Search Results - "Zanini, Graziela"

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    Geospatial distribution of intestinal parasitic infections in Rio de Janeiro (Brazil) and its association with social determinants by Faria, Clarissa Perez, Zanini, Graziela Maria, Dias, Gisele Silva, da Silva, Sidnei, de Freitas, Marcelo Bessa, Almendra, Ricardo, Santana, Paula, Sousa, Maria do Céu

    Published in PLoS neglected tropical diseases (01-03-2017)
    “…Intestinal parasitic infections remain among the most common infectious diseases worldwide. This study aimed to estimate their prevalence and provide a…”
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    Journal Article
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    Nitric oxide synthase dysfunction contributes to impaired cerebroarteriolar reactivity in experimental cerebral malaria by Ong, Peng Kai, Melchior, Benoît, Martins, Yuri C, Hofer, Anthony, Orjuela-Sánchez, Pamela, Cabrales, Pedro, Zanini, Graziela M, Frangos, John A, Carvalho, Leonardo J M

    Published in PLoS pathogens (01-06-2013)
    “…Cerebrovascular dysfunction plays a key role in the pathogenesis of cerebral malaria. In experimental cerebral malaria (ECM) induced by Plasmodium berghei…”
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    Molecular Characterization of Giardia lamblia: First Report of Assemblage B in Human Isolates from Rio de Janeiro (Brazil) by Faria, Clarissa Perez, Zanini, Graziela Maria, Dias, Gisele Silva, da Silva, Sidnei, Sousa, Maria do Céu

    Published in PloS one (12-08-2016)
    “…Despite the high prevalence of giardiasis, the genetic characterization of Giardia lamblia has been poorly documented in Brazil and molecular epidemiology…”
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    Efficacy of different nitric oxide-based strategies in preventing experimental cerebral malaria by Plasmodium berghei ANKA by Martins, Yuri C, Zanini, Graziela M, Frangos, John A, Carvalho, Leonardo J M

    Published in PloS one (13-02-2012)
    “…Low nitric oxide (NO) bioavailability plays a role in the pathogenesis of human as well as of experimental cerebral malaria (ECM) caused by Plasmodium berghei…”
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    Nitric Oxide Protection Against Murine Cerebral Malaria Is Associated With Improved Cerebral Microcirculatory Physiology by Cabrales, Pedro, Zanini, Graziela M., Meays, Diana, Frangos, John A., Carvalho, Leonardo J. M.

    Published in The Journal of infectious diseases (15-05-2011)
    “…Cerebral malaria (CM) is a leading cause of death in Plasmodium falciparum infections. In the Plasmodium berghei ANKA (PbA) murine model, CM pathogenesis is…”
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    Exogenous nitric oxide decreases brain vascular inflammation, leakage and venular resistance during Plasmodium berghei ANKA infection in mice by Zanini, Graziela M, Cabrales, Pedro, Barkho, Wisam, Frangos, John A, Carvalho, Leonardo J M

    Published in Journal of neuroinflammation (07-06-2011)
    “…Cerebral malaria (CM) is a lethal complication of Plasmodium falciparum infections. In the Plasmodium berghei ANKA (PbA) murine model, CM is associated with…”
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    Murine Cerebral Malaria Is Associated with a Vasospasm-Like Microcirculatory Dysfunction, and Survival upon Rescue Treatment Is Markedly Increased by Nimodipine by Cabrales, Pedro, Zanini, Graziela M, Meays, Diana, Frangos, John A, Carvalho, Leonardo J.M

    Published in The American journal of pathology (01-03-2010)
    “…Brain hemodynamics in cerebral malaria (CM) is poorly understood, with apparently conflicting data showing microcirculatory hypoperfusion and normal or even…”
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    NO-Donor Dihydroartemisinin Derivatives as Multitarget Agents for the Treatment of Cerebral Malaria by Bertinaria, Massimo, Orjuela-Sanchez, Pamela, Marini, Elisabetta, Guglielmo, Stefano, Hofer, Anthony, Martins, Yuri C., Zanini, Graziela M., Frangos, John A., Gasco, Alberto, Fruttero, Roberta, Carvalho, Leonardo J. M.

    Published in Journal of medicinal chemistry (08-10-2015)
    “…Hybrid products in which the dihydroartemisinin scaffold is combined with NO-donor furoxan and NONOate moieties have been synthesized and studied as potential…”
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    Transdermal Glyceryl Trinitrate as an Effective Adjunctive Treatment with Artemether for Late-Stage Experimental Cerebral Malaria by Orjuela-Sánchez, Pamela, Ong, Peng Kai, Zanini, Graziela M, Melchior, Benoît, Martins, Yuri C, Meays, Diana, Frangos, John A, Carvalho, Leonardo J M

    Published in Antimicrobial Agents and Chemotherapy (01-11-2013)
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    Slow and continuous delivery of a low dose of nimodipine improves survival and electrocardiogram parameters in rescue therapy of mice with experimental cerebral malaria by Martins, Yuri C, Clemmer, Leah, Orjuela-Sánchez, Pamela, Zanini, Graziela M, Ong, Peng Kai, Frangos, John A, Carvalho, Leonardo J M

    Published in Malaria journal (24-04-2013)
    “…Human cerebral malaria (HCM) is a life-threatening complication caused by Plasmodium falciparum infection that continues to be a major global health problem…”
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    S-nitrosoglutathione Prevents Experimental Cerebral Malaria by Zanini, Graziela M., Martins, Yuri C., Cabrales, Pedro, Frangos, John A., Carvalho, Leonardo J. M.

    Published in Journal of neuroimmune pharmacology (01-06-2012)
    “…Administration of the exogenous nitric oxide (NO) donor dipropylenetriamine-NONOate (DPTA-NO) to mice during Plasmodium berghei ANKA (PbA) infection largely…”
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    Cerebral tissue oxygenation impairment during experimental cerebral malaria by Cabrales, Pedro, Martins, Yuri C, Ong, Peng Kai, Zanini, Graziela M, Frangos, John A, Carvalho, Leonardo JM

    Published in Virulence (15-11-2013)
    “…Ischemia and hypoxia have been implicated in cerebral malaria (CM) pathogenesis, although direct measurements of hypoxia have not been conducted. C57BL/6 mice…”
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    Monoclonal auto-antibodies and sera of autoimmune patients react with Plasmodium falciparum and inhibit its in vitro growth by Brahimi, Karima, Martins, Yuri Chaves, Zanini, Graziela Maria, Ferreira-da-Cruz, Maria de Fátima, Daniel-Ribeiro, Cláudio Tadeu

    Published in Memórias do Instituto Oswaldo Cruz (01-08-2011)
    “…The relationship between autoimmunity and malaria is not well understood. To determine whether autoimmune responses have a protective role during malaria, we…”
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