Search Results - "Zanini, Graziela"
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Geospatial distribution of intestinal parasitic infections in Rio de Janeiro (Brazil) and its association with social determinants
Published in PLoS neglected tropical diseases (01-03-2017)“…Intestinal parasitic infections remain among the most common infectious diseases worldwide. This study aimed to estimate their prevalence and provide a…”
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2
Nitric oxide synthase dysfunction contributes to impaired cerebroarteriolar reactivity in experimental cerebral malaria
Published in PLoS pathogens (01-06-2013)“…Cerebrovascular dysfunction plays a key role in the pathogenesis of cerebral malaria. In experimental cerebral malaria (ECM) induced by Plasmodium berghei…”
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3
Molecular Characterization of Giardia lamblia: First Report of Assemblage B in Human Isolates from Rio de Janeiro (Brazil)
Published in PloS one (12-08-2016)“…Despite the high prevalence of giardiasis, the genetic characterization of Giardia lamblia has been poorly documented in Brazil and molecular epidemiology…”
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4
Efficacy of different nitric oxide-based strategies in preventing experimental cerebral malaria by Plasmodium berghei ANKA
Published in PloS one (13-02-2012)“…Low nitric oxide (NO) bioavailability plays a role in the pathogenesis of human as well as of experimental cerebral malaria (ECM) caused by Plasmodium berghei…”
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5
Nitric Oxide Protection Against Murine Cerebral Malaria Is Associated With Improved Cerebral Microcirculatory Physiology
Published in The Journal of infectious diseases (15-05-2011)“…Cerebral malaria (CM) is a leading cause of death in Plasmodium falciparum infections. In the Plasmodium berghei ANKA (PbA) murine model, CM pathogenesis is…”
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6
Exogenous nitric oxide decreases brain vascular inflammation, leakage and venular resistance during Plasmodium berghei ANKA infection in mice
Published in Journal of neuroinflammation (07-06-2011)“…Cerebral malaria (CM) is a lethal complication of Plasmodium falciparum infections. In the Plasmodium berghei ANKA (PbA) murine model, CM is associated with…”
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Murine Cerebral Malaria Is Associated with a Vasospasm-Like Microcirculatory Dysfunction, and Survival upon Rescue Treatment Is Markedly Increased by Nimodipine
Published in The American journal of pathology (01-03-2010)“…Brain hemodynamics in cerebral malaria (CM) is poorly understood, with apparently conflicting data showing microcirculatory hypoperfusion and normal or even…”
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NO-Donor Dihydroartemisinin Derivatives as Multitarget Agents for the Treatment of Cerebral Malaria
Published in Journal of medicinal chemistry (08-10-2015)“…Hybrid products in which the dihydroartemisinin scaffold is combined with NO-donor furoxan and NONOate moieties have been synthesized and studied as potential…”
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9
Transdermal Glyceryl Trinitrate as an Effective Adjunctive Treatment with Artemether for Late-Stage Experimental Cerebral Malaria
Published in Antimicrobial Agents and Chemotherapy (01-11-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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10
Slow and continuous delivery of a low dose of nimodipine improves survival and electrocardiogram parameters in rescue therapy of mice with experimental cerebral malaria
Published in Malaria journal (24-04-2013)“…Human cerebral malaria (HCM) is a life-threatening complication caused by Plasmodium falciparum infection that continues to be a major global health problem…”
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11
CD4+ T cells apoptosis in Plasmodium vivax infection is mediated by activation of both intrinsic and extrinsic pathways
Published in Malaria journal (05-01-2015)“…Reduction in the number of circulating blood lymphocytes (lymphocytopaenia) has been reported during clinical episodes of malaria and is normalized after…”
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12
S-nitrosoglutathione Prevents Experimental Cerebral Malaria
Published in Journal of neuroimmune pharmacology (01-06-2012)“…Administration of the exogenous nitric oxide (NO) donor dipropylenetriamine-NONOate (DPTA-NO) to mice during Plasmodium berghei ANKA (PbA) infection largely…”
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13
Phenotypic profiling of CD8(+) T cells during Plasmodium vivax blood-stage infection
Published in BMC infectious diseases (31-01-2015)“…For a long time, the role of CD8(+) T cells in blood-stage malaria was not considered important because erythrocytes do not express major histocompatibility…”
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14
Cerebral tissue oxygenation impairment during experimental cerebral malaria
Published in Virulence (15-11-2013)“…Ischemia and hypoxia have been implicated in cerebral malaria (CM) pathogenesis, although direct measurements of hypoxia have not been conducted. C57BL/6 mice…”
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15
Enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without HIV co-infection in a reference hospital in Rio de Janeiro (2000-2006)
Published in The Brazilian journal of infectious diseases (01-12-2009)“…Tuberculosis and intestinal parasites affect primarily low social and economic level populations, living clustered in precarious habitational settings. One of…”
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16
Dengue infection as a potential trigger of an imported Plasmodium ovale malaria relapse or a long incubation period in a non-endemic malaria region
Published in International journal of infectious diseases (01-03-2016)“…Highlights • This is the first case report of concurrent dengue and Plasmodium ovale infections. • Dengue fever (DF) seems to be able to trigger an ovale…”
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Immunization of Saimiri sciureus monkeys with a recombinant hybrid protein derived from the Plasmodium falciparum antigen glutamate-rich protein and merozoite surface protein 3 can induce partial protection with Freund and Montanide ISA720 adjuvants
Published in Clinical and diagnostic laboratory immunology (01-02-2005)“…The immunogenicity and efficacy of a hybrid recombinant protein derived from the N-terminal end of the glutamate-rich protein (GLURP) and the C-terminal…”
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18
Similar Cytokine Responses and Degrees of Anemia in Patients with Plasmodium falciparum and Plasmodium vivax Infections in the Brazilian Amazon Region
Published in Clinical and Vaccine Immunology (01-04-2008)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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19
Monoclonal auto-antibodies and sera of autoimmune patients react with Plasmodium falciparum and inhibit its in vitro growth
Published in Memórias do Instituto Oswaldo Cruz (01-08-2011)“…The relationship between autoimmunity and malaria is not well understood. To determine whether autoimmune responses have a protective role during malaria, we…”
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Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation
Published in The Lancet global health (01-10-2017)“…Malaria was eliminated from southern and southeastern Brazil over 50 years ago. However, an increasing number of autochthonous episodes attributed to…”
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