Male cytogenetic evaluation prior to assisted reproduction procedures performed in Mar del Plata, Argentina

Male cytogenetic evaluation prior to assisted reproduction procedures performed in Mar del Plata, Argentina

This paper aimed to estimate the frequency of occurrence and the types of chromosomal abnormalities found in 141 infertile men with abnormal semen parameters. the frequency and type of chromosomal abnormalities were determined with male mitotic karyotype analysis from peripheral blood through chromo...

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Bibliographic Details
Published in:JBRA assisted reproduction Vol. 20; no. 2; pp. 62 - 65
Main Authors: Poli, María N, Miranda, Lucía A López, Gil, Eduardo Daniel, Zanier, Germán Justo, Iriarte, Pedro Fernández, Zanier, Justo H Mario, Coco, Roberto
Format: Journal Article
Language:English
Published: Brazil 01-05-2016
Subjects:
Argentina
Azoospermia - epidemiology
Azoospermia - genetics
Chromosome Aberrations - statistics & numerical data
Cohort Studies
Genetic Counseling
Humans
Incidence
Karyotype
Karyotyping
Male
Oligospermia - epidemiology
Oligospermia - genetics
Reproductive Techniques, Assisted
chromosomal anomalies
male infertility
assisted reproduction technology
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Summary:This paper aimed to estimate the frequency of occurrence and the types of chromosomal abnormalities found in 141 infertile men with abnormal semen parameters. the frequency and type of chromosomal abnormalities were determined with male mitotic karyotype analysis from peripheral blood through chromosome banding techniques before assisted reproduction procedures. In this series of 141 infertile men, 19 (13%) had chromosomal anomalies and 35 (25%) had polymorphic variants. The main chromosome abnormalities were reciprocal translocations and marker chromosomes in mosaic. These results stress the relevance of cytogenetic studies for infertile males as a diagnostic tool and a valuable input in genetic counseling.
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ISSN:1518-0557
1518-0557
DOI:10.5935/1518-0557.20160015