Search Results - "Zanier, Elisa R"
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1
The ischemic environment drives microglia and macrophage function
Published in Frontiers in neurology (08-04-2015)“…Cells of myeloid origin, such as microglia and macrophages, act at the crossroads of several inflammatory mechanisms during pathophysiology. Besides…”
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2
Accuracy of intracranial pressure monitoring: systematic review and meta-analysis
Published in Critical care (London, England) (02-12-2015)“…Intracranial pressure (ICP) measurement is used to tailor interventions and to assist in formulating the prognosis for traumatic brain injury patients…”
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3
Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer’s mice
Published in Cell death and differentiation (01-01-2021)“…The multiplicity of systems affected in Alzheimer’s disease (AD) brains calls for multi-target therapies. Although mesenchymal stem cells (MSC) are promising…”
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4
Induction of a transmissible tau pathology by traumatic brain injury
Published in Brain (London, England : 1878) (01-09-2018)“…See Sastre et al. (doi:10.1093/brain/awy225) for a scientific commentary on this article. Traumatic brain injury (TBI) is a risk factor for subsequent…”
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5
Neuro-Inflammation Modulation and Post-Traumatic Brain Injury Lesions: From Bench to Bed-Side
Published in International journal of molecular sciences (23-09-2022)“…Head trauma is the most common cause of disability in young adults. Known as a silent epidemic, it can cause a mosaic of symptoms, whether neurological…”
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6
Markers of blood-brain barrier disruption increase early and persistently in COVID-19 patients with neurological manifestations
Published in Frontiers in immunology (15-12-2022)“…Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is associated with disorders affecting the peripheral and the central nervous system. A high…”
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ECoG spiking activity and signal dimension are early predictive measures of epileptogenesis in a translational mouse model of traumatic brain injury
Published in Neurobiology of disease (01-09-2023)“…The latency between traumatic brain injury (TBI) and the onset of epilepsy (PTE) represents an opportunity for counteracting epileptogenesis…”
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8
Macrophages are essential for maintaining a M2 protective response early after ischemic brain injury
Published in Neurobiology of disease (01-12-2016)“…Abstract Resident microglia and recruited macrophages are major contributors to the post-ischemic inflammatory response. Initially considered functionally…”
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9
Hypertonic sodium lactate infusion reduces vasopressor requirements and biomarkers of brain and cardiac injury after experimental cardiac arrest
Published in Critical care (London, England) (22-04-2023)“…Prognosis after resuscitation from cardiac arrest (CA) remains poor, with high morbidity and mortality as a result of extensive cardiac and brain injury and…”
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10
Bone Marrow Mesenchymal Stromal Cells Drive Protective M2 Microglia Polarization After Brain Trauma
Published in Neurotherapeutics (01-07-2014)“…Microglia/macrophages (M) are major contributors to postinjury inflammation, but they may also promote brain repair in response to specific environmental…”
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11
Versatility of the complement system in neuroinflammation, neurodegeneration and brain homeostasis
Published in Frontiers in cellular neuroscience (07-11-2014)“…The immune response after brain injury is highly complex and involves both local and systemic events at the cellular and molecular level. It is associated to a…”
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12
Suspected intracranial hypertension in COVID-19 patients with severe respiratory failure
Published in PloS one (19-09-2024)“…COVID-19 patients may exhibit neurological symptoms due to direct viral damage, systemic inflammatory syndrome, or treatment side effects. Mechanical…”
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13
Aβ1-6A2V(D) peptide, effective on Aβ aggregation, inhibits tau misfolding and protects the brain after traumatic brain injury
Published in Molecular psychiatry (01-06-2023)“…Alzheimer’s disease (AD), the leading cause of dementia in older adults, is a double proteinopathy characterized by amyloid-β (Aβ) and tau pathology. Despite…”
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14
Virtual Reality for Traumatic Brain Injury
Published in Frontiers in neurology (16-05-2018)“…In this perspective, we discuss the potential of virtual reality (VR) in the assessment and rehabilitation of traumatic brain injury, a silent epidemic of…”
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15
Cognitive Assessment in SARS-CoV-2 Patients: A Systematic Review
Published in Frontiers in aging neuroscience (01-07-2022)“…Background Patients with post-infective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) often show both short- and long-term cognitive deficits…”
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16
Inhibition of mannan-binding lectin associated serine protease (MASP)-2 reduces the cognitive deficits in a mouse model of severe traumatic brain injury
Published in Journal of neuroinflammation (28-05-2024)“…The lectin pathway (LP) of complement mediates inflammatory processes linked to tissue damage and loss of function following traumatic brain injury (TBI). LP…”
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17
Label-free monitoring of tissue biochemistry following traumatic brain injury using Raman spectroscopy
Published in Analyst (London) (01-01-2017)“…Traumatic brain injury (TBI) constitutes a major cause of death and long-term disability. At present, we lack methods to non-invasively track tissue…”
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18
Angiotensin-(1-7) as a Potential Therapeutic Strategy for Delayed Cerebral Ischemia in Subarachnoid Hemorrhage
Published in Frontiers in immunology (09-03-2022)“…Aneurysmal subarachnoid hemorrhage (SAH) is a substantial cause of mortality and morbidity worldwide. Moreover, survivors after the initial bleeding are often…”
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19
C. elegans detects toxicity of traumatic brain injury generated tau
Published in Neurobiology of disease (01-06-2021)“…Traumatic brain injury (TBI) is associated with widespread tau pathology in about 30% of patients surviving late after injury. We previously found that TBI in…”
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20
Chronic impact of traumatic brain injury on outcome and quality of life: a narrative review
Published in Critical care (London, England) (21-06-2016)“…Traditionally seen as a sudden, brutal event with short-term impairment, traumatic brain injury (TBI) may cause persistent, sometimes life-long, consequences…”
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