Search Results - "Zantema, A"

Cyclin D1 is an essential mediator of apoptotic neuronal cell death by Kranenburg, O., Eb, A. J., Zantema, A.

“…Many neurons in the developing nervous system undergo programmed cell death, or apoptosis. However, the molecular mechanism underlying this phenomenon is…”
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Genome-wide assessment of differential roles for p300 and CBP in transcription regulation by Ramos, Y. F. M., Hestand, M. S., Verlaan, M., Krabbendam, E., Ariyurek, Y., van Galen, M., van Dam, H., van Ommen, G.-J. B., den Dunnen, J. T., Zantema, A., 't Hoen, P. A. C.

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Heterodimer formation of cJun and ATF‐2 is responsible for induction of c‐jun by the 243 amino acid adenovirus E1A protein by Dam, H., Duyndam, M., Rottier, R., Bosch, A., Vries‐Smits, L., Herrlich, P., Zantema, A., Angel, P., Eb, A.J.

“…The adenovirus E1A proteins differentially regulate AP‐1‐responsive genes. Collagenase and stromelysin are repressed by E1A, whereas the expression of c‐jun is…”
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Inhibition of Cyclin-Dependent Kinase Activity Triggers Neuronal Differentiation of Mouse Neuroblastoma Cells by Kranenburg, Onno, Scharnhorst, Volkher, Van der Eb, Alex J., Zantema, Alt

“…Studies on the molecular mechanisms underlying neuronal differentiation are frequently performed using cell lines established from neuroblastomas. In this…”
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Characterization of cloned chicken anemia virus DNA that contains all elements for the infectious replication cycle by Noteborn, M H, de Boer, G F, van Roozelaar, D J, Karreman, C, Kranenburg, O, Vos, J G, Jeurissen, S H, Hoeben, R C, Zantema, A, Koch, G

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A‐ and B‐type cyclins differentially modulate substrate specificity of cyclin‐cdk complexes by Peeper, D.S., Parker, L.L., Ewen, M.E., Toebes, M., Hall, F.L., Xu, M., Zantema, A., Eb, A.J., Piwnica‐Worms, H.

“…Both cyclins A and B associate with and thereby activate cyclin‐dependent protein kinases (cdks). We have investigated which component in the cyclin‐cdk…”
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Adenovirus E1A negatively and positively modulates transcription of AP‐1 dependent genes by dimer‐specific regulation of the DNA binding and transactivation activities of Jun by Hagmeyer, B.M., König, H., Herr, I., Offringa, R., Zantema, A., Eb, A., Herrlich, P., Angel, P.

“…Adenovirus E1A proteins inhibit expression of the collagenase gene but activate expression of the c‐jun gene. Both effects are mediated by TPA‐responsive…”
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Heat shock protein 27 and alpha B-crystallin can form a complex, which dissociates by heat shock by ZANTEMA, A, VERLAAN-DE VRIES, MAASDAM, D, BOL, S, VAN DER EB, A

“…We have previously demonstrated that in non-oncogenic adenovirus-transformed baby rat kidney cells a complex of hsp27 and a 22-kDa protein is present, which is…”
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Cyclin-dependent kinases and pRb: regulators of the proliferation-differentiation switch by Kranenburg, O., van der Eb, A.J., Zantema, A.

“…The retinoblastoma susceptibility gene ( RB1) is essential for normal embryonic development. Loss of RB1 leads to uncontrolled proliferation of a number of…”
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Downregulation of MHC class I expression due to interference with p105‐NF kappa B1 processing by Ad12E1A by Schouten, G.J., Eb, A.J., Zantema, A.

“…We have previously demonstrated that expression of major histocompatibility complex (MHC) class I genes is repressed in baby rat kidney cells transformed by…”
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Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells by Zantema, A, Schrier, P I, Davis-Olivier, A, van Laar, T, Vaessen, R T, van der EB, A J

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Modulation of gene expression by adenovirus transformation by Zantema, A, van der Eb, A J

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The N-terminal region of the adenovirus type 5 E1A proteins can repress expression of cellular genes via two distinct but overlapping domains by Dorsman, J C, Hagmeyer, B M, Veenstra, J, Elfferich, P, Nabben, N, Zantema, A, van der Eb, A J

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Adenovirus-E1A proteins transform cells by sequestering regulatory proteins by PEEPER, D. S, ZANTEMA, A

“…Cell transformation by adenovirus-E1A proteins is mediated by binding to cellular proteins whose functions are thereby inactivated or altered. The various…”
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The expression of heat shock protein hsp27 and a complexed 22-kilodalton protein is inversely correlated with oncogenicity of adenovirus-transformed cells by ZANTEMA, A, DE JONG, E, LARDENOIJE, R, VAN DER EB, A. J

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The CR1 and CR3 domains of the adenovirus type 5 E1A proteins can independently mediate activation of ATF-2 by Duyndam, M C, van Dam, H, van der Eb, A J, Zantema, A

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Association between the cellular p53 and the adenovirus 5 E1B‐55kd proteins reduces the oncogenicity of Ad‐transformed cells by Heuvel, S. J., Laar, T., Kast, W. M., Melief, C. J., Zantema, A., Eb, A. J.

“…The association of the cellular p53 protein with the E1B‐55kd protein of adenovirus 5 (Ad5) is thought to result in inactivation of the p53 recessive oncogene…”
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Repression of cyclin D1 expression does not contribute to initiation or maintenance of cell transformation by adenovirus type 5 E1 by Kranenburg, O, Keblusek, P, Van der Eb, A J, Zantema, A

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p53 shares an antigenic determinant with proteins of 92 and 150 kilodaltons that may be involved in senescence of human cells by VAN DEN HEUVEL, S. J. L, THE, S. I, KLEIN, B, JOCHEMSEN, A. G, ZANTEMA, A, VAN DER EB, A. J

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Induction of polyploidy in Adenovirus E1-transformed cells by the mitotic inhibitor colcemid by Kranenburg, O., Van der Eb, A.J., Zantema, A.

“…Adenovirus-transformed cells were tested for their ability to synthesize DNA in the presence of cell cycle inhibitory drugs. We show that transformed cells are…”
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