Search Results - "Zanninelli, G."
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LPI-labile plasma iron in iron overload
Published in Best practice & research. Clinical haematology (01-06-2005)“…Labile plasma iron (LPI) represents a component of non-transferrin-bound iron (NTBI) that is both redox-active and chelatable, capable of permeating into…”
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Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid-induced colorectal fibrosis
Published in European journal of clinical investigation (01-02-2009)“…Background Transforming growth factor‐β (TGF‐β)/Smad3 signalling plays a central role in tissue fibrogenesis, acting as a potent stimulus of extracellular…”
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Prevention of colonic fibrosis by Boswellia and Scutellaria extracts in rats with colitis induced by 2,4,5-trinitrobenzene sulphonic acid
Published in European journal of clinical investigation (01-06-2008)“…ABSTRACT Background Currently, no effective preventive measures or medical therapies are available for intestinal fibrosis and, thus, surgery remains the only…”
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Chelation and mobilization of cellular iron by different classes of chelators
Published in Molecular pharmacology (01-05-1997)“…Iron chelators belonging to three distinct chemical families were assessed in terms of their physicochemical properties and the kinetics of iron chelation in…”
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Smad3-null mice lack interstitial cells of Cajal in the colonic wall
Published in European journal of clinical investigation (01-01-2006)“…Background Transforming growth factor‐β (TGF‐β)/Smad's signalling pathway plays a pivotal role in organogenesis, oncogenesis, inflammation, repair and…”
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PA.142 PREVENTION OF TNBS-INDUCED COLONIC FIBROSIS IN RATS BY BOSWELLIA AND SCUTELLARIA EXTRACTS
Published in Digestive and liver disease (2008)Get full text
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Biliary excretion of plasma non-transferrin-bound iron in rats: pathogenetic importance in iron-overload disorders
Published in The American journal of physiology (01-07-1994)“…Plasma non-transferrin-bound iron (NTB-iron) is a potentially toxic form of iron, which is efficiently taken up by the normal, as well as the chronically…”
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Prevention and treatment of intestinal fibrosis: up-regulate smad7 or inhibit smad3 expression?
Published in European journal of clinical investigation (01-11-2008)Get full text
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The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes
Published in Molecular and cellular biology (01-09-1999)“…In this study, activation of the mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) signalling pathway was analyzed in…”
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Iron overload and the biliary route
Published in Advances in experimental medicine and biology (1994)Get more information
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Effect of the terpenic compound epomediol on biliary secretion and bile composition in the rat
Published in Journal of hepatology (01-01-1992)“…The aim of the present investigation was to define the role of the synthetic terpenoid epomediol on biliary secretion in rats recovered from anaesthesia, in…”
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Lymphocyte function tests in cirrhotic patients under treatment with spironolactone and potassium canrenoate
Published in Journal of international medical research (01-11-1988)“…This controlled study in cirrhotic patients investigated whether two antialdosteronic steroids, spironolactone (100-200 mg/day; n = 12 patient pairs) and…”
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Intracellular and extracellular labile iron pools
Published in Advances in experimental medicine and biology (2002)Get more information
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Research update for articles published in EJCI in 2008
Published in European journal of clinical investigation (01-09-2010)“…Eur J Clin Invest 2010; 40 (9): 770–789…”
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Targeted disruption of TGF-beta/sMAD3 signaling confers resistance to intestinal fibrosis
Published in Digestive and liver disease (01-04-2006)Get full text
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SMAD3-null mice lack interstitial cells of cajal (ICC) in the colonic wall
Published in Digestive and liver disease (01-04-2006)Get full text
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Anemia in -thalassemia patients targets hepatic hepcidin transcript levels independently of iron metabolism genes controlling hepcidin expression
Published in Haematologica (Roma) (01-01-2008)“…1 Inserm U-522, IFR 140, University Hospital Pontchaillou, Rennes, France 2 Ospedale San Eugenio, Day Hospital Talassemie, Rome, Italy 3 Ospedale Oncologico,…”
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The labile iron pool of hepatocytes in chronic and acute iron overload and chelator-induced iron deprivation
Published in Journal of hepatology (2002)“…Background : The cytosolic labile iron pool (LIP) is a transitory, catalytically active compartment that has been implicated in cell iron homeostasis and in…”
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P168 PREVENTION OF TNBS-INDUCED COLONIC FIBROSIS IN RATS BY BOSWELLIA AND SCUTELLARIA EXTRACTS
Published in Journal of Crohn's and colitis supplements (01-02-2008)Get full text
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17 OP Experimental colitis in rats is exacerbated by chronic stress the role of substance P
Published in Digestive and liver disease (01-06-2002)Get full text
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