Search Results - "Zanatta, Daniela B."
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Mesenchymal bone marrow stem cells within polyglycolic acid tube observed in vivo after six weeks enhance facial nerve regeneration
Published in Brain research (13-05-2013)“…Abstract Autografting is the gold-standard method for facial nerve repair with tissue loss. Its association with high-quality scaffolds and cell implants has…”
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Bone marrow stem cells in facial nerve regeneration from isolated stumps
Published in Muscle & nerve (01-09-2013)“…ABSTRACT Introduction Severe lesions in the facial nerve may have extensive axonal loss and leave isolated stumps that impose technical difficulties for nerve…”
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Activation of endogenous p53 by combined p19Arf gene transfer and nutlin-3 drug treatment modalities in the murine cell lines B16 and C6
Published in BMC cancer (22-06-2010)“…Reactivation of p53 by either gene transfer or pharmacologic approaches may compensate for loss of p19Arf or excess mdm2 expression, common events in melanoma…”
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PDIA1 acts as master organizer of NOX1/NOX4 balance and phenotype response in vascular smooth muscle
Published in Free radical biology & medicine (01-01-2021)“…Changes in vascular smooth muscle cell (VSMC) phenotype underlie disease pathophysiology and are strongly regulated by NOX NADPH oxidases, with NOX1 favoring…”
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Genetic barcode sequencing for screening altered population dynamics of hematopoietic stem cells transduced with lentivirus
Published in Molecular therapy. Methods & clinical development (01-01-2014)“…Insertional mutagenesis has been associated with malignant cell transformation in gene therapy protocols, leading to discussions about vector security…”
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TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1) stable silencing increases late apoptosis by upregulation of caspase 9 and APAF1 in RPMI8226 multiple myeloma cell line
Published in Biochimica et biophysica acta (01-06-2016)“…TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1) modulates apoptotic pathways preventing the formation of the apoptosome complex. Our group previous study…”
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Proteasome and heat shock protein 70 (HSP70) inhibitors as therapeutic alternative in multiple myeloma
Published in Oncotarget (29-12-2017)“…HSP70 connects multiple signaling pathways that work synergistically to protect tumor cells from death by proteotoxic stress and represents a possible target…”
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Reestablishment of p53/Arf and interferon-β pathways mediated by a novel adenoviral vector potentiates antiviral response and immunogenic cell death
Published in Cell death discovery (01-01-2017)“…Late stage melanoma continues to be quite difficult to treat and new therapeutic approaches are needed. Since these tumors often retain wild-type p53 and have…”
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Evaluation of economically important traits from sixteen parental strains of the silkworm Bombyx mori L (Lepidoptera: Bombycidae)
Published in Neotropical entomology (01-05-2009)“…The classification and characterization of silkworm strains are important for sericulture, which is supported by the constant development of new hybrids. In…”
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Abstract 3539: Modifications of adenoviral structure and genome improves transduction efficiency and transgene expression
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Innovative strategies are required for cancer treatment, especially evident given that many patients relapse or do not respond to current therapeutics…”
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Abstract 264: Protein Disulfide Isomerase A1 is a Central Hub for Redox Regulation of VSMC Phenotype
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2017)“…Abstract only Objective: Vascular smooth muscle cell (VSMC) phenotype switch depends on extrinsic/intrinsic cues including NOX NADPH oxidase-linked redox…”
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Abstract 1236: Combined transfer of p19Arf and interferon-beta genes to mouse melanoma cells causes LC3B- and caspase-3-independent cell death and alters the expression of critical genes
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Tumors cells are able to resist cell death and evade the immune system. This resistance can be caused by alterations in Trp53 itself or p19Arf loss and the…”
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Abstract 1017: Silencing of apoptosome regulating genes, HSP70 and TRIAP1, induces apoptosis in MM cell lines
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Introduction: Some evidences suggest that heat shock protein 70 (HSP70) is overexpressed in many types of cancer, providing a selective advantage for tumor…”
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