Search Results - "Zang, Jianye"
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Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis
Published in Nature chemical biology (01-12-2021)“…Spindle position control is essential for cell fate determination and organogenesis. Early studies indicate the essential role of the evolutionarily conserved…”
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Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein
Published in Nature communications (14-01-2019)“…Tetrathiomolybdate (TM) is used in the clinic for the treatment of Wilson’s disease by targeting the cellular copper efflux protein ATP7B (WLN). Interestingly,…”
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3
Imaging of Polar and Nonpolar Species Using Compact Desorption Electrospray Ionization/Postphotoionization Mass Spectrometry
Published in Analytical chemistry (Washington) (21-05-2019)“…Desorption electrospray ionization (DESI) mass spectrometry imaging (MSI) can simultaneously record the 2D distribution of polar biomolecules in tissue slices…”
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Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore
Published in Cell research (01-03-2018)Get full text
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Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation
Published in Nature chemical biology (01-04-2016)“…The cell cycle regulator CDK1 phosphorylates the acetyltransferase TIP60, which subsequently acetylates the mitotic regulator Aurora B to ensure chromosomal…”
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Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Published in The EMBO journal (20-07-2011)“…The SAGA (Spt–Ada–Gcn5 acetyltransferase) complex is an important chromatin modifying complex that can both acetylate and deubiquitinate histones. Sgf29 is a…”
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A Biosynthetic Route to Photoclick Chemistry on Proteins
Published in Journal of the American Chemical Society (27-10-2010)“…Light-induced chemical reactions exist in nature, regulating many important cellular and organismal functions, e.g., photosensing in prokaryotes and vision…”
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8
Systematic characterization of chromodomain proteins reveals an H3K9me1/2 reader regulating aging in C. elegans
Published in Nature communications (06-03-2023)“…The chromatin organization modifier domain (chromodomain) is an evolutionally conserved motif across eukaryotic species. The chromodomain mainly functions as a…”
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Centromere targeting of Mis18 requires the interaction with DNA and H2A–H2B in fission yeast
Published in Cellular and molecular life sciences : CMLS (01-01-2021)“…Faithful chromosome segregation during mitosis requires the correct assembly of kinetochore on the centromere. CENP-A is a variant of histone H3, which…”
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Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis
Published in Proceedings of the National Academy of Sciences - PNAS (12-12-2017)“…Kinetochores are superprotein complexes that orchestrate chromosome segregation via a dynamic interaction with spindle microtubules. A physical connection…”
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Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus
Published in Biotechnology letters (01-05-2020)“…Staphylococcus aureus is an anaerobic facultative microorganism that features the NreABC system for nitrate respiration. NreB is the sensor histidine kinase…”
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SIRT2 functions as a histone delactylase and inhibits the proliferation and migration of neuroblastoma cells
Published in Cell discovery (07-06-2022)Get full text
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13
Interaction of JMJD6 with single-stranded RNA
Published in Proceedings of the National Academy of Sciences - PNAS (17-08-2010)“…JMJD6 is a Jumonji C domain-containing hydroxylase. JMJD6 binds α-ketoglutarate and iron and has been characterized as either a histone arginine demethylase or…”
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Baicalein Acts against Candida albicans by Targeting Eno1 and Inhibiting Glycolysis
Published in Microbiology spectrum (31-08-2022)“…Baicalein (BE) is a promising antifungal small-molecule compound with an extended antifungal spectrum, good synergy with fluconazole, and low toxicity, but its…”
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Identification of Set11 from Staphylococcus aureus Mu50 strain as a ortholog of SSL7 via bioinformatic analysis and determination of its possible targets from human serum using CNBr-pull down assays
Published in Biotechnology letters (01-09-2017)“…Objectives To identify and characterize staphylococcus exotoxin-like (SET) protein Set11 from Staphylococcus aureus Mu50 strain and its possible targets…”
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Structural insights into human CCAN complex assembled onto DNA
Published in Cell discovery (09-09-2022)“…In mitosis, accurate chromosome segregation depends on kinetochores that connect centromeric chromatin to spindle microtubules. The centromeres of budding…”
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MIL-100(Al) Gels as an Excellent Platform Loaded with Doxorubicin Hydrochloride for pH-Triggered Drug Release and Anticancer Effect
Published in Nanomaterials (Basel, Switzerland) (19-06-2018)“…Slow and controlled release systems for drugs have attracted increasing interest recently. A highly efficient metal-organic gel (MOGs) drug delivery carrier,…”
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Structural basis of the recognition of a methylated histone tail by JMJD2A
Published in Proceedings of the National Academy of Sciences - PNAS (26-06-2007)“…The Jumonji C domain is a catalytic motif that mediates histone lysine demethylation. The Jumonji C-containing oxygenase JMJD2A specifically demethylates tri-…”
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Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1
Published in FEBS letters (17-02-2012)“…► Crystal structures of the human lamin B1 coil 2B and tail domains are presented. ► These two domains in lamin B1 adopt conserved folds to those of lamin A/C…”
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Staphylococcal superantigen-like protein 10 induces necroptosis through TNFR1 activation of RIPK3-dependent signal pathways
Published in Communications biology (12-08-2022)“…Staphylococcal aureus ( S. aureus ) infection can lead to a wide range of diseases such as sepsis and pneumonia. Staphylococcal superantigen-like (SSL)…”
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