Search Results - "Zangara, Megan T"

Mediators of Metabolism: An Unconventional Role for NOD1 and NOD2 by Zangara, Megan T, Johnston, Isabel, Johnson, Erin E, McDonald, Christine

“…In addition to their classical roles as bacterial sensors, NOD1 and NOD2 have been implicated as mediators of metabolic disease. Increased expression of NOD1…”
Get full text

Maltodextrin Consumption Impairs the Intestinal Mucus Barrier and Accelerates Colitis Through Direct Actions on the Epithelium by Zangara, Megan T, Ponti, András K, Miller, Noah D, Engelhart, Morgan J, Ahern, Philip P, Sangwan, Naseer, McDonald, Christine

“…Food additives are common components of processed foods consumed in a Western diet. In inflammatory bowel disease patients, some diets that exclude food…”
Get full text

A 3D‐printable device allowing fast and reproducible longitudinal preparation of mouse intestines by DeLucia, Beckey, Samorezov, Sergey, Zangara, Megan T., Markley, Rachel L., Osborn, Lucas J., Schultz, Karlee B., McDonald, Christine, Claesen, Jan

“…Accurate and reproducible analysis of murine small and large intestinal tissue is key for preclinical models involving intestinal pathology. Currently, there…”
Get full text

Development of a reproducible porcine model of infected burn wounds by Al-Deen Said, Sayf, Jatana, Samreen, Ponti, András K, Johnson, Erin E, Such, Kimberly A, Zangara, Megan T, Madajka, Maria, Papay, Francis, McDonald, Christine

“…Severe burns are traumatic and physically debilitating injuries with a high rate of mortality. Bacterial infections often complicate burn injuries, which…”
Get full text

How diet and the microbiome shape health or contribute to disease: A mini-review of current models and clinical studies by Zangara, Megan T, McDonald, Christine

“…The human gut microbiome is a complex ecosystem of commensal microorganisms that help to shape host development and health. Host diet directly influences not…”
Get full text

Mouse Models of Intestinal Fibrosis by Li, Jiannan, Dejanovic, Dina, Zangara, Megan T, Chandra, Jyotsna, McDonald, Christine, Rieder, Florian

“…Mouse models are essential for investigation of underlying disease mechanisms that drive intestinal fibrosis, as well as assessment of potential therapeutic…”
Get more information

Characterizing the Pathogenic Potential of Crohn's Disease-Associated Adherent-Invasive Escherichia coli by Zangara, Megan T, Darwish, Lena, Coombes, Brian K

“…The microbiome of Crohn's disease (CD) patients is composed of a microbial community that is considered dysbiotic and proinflammatory in nature. The…”
Get full text

Impact of Diet on Inflammatory Bowel Disease Symptoms: An Adolescent Viewpoint by Zangara, Megan T, Bhesania, Natalie, Liu, Wei, Cresci, Gail A M, Kurowski, Jacob A, McDonald, Christine

“…Dietary modification shows promise as therapy in inflammatory bowel disease (IBD); however, it is unknown whether adolescents are interested in a dietary…”
Get full text

Mo1792 – Self-Reported Dietary Behaviors for Symptom Management of Inflammatory Bowel Disease in Adolescents by Zangara, Megan T., Bhesania, Natalie, Liu, Wei, Worley, Sarah, Cresci, Gail A., Kurowski, Jacob A., McDonald, Christine

Get full text

The Role of Diet as a Modifiable Factor of Inflammatory Bowel Disease Pathogenesis by Zangara, Megan T

“…Inflammatory bowel disease (IBD) is a chronic disease that causes relapsing inflammation in the gastrointestinal tract. Multiple risk factors have been…”
Get full text