Search Results - "Zanaboni, Anna"
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Endocannabinoid System and Migraine Pain: An Update
Published in Frontiers in neuroscience (19-03-2018)“…The trigeminovascular system (TS) activation and the vasoactive release from trigeminal endings, in proximity of the meningeal vessels, are considered two of…”
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Influence of body variables in the development of metabolic syndrome-A long term follow-up study
Published in PloS one (12-02-2018)“…The body variable associated with the diagnosis of Metabolic Syndrome (MetS) is an elevated waist circumference (WC), although a number of other variables have…”
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Nitroglycerin as a comparative experimental model of migraine pain: From animal to human and back
Published in Progress in neurobiology (01-06-2019)“…Migraine is a disease for which there is still no defined pathophysiological etiology and few translational models. The organic nitrate nitroglycerin has been…”
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Assessment of right ventricular function by feature-tracking echocardiography in conscious healthy dogs
Published in Research in veterinary science (01-04-2016)“…Advanced two-dimensional echocardiographic techniques allow strain (S) analysis of regional function and thus can provide information on regional myocardial…”
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FAAH inhibition as a preventive treatment for migraine: A pre-clinical study
Published in Neurobiology of disease (01-02-2020)“…Fatty-acid amide hydrolase (FAAH) is an intracellular serine hydrolase that catalyzes the cleavage of endogenous fatty-acid amides, including the…”
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Chronic and intermittent administration of systemic nitroglycerin in the rat induces an increase in the gene expression of CGRP in central areas: potential contribution to pain processing
Published in Journal of headache and pain (13-07-2018)“…Background Calcitonin gene related peptide (CGRP) is a key neuropeptide involved in the activation of the trigeminovascular system and it is likely related to…”
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Modulation of Glia Activation by TRPA1 Antagonism in Preclinical Models of Migraine
Published in International journal of molecular sciences (15-11-2022)“…Preclinical data point to the contribution of transient receptor potential ankyrin 1 (TRPA1) channels to the complex mechanisms underlying migraine pain. TRPA1…”
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A Narrative Review of Intestinal Microbiota's Impact on Migraine with Psychopathologies
Published in International journal of molecular sciences (17-06-2024)“…Migraine is a common and debilitating neurological disorder characterized by the recurrent attack of pulsating headaches typically localized on one side of the…”
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CD163 as a Potential Biomarker of Monocyte Activation in Ischemic Stroke Patients
Published in International journal of molecular sciences (01-07-2021)“…In ischemic stroke patients, a higher monocyte count is associated with disease severity and worse prognosis. The complex correlation between subset phenotypes…”
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Plasma levels of CGRP and expression of specific microRNAs in blood cells of episodic and chronic migraine subjects: towards the identification of a panel of peripheral biomarkers of migraine?
Published in Journal of headache and pain (16-10-2020)“…Background Migraine can manifest with an episodic or a chronic pattern in a continuum of disease severity. Multiple factors are associated with the progression…”
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Antagonism of CGRP Receptor: Central and Peripheral Mechanisms and Mediators in an Animal Model of Chronic Migraine
Published in Cells (Basel, Switzerland) (30-09-2022)“…Calcitonin-gene-related peptide (CGRP) plays a key role in migraine pathophysiology and more specifically in the mechanisms underlying peripheral and central…”
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Activity of FAAH-Inhibitor JZP327A in an Experimental Rat Model of Migraine
Published in International journal of molecular sciences (01-06-2023)“…Increased anandamide levels via fatty acid amide hydrolase (FAAH) inhibition can decrease the pronociceptive responses and inflammatory mediators in animal…”
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Biomarkers of Migraine: An Integrated Evaluation of Preclinical and Clinical Findings
Published in International journal of molecular sciences (01-03-2023)“…In recent years, numerous efforts have been made to identify reliable biomarkers useful in migraine diagnosis and progression or associated with the response…”
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URB937 Prevents the Development of Mechanical Allodynia in Male Rats with Trigeminal Neuralgia
Published in Pharmaceuticals (Basel, Switzerland) (01-11-2023)“…Cannabinoids are proposed for alleviating neuropathic pain, but their use is limited by cannabimimetic side effects. The inhibition of the fatty acid amide…”
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Antagonism of Transient Receptor Potential Ankyrin Type-1 Channels as a Potential Target for the Treatment of Trigeminal Neuropathic Pain: Study in an Animal Model
Published in International journal of molecular sciences (25-10-2018)“…Transient receptor potential ankyrin type-1 (TRPA1) channels are known to actively participate in different pain conditions, including trigeminal neuropathic…”
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Characterization of the Involvement of Tumour Necrosis Factor (TNF)-α-Stimulated Gene 6 (TSG-6) in Ischemic Brain Injury Caused by Middle Cerebral Artery Occlusion in Mouse
Published in International journal of molecular sciences (18-03-2023)“…The identification of novel targets to modulate the immune response triggered by cerebral ischemia is crucial to promote the development of effective stroke…”
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The role of the transient receptor potential ankyrin type-1 (TRPA1) channel in migraine pain: evaluation in an animal model
Published in Journal of headache and pain (07-09-2017)“…Background Clinical and experimental studies have pointed to the possible involvement of the transient receptor potential ankyrin type-1 (TRPA1) channels in…”
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Dual Inhibition of FAAH and MAGL Counteracts Migraine-like Pain and Behavior in an Animal Model of Migraine
Published in Cells (Basel, Switzerland) (26-09-2021)“…The endocannabinoid system exerts an important role in pain processing and modulation. Modulation of the system with hydrolase inhibitors of anandamide (AEA)…”
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Potentiation of endocannabinoids and other lipid amides prevents hyperalgesia and inflammation in a pre-clinical model of migraine
Published in Journal of headache and pain (01-12-2022)“…Targeting fatty acid amide hydrolase (FAAH) is a promising therapeutic strategy to combat certain forms of pain, including migraine headache. FAAH inhibitors,…”
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Intranasal administration of recombinant human BDNF as a potential therapy for some primary headaches
Published in Journal of headache and pain (25-10-2024)“…Background In addition to its critical role in neurogenesis, brain-derived neurotrophic factor (BDNF) modulates pain and depressive behaviors. Methods In a…”
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