Search Results - "Zandhuis, Nordin"

Regulation of IFN‐γ production by ZFP36L2 in T cells is time‐dependent by Zandhuis, Nordin D., Guislain, Aurélie, Popalzij, Abeera, Engels, Sander, Popović, Branka, Turner, Martin, Wolkers, Monika C.

“…CD8+ T cells kill target cells by releasing cytotoxic molecules and proinflammatory cytokines, such as TNF and IFN‐γ. The magnitude and duration of cytokine…”
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RNA-Binding Protein Expression Alters Upon Differentiation of Human B Cells and T Cells by Zandhuis, Nordin D, Nicolet, Benoit P, Wolkers, Monika C

“…B cells and T cells are key players in the defence against infections and malignancies. To exert their function, B cells and T cells differentiate into…”
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Sequence determinants as key regulators in gene expression of T cells by Nicolet, Benoit P., Zandhuis, Nordin D., Lattanzio, V. Maria, Wolkers, Monika C.

“…T cell homeostasis, T cell differentiation, and T cell effector function rely on the constant fine‐tuning of gene expression. To alter the T cell state,…”
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BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression by Grant, Francis M, Yang, Jie, Nasrallah, Rabab, Clarke, James, Sadiyah, Firas, Whiteside, Sarah K, Imianowski, Charlotte J, Kuo, Paula, Vardaka, Panagiota, Todorov, Tihomir, Zandhuis, Nordin, Patrascan, Ilinca, Tough, David F, Kometani, Kohei, Eil, Robert, Kurosaki, Tomohiro, Okkenhaug, Klaus, Roychoudhuri, Rahul

“…Regulatory T (Treg) cell populations are composed of functionally quiescent resting Treg (rTreg) cells which differentiate into activated Treg (aTreg) cells…”
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BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis by Imianowski, Charlotte J, Whiteside, Sarah K, Lozano, Teresa, Evans, Alexander C, Benson, Jayme D, Courreges, Christina J F, Sadiyah, Firas, Lau, Colleen M, Zandhuis, Nordin D, Grant, Francis M, Schuijs, Martijn J, Vardaka, Panagiota, Kuo, Paula, Soilleux, Elizabeth J, Yang, Jie, Sun, Joseph C, Kurosaki, Tomohiro, Okkenhaug, Klaus, Halim, Timotheus Y F, Roychoudhuri, Rahul

“…Natural killer (NK) cells are critical to immune surveillance against infections and cancer. Their role in immune surveillance requires that NK cells are…”
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The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function by Foskolou, Iosifina P., Cunha, Pedro P., Sánchez-López, Elena, Minogue, Eleanor A., Nicolet, Benoît P., Guislain, Aurélie, Jorgensen, Christian, Kostidis, Sarantos, Zandhuis, Nordin D., Barbieri, Laura, Bargiela, David, Nathanael, Demitris, Tyrakis, Petros A., Palazon, Asis, Giera, Martin, Wolkers, Monika C., Johnson, Randall S.

“…2-Hydroxyglutarate (2HG) is a byproduct of the tricarboxylic acid (TCA) cycle and is readily detected in the tissues of healthy individuals. 2HG is found in…”
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Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold by Vredevoogd, David W., Kuilman, Thomas, Ligtenberg, Maarten A., Boshuizen, Julia, Stecker, Kelly E., de Bruijn, Beaunelle, Krijgsman, Oscar, Huang, Xinyao, Kenski, Juliana C.N., Lacroix, Ruben, Mezzadra, Riccardo, Gomez-Eerland, Raquel, Yildiz, Mete, Dagidir, Ilknur, Apriamashvili, Georgi, Zandhuis, Nordin, van der Noort, Vincent, Visser, Nils L., Blank, Christian U., Altelaar, Maarten, Schumacher, Ton N., Peeper, Daniel S.

“…New opportunities are needed to increase immune checkpoint blockade (ICB) benefit. Whereas the interferon (IFN)γ pathway harbors both ICB resistance factors…”
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Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold by Vredevoogd, David W., Kuilman, Thomas, Ligtenberg, Maarten A., Boshuizen, Julia, Stecker, Kelly E., de Bruijn, Beaunelle, Krijgsman, Oscar, Huang, Xinyao, Kenski, Juliana C.N., Lacroix, Ruben, Mezzadra, Riccardo, Gomez-Eerland, Raquel, Yildiz, Mete, Dagidir, Ilknur, Apriamashvili, Georgi, Zandhuis, Nordin, van der Noort, Vincent, Visser, Nils L., Blank, Christian U., Altelaar, Maarten, Schumacher, Ton N., Peeper, Daniel S.

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