Search Results - "Zapadka, Thomas E."

Aryl Hydrocarbon Receptor Agonist VAF347 Impedes Retinal Pathogenesis in Diabetic Mice by Zapadka, Thomas E, Lindstrom, Sarah I, Batoki, Julia C, Lee, Chieh A, Taylor, Brooklyn E, Howell, Scott J, Taylor, Patricia R

“…Diabetic retinopathy is the leading cause of blindness in the working-age population worldwide. Although the cause of diabetic retinopathy is multifactorial,…”
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IL-17A Enhances Retinal Neovascularization by Taylor, Brooklyn E, Lee, Chieh A, Zapadka, Thomas E, Zhou, Amy Y, Barber, Katherine G, Taylor, Zakary R R, Howell, Scott J, Taylor, Patricia R

“…Retinal neovascularization occurs in proliferative diabetic retinopathy, neovascular glaucoma, and age-related macular degeneration. This type of retinal…”
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RORγt Inhibitor-SR1001 Halts Retinal Inflammation, Capillary Degeneration, and the Progression of Diabetic Retinopathy by Zapadka, Thomas E, Lindstrom, Sarah I, Taylor, Brooklyn E, Lee, Chieh A, Tang, Jie, Taylor, Zakary R R, Howell, Scott J, Taylor, Patricia R

“…Diabetic retinopathy is a diabetes-mediated retinal microvascular disease that is the leading cause of blindness in the working-age population worldwide…”
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Retinal Inflammation, Oxidative Stress, and Vascular Impairment Is Ablated in Diabetic Mice Receiving XMD8-92 Treatment by Howell, Scott J, Lee, Chieh A, Batoki, Julia C, Zapadka, Thomas E, Lindstrom, Sarah I, Taylor, Brooklyn E, Taylor, Patricia R

“…The global number of diabetics continues to rise annually. As diabetes progresses, almost all of Type I and more than half of Type II diabetics develop…”
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Inhibition of CD40-TRAF6-dependent inflammatory activity halts the onset of diabetic retinopathy in streptozotocin-diabetic mice by Howell, Scott J., Lee, Chieh A., Zapadka, Thomas E., Lindstrom, Sarah I., Taylor, Brooklyn E., Taylor, Zakary R. R., Barber, Katherine G., Taylor, Patricia R.

“…Diabetes initiates inflammation that can impair the retinal vasculature, and lead to diabetic retinopathy; one of the leading causes of blindness. Inflammatory…”
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Diabetes-mediated IL-17A enhances retinal inflammation, oxidative stress, and vascular permeability by Sigurdardottir, Sigrun, Zapadka, Thomas E., Lindstrom, Sarah I., Liu, Haitao, Taylor, Brooklyn E., Lee, Chieh A., Kern, Timothy S., Taylor, Patricia R.

“…•Th17 cells and IL-17-producing neutrophils adhere to diabetic retinal vasculature.•Muller glia, photoreceptors, and retinal endothelial cells constitutively…”
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Diabetes induces IL-17A-Act1-FADD-dependent retinal endothelial cell death and capillary degeneration by Lindstrom, Sarah I., Sigurdardottir, Sigrun, Zapadka, Thomas E., Tang, Jie, Liu, Haitao, Taylor, Brooklyn E., Smith, Dawn G., Lee, Chieh A., DeAngelis, John, Kern, Timothy S., Taylor, Patricia R.

“…Diabetes leads to progressive complications such as diabetic retinopathy, which is the leading cause of blindness within the working-age population worldwide…”
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Specific retinal neurons regulate context-dependent defensive responses to visual threat by Lee, Tracy, Weinberg-Wolf, Hannah, Zapadka, Thomas E, Rudenko, Andrii, Demb, Jonathan B, Kim, In-Jung

“…While encountering a visual threat, an animal assesses multiple factors to choose an appropriate defensive strategy. For example, when a rodent detects a…”
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