Search Results - "Zanna, Paola"
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Trop‐2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis
Published in Neoplasia (New York, N.Y.) (01-04-2021)“…Trop-2 is a transmembrane signal transducer that can induce cancer growth. Using antibody targeting and N-terminal Edman degradation, we show here that Trop-2…”
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Translational control mechanisms in cutaneous malignant melanoma: the role of eIF2α
Published in Journal of translational medicine (11-01-2019)“…Melanoma cells develop adaptive responses in order to cope with particular conditions of tumor microenvironment, characterized by stress conditions and…”
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3
Melanogenesis in visceral tissues of Salmo salar. A link between immunity and pigment production?
Published in Biochemistry and cell biology (01-12-2012)“…Melanogenesis is mostly studied in melanocytes and melanoma cells, but much less is known about other pigment cell systems. Liver, spleen, kidney, and other…”
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Mechanism of dimerization of the human melanocortin 1 receptor
Published in Biochemical and biophysical research communications (04-04-2008)“…The melanocortin 1 receptor (MC1R) is a dimeric G protein-coupled receptor expressed in melanocytes, where it regulates the amount and type of melanins…”
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Molecular cloning and biochemical characterization of the skin tyrosinase from Rana esculenta L
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01-03-2009)“…Amphibian tyrosinases display unique and poorly understood properties such as seasonal activity variations, different activities in dorsal and ventral skin and…”
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New insight into the role of metabolic reprogramming in melanoma cells harboring BRAF mutations
Published in Biochimica et biophysica acta (01-11-2016)“…This study explores the V600BRAF-MITF-PGC-1α axis and compares metabolic and functional changes occurring in primary and metastatic V600BRAF melanoma cell…”
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Translational control mechanisms in cutaneous malignant melanoma: the role of eIF2[alpha]
Published in Journal of translational medicine (11-01-2019)“…Background Melanoma cells develop adaptive responses in order to cope with particular conditions of tumor microenvironment, characterized by stress conditions…”
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Novel s-HPV49 Transgenic Mouse Model of Upper Digestive Tract Cancer
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…These findings suggest the utility of little studied HPV strains in understanding tissue-specific mechanisms of carcinogenesis, which involve environmental…”
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Novel ß-HPV49 Transgenic Mouse Model of Upper Digestive Tract Cancer
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…The beta genus of human papillomaviruses (ß-HPV) includes approximately 50 different viral types that are subdivided into five species (ß-1 through ß-5)…”
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10
Melanocortin 1 receptor mutations impact differentially on signalling to the cAMP and the ERK mitogen-activated protein kinase pathways
Published in FEBS letters (06-10-2009)“…Melanocortin 1 receptor (MC1R), a Gs protein-coupled receptor expressed in melanocytes, is a major determinant of skin pigmentation, phototype and cancer risk…”
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Trop‐1 are conserved growth stimulatory molecules that mark early stages of tumor progression
Published in Cancer (15-07-2007)“…BACKGROUND. Trop‐1 is a cell‐cell adhesion regulatory molecule that is overexpressed by a large fraction of tumors in man. METHODS. To identify fundamental,…”
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The mitochondrial master regulator gene PGC1alpha in novel sporadic melanoma cell lines: correlations with BRAF mutational status
Published in Journal of translational medicine (06-05-2014)“…Doc number: P9…”
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Role of G Protein-Coupled Receptor Kinases in the Homologous Desensitization of the Human and Mouse Melanocortin 1 Receptors
Published in Molecular endocrinology (Baltimore, Md.) (01-04-2005)“…The melanocortin 1 receptor, a G protein-coupled receptor positively coupled to adenylyl cyclase, is a key regulator of epidermal melanocyte proliferation and…”
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Molecular and Ultrastructural Analysis of a Multiphasic Oral Malignant Melanoma
Published in Ultrastructural pathology (01-02-2011)“…Melanomas of the oral cavity are extremely rare. Their rarity and their independence on exposure to UV radiation make them particularly interesting. The…”
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Original Research Article: Melanogenic Response of the Kupffer Cells of Rana Esculenta L. to Melanocyte Stimulating Hormone
Published in Pigment cell research (01-04-2004)“…We have previously shown that Kupffer cells (KCs) of Rana esculenta L. possess melanogenic ability. The melanogenic enzyme activities in these cells are…”
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Melanogenic Response of the Kupffer Cells of Rana Esculenta L. to Melanocyte Stimulating Hormone
Published in Pigment cell research (01-04-2004)“…We have previously shown that Kupffer cells (KCs) of Rana esculenta L. possess melanogenic ability. The melanogenic enzyme activities in these cells are…”
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