Search Results - "Zang, Liqing"

Development of a Novel Zebrafish Model for Type 2 Diabetes Mellitus by Zang, Liqing, Shimada, Yasuhito, Nishimura, Norihiro

“…Obesity is a major cause of type 2 diabetes mellitus (T2DM) in mammals. We have previously established a zebrafish model of diet-induced obesity (DIO…”
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Effects of nanoplastic on toxicity of azole fungicides (ketoconazole and fluconazole) in zebrafish embryos by Bhagat, Jacky, Zang, Liqing, Nakayama, Hiroko, Nishimura, Norihiro, Shimada, Yasuhito

“…The ubiquity of nanoplastics (NPs) raises concerns about their interactions and combined toxicity with other common contaminants. Although azoles are present…”
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Application of omics approaches for assessing microplastic and nanoplastic toxicity in fish and seafood species by Bhagat, Jacky, Zang, Liqing, Nishimura, Norihiro, Shimada, Yasuhito

“…Numerous reports on the occurrence of microplastics/nanoplastics (MP/NP) in aquatic environments have triggered severe concerns about the adverse impact of…”
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Combined exposure to nanoplastics and metal oxide nanoparticles inhibits efflux pumps and causes oxidative stress in zebrafish embryos by Bhagat, Jacky, Zang, Liqing, Kaneco, Satoshi, Nishimura, Norihiro, Shimada, Yasuhito

“…The ubiquity of microplastic/nanoplastics (MP/NPs) provides an opportunity for their interaction with other widely spread environmental contaminants. MP/NP and…”
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Zebrafish as a Model for Obesity and Diabetes by Zang, Liqing, Maddison, Lisette A, Chen, Wenbiao

“…Obesity and diabetes now considered global epidemics. The prevalence rates of diabetes are increasing in parallel with the rates of obesity and the strong…”
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Evaluation of the Percutaneous Absorption of Drug Molecules in Zebrafish by Morikane, Daizo, Zang, Liqing, Nishimura, Norihiro

“…In recent decades, zebrafish ( ) has become a widely used vertebrate animal model for studying development and human diseases. However, studies on skin…”
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Transcriptome analysis of molecular response to UVC irradiation in zebrafish embryos by Zang, Liqing, Shimada, Yasuhito, Miyake, Hideto, Nishimura, Norihiro

“…Ultraviolet (UV) rays can be both harmful and beneficial to humans. This study aimed to investigate the toxicity and safety of ultraviolet C (UVC) exposure in…”
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The Hexane Extract of Citrus sphaerocarpa Ameliorates Visceral Adiposity by Regulating the PI3K/AKT/FoxO1 and AMPK/ACC Signaling Pathways in High-Fat-Diet-Induced Obese Mice by Zang, Liqing, Kagotani, Kazuhiro, Hayakawa, Takuya, Tsuji, Takehiko, Okumura, Katsuzumi, Shimada, Yasuhito, Nishimura, Norihiro

“…Obesity is an emerging global health issue with an increasing risk of disease linked to lifestyle choices. Previously, we reported that the hexane extract of…”
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Rhamnan sulphate from green algae Monostroma nitidum improves constipation with gut microbiome alteration in double-blind placebo-controlled trial by Shimada, Yasuhito, Terasawa, Masahiro, Okazaki, Fumiyoshi, Nakayama, Hiroko, Zang, Liqing, Nishiura, Kaoru, Matsuda, Koichi, Nishimura, Norihiro

“…Rhamnan sulphate (RS), a sulphated polysaccharide from Monostroma nitidum , possesses several biological properties that help in treating diseases such as…”
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Repeated Blood Collection for Blood Tests in Adult Zebrafish by Zang, Liqing, Shimada, Yasuhito, Nishimura, Yuhei, Tanaka, Toshio, Nishimura, Norihiro

“…Repeated blood collection is one of the most common techniques performed on laboratory animals. However, a non-lethal protocol for blood collection from…”
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Lacto-Fermented Cauliflower Fungus ( Sparassis crispa ) Ameliorates Hepatic Steatosis by Activating Beta-Oxidation in Diet-Induced Obese Zebrafish by Matsuura, Nobuo, Zang, Liqing, Nishimura, Norihiro, Shimada, Yasuhito

“…(SC), known as cauliflower mushroom, possesses a wide variety of health-promoting properties and a high content of -glucans. Its nutritional properties are…”
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Microbiome Alteration in Type 2 Diabetes Mellitus Model of Zebrafish by Okazaki, Fumiyoshi, Zang, Liqing, Nakayama, Hiroko, Chen, Zhen, Gao, Zi-Jun, Chiba, Hitoshi, Hui, Shu-Ping, Aoki, Takahiko, Nishimura, Norihiro, Shimada, Yasuhito

“…Understanding the gut microbiota in metabolic disorders, including type 2 diabetes mellitus (T2DM), is now gaining importance due to its potential role in…”
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A zebrafish model of diabetic nephropathy shows hyperglycemia, proteinuria and activation of the PI3K/Akt pathway by Zang, Liqing, Saitoh, Sei, Katayama, Kan, Zhou, Weibin, Nishimura, Norihiro, Shimada, Yasuhito

“…Diabetic nephropathy (DN), as a complication of diabetes, is a substantial healthcare challenge owing to the high risk of morbidity and mortality involved…”
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RNA-seq Based Transcriptome Analysis of the Anti-Obesity Effect of Green Tea Extract Using Zebrafish Obesity Models by Zang, Liqing, Shimada, Yasuhito, Nakayama, Hiroko, Kim, Youngil, Chu, Djong-Chi, Juneja, Lekh Raj, Kuroyanagi, Junya, Nishimura, Norihiro

“…Green tea is a popular beverage that is rich in polyphenolic compounds such as catechins. Its major content, (-)-epigallocatechin-3-gallate, has been shown to…”
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Lipidomic Profiling on Oxidized Phospholipids in Type 2 Diabetes Mellitus Model Zebrafish by CHEN, Zhen, ZANG, Liqing, WU, Yue, NAKAYAMA, Hiroko, SHIMADA, Yasuhito, SHRESTHA, Rojeet, ZHAO, Yaoyao, MIURA, Yusuke, CHIBA, Hitoshi, HUI, Shu-Ping, NISHIMURA, Norihiro

“…Type 2 diabetes mellitus is a serious metabolic disorder in the world. Oxidative stress, as a key role on the pathogenesis of diabetes, also results in the…”
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Anti-Obesity Natural Products Tested in Juvenile Zebrafish Obesogenic Tests and Mouse 3T3-L1 Adipogenesis Assays by Nakayama, Hiroko, Hata, Kanae, Matsuoka, Izumi, Zang, Liqing, Kim, Youngil, Chu, Djongchi, Juneja, Lekh Raj, Nishimura, Norihiro, Shimada, Yasuhito

“…(1) Background: The obesity epidemic has been drastically progressing in both children and adults worldwide. Pharmacotherapy is considered necessary for its…”
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Beneficial effects of seaweed-derived components on metabolic syndrome via gut microbiota modulation by Zang, Liqing, Baharlooeian, Maedeh, Terasawa, Masahiro, Shimada, Yasuhito, Nishimura, Norihiro

“…Metabolic syndrome comprises a group of conditions that collectively increase the risk of abdominal obesity, diabetes, atherosclerosis, cardiovascular…”
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Lecithin-Based Dermal Drug Delivery for Anti-Pigmentation Maize Ceramide by Kagotani, Kazuhiro, Nakayama, Hiroko, Zang, Liqing, Fujimoto, Yuki, Hayashi, Akihito, Sono, Ryoji, Nishimura, Norihiro, Shimada, Yasuhito

“…Ceramides have several well-known biological properties, including anti-pigmentation and anti-melanogenesis, which make them applicable for use in skincare…”
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Paraburkholderia sabiae administration alters zebrafish anxiety-like behavior via gut microbial taurine metabolism by Ichikawa, Shunsuke, Abe, Reimi, Fujimoto, Haruka, Higashi, Koushi, Zang, Liqing, Nakayama, Hiroko, Matsuoka, Izumi, Shimada, Yasuhito

“…Interventions to the gut microbiome manipulate the gut-brain axis and could be useful in the treatment of anxiety and depression. In this study, we…”
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Rhamnan sulphate from Monostroma nitidum attenuates hepatic steatosis by suppressing lipogenesis in a diet-induced obesity zebrafish model by Zang, Liqing, Shimada, Yasuhito, Tanaka, Toshio, Nishimura, Norihiro

“…•We examined effects of rhamnan sulphate on metabolic disorders in obese zebrafish.•Rhamnan sulphate ameliorated dyslipidaemia and hepatic steatosis.•Rhamnan…”
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