, Alfredo

“…Ocular and periocular traumatisms may result in loss of vision. Our previous work showed that therapeutic hypothermia prevents retinal damage caused by…”
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A hypothermia mimetic molecule (zr17-2) reduces ganglion cell death, gliosis, and electroretinogram distortion in male rats subjected to perinatal asphyxia by Rey-Funes, Manuel, Fernández, Juan Carlos, Peláez, Rafael, Soliño, Manuel, Contartese, Daniela S., Ciranna, Nicolás S., Nakamura, Ronan, Sarotto, Aníbal, Dorfman, Verónica B., Zapico, José M., Ramos, Ana, de Pascual-Teresa, Beatriz, López-Costa, Juan José, Larrayoz, Ignacio M., Martínez, Alfredo, Loidl, César Fabián

“…Introduction: Perinatal asphyxia (PA) represents a major problem in perinatology and may cause visual losses, including blindness. We, and others, have shown…”
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Chlamydia trachomatis genotypes A and B from urogenital specimens of patients in Spain: molecular characterization by Piñeiro, L., Isaksson, J., Zapico, M., Cilla, G., Herrmann, B.

“…Chlamydia trachomatis ompA genotypes A and B, primarily associated with trachoma, were unexpectedly detected in urogenital samples of patients in Spain, a…”
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The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation by Loncle, C, Molejon, M I, Lac, S, Tellechea, J I, Lomberk, G, Gramatica, L, Fernandez Zapico, M F, Dusetti, N, Urrutia, R, Iovanna, J L

“…Both clinical and experimental evidence have firmly established that chronic pancreatitis, in particular in the context of Kras oncogenic mutations,…”
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MMP-2 selectivity in hydroxamate-type inhibitors by Serra, P, Bruczko, M, Zapico, J M, Puckowska, A, Garcia, M A, Martin-Santamaria, S, Ramos, A, de Pascual-Teresa, B

“…Extracellular matrix metalloproteinases (MMPs) are a family of zinc-dependent neutral endopeptidases involved in physiological and pathological processes,…”
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Role of RPTPβ/ζ in neuroinflammation and microglia-neuron communication by Fernández-Calle, Rosalía, Galán-Llario, Milagros, Gramage, Esther, Zapatería, Begoña, Vicente-Rodríguez, Marta, Zapico, José M., de Pascual-Teresa, Beatriz, Ramos, Ana, Ramos-Álvarez, M. Pilar, Uribarri, María, Ferrer-Alcón, Marcel, Herradón, Gonzalo

“…Pleiotrophin (PTN) is a cytokine that is upregulated in different neuroinflammatory disorders. Using mice with transgenic PTN overexpression in the brain ( Ptn…”
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GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis by Kurita, S, Mott, J L, Almada, L L, Bronk, S F, Werneburg, N W, Sun, S-Y, Roberts, L R, Fernandez-Zapico, M E, Gores, G J

“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis through its cognate receptors death receptor 4 (DR4) and death receptor 5…”
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Inhibition of Receptor Protein Tyrosine Phosphatase β/ζ Reduces Alcohol Intake in Rats by Calleja‐Conde, Javier, Fernández‐Calle, Rosalía, Zapico, José M., Ramos, Ana, Pascual‐Teresa, Beatriz, Bühler, Kora‐Mareen, Echeverry‐Alzate, Victor, Giné, Elena, Rodríguez de Fonseca, Fernando, López‐Moreno, Jose Antonio, Herradón, Gonzalo

“…Background Pleiotrophin (PTN) and midkine (MK) are cytokines that are up‐regulated in the prefrontal cortex (PFC) after alcohol administration and have been…”
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Implication of the PTN/RPTPβ/ζ Signaling Pathway in Acute Ethanol Neuroinflammation in Both Sexes: A Comparative Study with LPS by Rodríguez-Zapata, María, Galán-Llario, Milagros, Cañeque-Rufo, Héctor, Sevillano, Julio, Sánchez-Alonso, María Gracia, Zapico, José M, Ferrer-Alcón, Marcel, Uribarri, María, Pascual-Teresa, Beatriz de, Ramos-Álvarez, María Del Pilar, Herradón, Gonzalo, Pérez-García, Carmen, Gramage, Esther

“…Binge drinking during adolescence increases the risk of alcohol use disorder, possibly by involving alterations of neuroimmune responses. Pleiotrophin (PTN) is…”
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The Relationship of Anti‐MICA Antibodies and MICA Expression with Heart Allograft Rejection by Suárez‐Álvarez, B., López‐Vázquez, A., Gonzalez, M. Zapico, Fdez‐Morera, J. L., Díaz‐Molina, B., Blanco‐Gelaz, M. A., Pascual, D., Martínez‐Borra, J., Muro, M., Álvarez‐López, M. R., López‐Larrea, C.

“…The role of MICA antibodies in acute heart allograft rejection was examined utilizing 190 pre‐ and post‐transplant serum samples from 44 patients collected…”
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Aurora A phosphorylation of the epigenetic regulator HP1γ mediates cell division in pancreatic cancer cells by Grzenda, A, Leonard, P, Urrutia, G, Mathison, A, Fernandez-Zapico, M, Urrutia, R, Lomberk, G

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Modeling of metabolic gene networks regulated by KLF-mediated epigenetic pathways working at the intersection of pancreatic cancer and diabetes by Lomberk, G, Grzenda, A, Mathison, A, Calvo, E, Fernandez Zapico, M, Iovanna, J, Urrutia, R

“…[...]this study demonstrate that, in addition to the known role of KLF11 in the regulation of cell cycle, this protein may impact pancreatic cancer growth…”
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Zirconium-Mediated Coupling Reactions of Amines and Enol or Allyl Ethers: Synthesis of Allyl- and Homoallylamines by Barluenga, José, Rodríguez, Félix, Álvarez-Rodrigo, Lucía, Zapico, José M., Fañanás, Francisco J.

“…An easy and efficient zirconium‐mediated synthesis of allylamines from simple amines and enol ethers is described. This strategy also allows the synthesis of…”
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Whooping cough in the first year of life in a region with high vaccination coverage by Aristimuño, H, Muga, O, Cilla, G, Piñeiro, L, Zapico, M S, Pérez-Yarza, E G

“…Despite vaccination, reports of cases and outbreaks of pertussis (whooping cough) continue to appear sporadically, sometimes in young children who are at…”
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An mSin3A interaction domain links the transcriptional activity of KLF11 with its role in growth regulation by Urrutia, Raul, Fernandez-Zapico, Martin E, Mladek, Ann, Ellenrieder, Volker, Folch-Puy, Emma, Miller, Laurence

“…KLF11 is a biochemical paradigm for a subset of proteins that repress transcription via a Mad1‐like mSin3A interacting domain (SID). The biological role of…”
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Outcome of pregnancy in a hypothyroid woman with resistance to thyroid hormone treated with triiodothyronine by Boix, E, Picó, A, Zapico, M, López, A, Mauri, M

“…Epidemiological and research data have shown the significant role of maternal thyroid hormone in fetal neurologic development. It has been suggested that…”
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38 by Truty, M.J, Tsuji, S, Lomberk, G.A, Fernandez-Zapico, M, Urrutia, R

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The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes KrasG12D-mediated pancreatic cancer initiation by Loncle, C, Molejon, M I, Lac, S, Tellechea, J I, Lomberk, G, Gramatica, L, Fernandez Zapico, M F, Dusetti, N, Urrutia, R, Iovanna, J L

“…Both clinical and experimental evidence have firmly established that chronic pancreatitis, in particular in the context of Kras oncogenic mutations,…”
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Reduction of Cisplatin-Induced Nephrotoxicity in Vivo by Selenomethionine: The Effect on Cisplatin–DNA Adducts by García Sar, Daniel, Montes-Bayón, Maria, Blanco González, Elisa, Sierra Zapico, Luisa M, Sanz-Medel, Alfredo

“…Cisplatin is one of the most effective chemotherapeutic agents, although its clinical use is limited by severe renal toxicity. This toxicity seems to be…”
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