A molecular genome scan to identify DNA segments associated with live weight in Japanese quail

A molecular genome scan to identify DNA segments associated with live weight in Japanese quail

Japanese quail is an animal model in biological studies and also a commercial bird for eggs and meat production. This study was conducted to map quantitative trait loci (QTL) affecting live weight in Japanese quail. An F2 mapping population was developed by crossing two diverse lines (meat type and...

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Bibliographic Details
Published in:Molecular biology reports Vol. 43; no. 11; pp. 1267 - 1272
Main Authors: Iranmanesh, M., Esmailizadeh, A., Mohammad Abadi, M. R., Zand, Elmira, Mokhtari, M. S., Wu, Dong-Dong
Format: Journal Article
Language:English
Published: Dordrecht Springer Netherlands 01-11-2016
Springer Nature B.V
Subjects:
Animal Anatomy
Animal Biochemistry
Animals
Biomedical and Life Sciences
Body Weight - genetics
Breeding
Chromosome Mapping - methods
Coturnix - genetics
Coturnix japonica
Female
Genetic markers
Genome-Wide Association Study
Genotype
Genotype & phenotype
Histology
Life Sciences
Male
Microsatellite Repeats
Morphology
Original Article
Quantitative Trait Loci
Selective breeding
Weight
Wildfowl
QTL
Microsatellite markers
Body weight
Japanese quail
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Summary:Japanese quail is an animal model in biological studies and also a commercial bird for eggs and meat production. This study was conducted to map quantitative trait loci (QTL) affecting live weight in Japanese quail. An F2 mapping population was developed by crossing two diverse lines (meat type and egg layer) of Japanese quail. A total number of 34 F1 and 422 F2 progeny were produced by reciprocal crossing of eight pairs of parental birds. All the birds from three generations were genotyped for SSR markers that were spread across all the autosomal linkage groups. The studied traits were hatching weight and live weights at 1–5 weeks of age. QTL analysis was conducted by the regression interval mapping. Significant QTL were detected on chromosomes 1, 2, 3 (chromosome-wide significant) and 5 (genome-wide significant, P  < 0.05) for body weight. Although the additive effect of the detected QTL on chromosome 5 was significant, the dominance and imprinting effects were not significant. This finding is the first report of a genome-wide significant QTL associated with live weight in Japanese quail. Our results point out to candidate DNA regions affecting live weight, a trait of great economic relevance to the Japanese quail breeding. Although these results enhance our current knowledge about the genetic control of live weight in the Japanese quail, it should be noted that the initial QTL results from the experimental designs such as backcross or F2 cannot be applied directly to the breeding programs and require further validation within the commercial lines.
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ISSN:0301-4851
1573-4978
DOI:10.1007/s11033-016-4059-y