Search Results - "Zanchin, Nilson T."
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Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs
Published in PLoS neglected tropical diseases (01-06-2019)“…Dogs are considered sentinels in areas of Trypanosoma cruzi transmission risk to humans. ELISA is generally the method of choice for diagnosing T. cruzi…”
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A draft of the human septin interactome
Published in PloS one (02-11-2010)“…Septins belong to the GTPase superclass of proteins and have been functionally implicated in cytokinesis and the maintenance of cellular morphology. They are…”
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The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processing
Published in PloS one (16-12-2011)“…NIP7 is one of the many trans-acting factors required for eukaryotic ribosome biogenesis, which interacts with nascent pre-ribosomal particles and dissociates…”
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InP Nanowire Biosensor with Tailored Biofunctionalization: Ultrasensitive and Highly Selective Disease Biomarker Detection
Published in Nano letters (11-10-2017)“…Electrically active field-effect transistors (FET) based biosensors are of paramount importance in life science applications, as they offer direct, fast, and…”
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5
Active ingredients against human epidermal aging
Published in Ageing research reviews (01-05-2014)“…Highlights • Epidermis and the evolution toward a global understanding of skin aging. • Molecular, cell-related, and morphological changes in aged epidermis. •…”
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Proteomic Characterization of the Human FTSJ3 Preribosomal Complexes
Published in Journal of proteome research (01-06-2012)“…In eukaryotes, ribosome biogenesis involves excision of transcribed spacer sequences from the preribosomal RNA, base and ribose covalent modification at…”
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NIP7 protein is required for accurate pre-rRNA processing in human cells
Published in Nucleic acids research (01-01-2011)“…Eukaryotic ribosome biogenesis requires the function of a large number of trans-acting factors which interact transiently with the nascent pre-rRNA and…”
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Insights into the Mechanism of Progressive RNA Degradation by the Archaeal Exosome
Published in The Journal of biological chemistry (16-05-2008)“…Initially identified in yeast, the exosome has emerged as a central component of the RNA maturation and degradation machinery both in Archaea and eukaryotes…”
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Functional EGF domain of the human neuregulin 1α produced in Escherichia coli with accurate disulfide bonds
Published in Molecular biology reports (01-12-2022)“…Background Neuregulins comprise a large family of growth factors containing an epidermal growth factor (EGF) domain. NRG1 acts in signaling pathways involved…”
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The essential nucleolar yeast protein Nop8p controls the exosome function during 60S ribosomal subunit maturation
Published in PloS one (29-06-2011)“…The yeast nucleolar protein Nop8p has previously been shown to interact with Nip7p and to be required for 60S ribosomal subunit formation. Although depletion…”
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Development of a New Lateral Flow Assay Based on IBMP-8.1 and IBMP-8.4 Chimeric Antigens to Diagnose Chagas Disease
Published in BioMed research international (2020)“…Despite several available methodologies for Chagas disease (CD) serological screening, the main limitation of chronic CD diagnosis is the lack of effective…”
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Post-translational Modifications of Trypanosoma cruzi Canonical and Variant Histones
Published in Journal of proteome research (03-03-2017)“…Chagas disease, caused by Trypanosoma cruzi, still affects millions of people around the world. No vaccines nor treatment for chronic Chagas disease are…”
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Development of an anti‐SARS‐CoV‐2 monoclonal antibody panel and its applicability as a reagent in high‐throughput fluorescence reduction neutralization and immunohistochemistry assays
Published in Journal of medical virology (01-09-2023)“…Abstract Since its emergence in late 2019, coronavirus disease 2019 (COVID‐19) has caused millions of deaths and socioeconomic losses. Although vaccination…”
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Assessment of Cross-Reactivity of Chimeric Trypanosoma cruzi Antigens with Crithidia sp. LVH-60A: Implications for Accurate Diagnostics
Published in Diagnostics (Basel) (01-11-2023)“…This study focuses on developing accurate immunoassays for diagnosing Chagas disease (CD), a challenging task due to antigenic similarities between Trypanosoma…”
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Looking over Toxin–K+ Channel Interactions. Clues from the Structural and Functional Characterization of α-KTx Toxin Tc32, a Kv1.3 Channel Blocker
Published in Biochemistry (Easton) (06-03-2012)“…α-KTx toxin Tc32, from the Amazonian scorpion Tityus cambridgei, lacks the dyad motif, including Lys27, characteristic of the family and generally associated…”
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A Time-Based and Intratumoral Proteomic Assessment of a Recurrent Glioblastoma Multiforme
Published in Frontiers in oncology (22-08-2016)“…Tumors consist of cells in different stages of transformation with molecular and cellular heterogeneity. By far, heterogeneity is the hallmark of glioblastoma…”
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The Shwachman–Bodian–Diamond syndrome associated protein interacts with HsNip7 and its down-regulation affects gene expression at the transcriptional and translational levels
Published in Experimental cell research (10-12-2007)“…The Shwachman–Bodian–Diamond syndrome (SDS) is an autosomal disorder with pleiotropic phenotypes including pancreatic, skeletal and bone marrow deficiencies…”
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Structure, Dynamics, and RNA Interaction Analysis of the Human SBDS Protein
Published in Journal of molecular biology (05-03-2010)“…Shwachman–Bodian–Diamond syndrome is an autosomal recessive genetic syndrome with pleiotropic phenotypes, including pancreatic deficiencies, bone marrow…”
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Structural Insights into the Interaction of the Nip7 PUA Domain with Polyuridine RNA
Published in Biochemistry (Easton) (11-12-2007)“…The conserved protein Nip7 is involved in ribosome biogenesis, being required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly in…”
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The impact of blood-processing time on the proteome of human peripheral blood mononuclear cells
Published in Biochimica et biophysica acta. Proteins and proteomics (01-03-2021)“…Human peripheral blood mononuclear cells (PBMC) are key to several diagnostics assays and basic science research. Blood pre-analytical variations that occur…”
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