Search Results - "Zamudio, Stacy"

Differentiation of first trimester cytotrophoblast to extravillous trophoblast involves an epithelial–mesenchymal transition by DaSilva-Arnold, Sonia, James, Joanna L, Al-Khan, Abdulla, Zamudio, Stacy, Illsley, Nicholas P

“…Abstract The transformation of cytotrophoblast (CTB) to extravillous trophoblast (EVT) is an essential process for placental implantation. EVT generated at the…”
Get full text

Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development by Ilekis, John V., PhD, Tsilou, Ekaterini, MD, Fisher, Susan, PhD, Abrahams, Vikki M., PhD, Soares, Michael J., PhD, Cross, James C., PhD, Zamudio, Stacy, PhD, Illsley, Nicholas P., DPhil, Myatt, Leslie, PhD, Colvis, Christine, PhD, Costantine, Maged M., MD, Haas, David M., MD, Sadovsky, Yoel, MD, Weiner, Carl, MD, Rytting, Erik, PhD, Bidwell, Gene, PhD

“…Although much progress is being made in understanding the molecular pathways in the placenta that are involved in the pathophysiology of pregnancy-related…”
Get full text

Human trophoblast epithelial-mesenchymal transition in abnormally invasive placenta by DaSilva-Arnold, Sonia C, Zamudio, Stacy, Al-Khan, Abdulla, Alvarez-Perez, Jesus, Mannion, Ciaran, Koenig, Christopher, Luke, Davlyn, Perez, Anisha M, Petroff, Margaret, Alvarez, Manuel, Illsley, Nicholas P

“…Differentiation of first trimester human placental cytotrophoblast (CTB) from an anchoragedependent epithelial phenotype into the mesenchymal-like invasive…”
Get full text

Customizing EV-CATCHER to Purify Placental Extracellular Vesicles from Maternal Plasma to Detect Placental Pathologies by Mitchell, Megan I, Khalil, Marwa, Ben-Dov, Iddo Z, Alverez-Perez, Jesus, Illsley, Nicholas P, Zamudio, Stacy, Al-Khan, Abdulla, Loudig, Olivier

“…Placenta Accreta Spectrum (PAS) is a life-threatening condition in which placental trophoblastic cells abnormally invade the uterus, often up to the uterine…”
Get full text

Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1 by Nevo, Ori, Soleymanlou, Nima, Wu, Yuan, Xu, Jing, Kingdom, John, Many, Ariel, Zamudio, Stacy, Caniggia, Isabella

“…Elevated expression of soluble vascular endothelial growth factor receptor-1 (sFlt-1) in preeclampsia plays a major role in the pathogenesis of this serious…”
Get more information

ZEB2, a master regulator of the epithelial–mesenchymal transition, mediates trophoblast differentiation by DaSilva-Arnold, Sonia C, Kuo, Che-Ying, Davra, Viralkumar, Remache, Yvonne, Kim, Peter C W, Fisher, John P, Zamudio, Stacy, Al-Khan, Abdulla, Birge, Raymond B, Illsley, Nicholas P

“…Abstract STUDY QUESTION Does the upregulation of the zinc finger E-box binding homeobox 2 (ZEB2) transcription factor in human trophoblast cells lead to…”
Get full text

Regulation of human trophoblast GLUT1 glucose transporter by insulin-like growth factor I (IGF-I) by Baumann, Marc U, Schneider, Henning, Malek, Antoine, Palta, Vidya, Surbek, Daniel V, Sager, Ruth, Zamudio, Stacy, Illsley, Nicholas P

“…Glucose transport to the fetus across the placenta takes place via glucose transporters in the opposing faces of the barrier layer, the microvillous and basal…”
Get full text

Increased incidence of respiratory distress syndrome in neonates of mothers with abnormally invasive placentation by Spillane, Nicole T, Zamudio, Stacy, Alvarez-Perez, Jesus, Andrews, Tracy, Nyirenda, Themba, Alvarez, Manuel, Al-Khan, Abdulla

“…The incidence of abnormally invasive placentation (AIP) is increasing. Most of these pregnancies are delivered preterm. We sought to characterize neonatal…”
Get full text

Decreased Vitamin D Levels and Altered Placental Vitamin D Gene Expression at High Altitude: Role of Genetic Ancestry by Mata-Greenwood, Eugenia, Westenburg, Hans C A, Zamudio, Stacy, Illsley, Nicholas P, Zhang, Lubo

“…High-altitude hypoxia challenges reproduction; particularly in non-native populations. Although high-altitude residence is associated with vitamin D…”
Get full text

Molecular Evidence of Placental Hypoxia in Preeclampsia by Soleymanlou, Nima, Jurisica, Igor, Nevo, Ori, Ietta, Francesca, Zhang, Xin, Zamudio, Stacy, Post, Martin, Caniggia, Isabella

“…Background: Oxygen plays a central role in human placental pathologies including preeclampsia, a leading cause of fetal and maternal death and morbidity…”
Get full text

Hypoglycemia and the origin of hypoxia-induced reduction in human fetal growth by Zamudio, Stacy, Torricos, Tatiana, Fik, Ewa, Oyala, Maria, Echalar, Lourdes, Pullockaran, Janet, Tutino, Emily, Martin, Brittney, Belliappa, Sonia, Balanza, Elfride, Illsley, Nicholas P

“…The most well known reproductive consequence of residence at high altitude (HA >2700 m) is reduction in fetal growth. Reduced fetoplacental oxygenation is an…”
Get full text

Hypoxic upregulation of glucose transporters in BeWo choriocarcinoma cells is mediated by hypoxia-inducible factor-1 by Baumann, Marc U, Zamudio, Stacy, Illsley, Nicholas P

“…Placental hypoxia has been implicated in pregnancy pathologies, including fetal growth restriction and preeclampsia; however, the mechanism by which the…”
Get more information

Application of a novel mass spectrometric (MS) method to examine exposure to Bisphenol-A and common substitutes in a maternal fetal cohort by Ihde, Erin Speiser, Zamudio, Stacy, Loh, Ji Meng, Zhu, Yalin, Woytanowski, John, Rosen, Lawrence, Liu, Min, Buckley, Brian

“…The use of Bisphenol A (BPA) has widely been replaced in consumer products by analogs BPB, BPE, BPF, BPS, and BPAF. Recent studies have linked these…”
Get full text

Where the O2 goes to: preservation of human fetal oxygen delivery and consumption at high altitude by Postigo, Lucrecia, Heredia, Gladys, Illsley, Nicholas P., Torricos, Tatiana, Dolan, Caitlin, Echalar, Lourdes, Tellez, Wilma, Maldonado, Ivan, Brimacombe, Michael, Balanza, Elfride, Vargas, Enrique, Zamudio, Stacy

“…Fetal growth is decreased at high altitude (> 2700 m). We hypothesized that variation in fetal O 2 delivery might account for both the altitude effect and the…”
Get full text

DECIDE to sleep on your side: novel MRI approach unmasks phenomena relevant to stillbirth by Zamudio, Stacy

Get full text

Lipid profile of circulating placental extracellular vesicles during pregnancy identifies foetal growth restriction risk by Klemetti, Miira M., Pettersson, Ante B. V., Ahmad Khan, Aafaque, Ermini, Leonardo, Porter, Tyler R., Litvack, Michael L., Alahari, Sruthi, Zamudio, Stacy, Illsley, Nicholas P., Röst, Hannes, Post, Martin, Caniggia, Isabella

“…Small‐for‐gestational age (SGA) neonates exhibit increased perinatal morbidity and mortality, and a greater risk of developing chronic diseases in adulthood…”
Get full text

Ancestry dependent balancing selection of placental dysferlin at high-altitude by Gundling, Jr, William E, Post, Sasha, Illsley, Nicholas P, Echalar, Lourdes, Zamudio, Stacy, Wildman, Derek E

“…The placenta mediates fetal growth by regulating gas and nutrient exchange between the mother and the fetus. The cell type in the placenta where this nutrient…”
Get full text

Preoperative cystoscopy could determine the severity of placenta accreta spectrum disorders: An observational study by Al‐Khan, Abdulla, Guirguis, George, Zamudio, Stacy, Alvarez, Manuel, Martimucci, Kristina, Luke, Davlyn, Alvarez‐Perez, Jesus

“…Aim In the surgical treatment of placenta accreta spectrum disorders, cystoscopy for prophylactic stent placement is performed to protect the ureters from…”
Get full text

Maternal oxygen delivery is not related to altitude- and ancestry-associated differences in human fetal growth by Zamudio, Stacy, Postigo, Lucrecia, Illsley, Nicholas P., Rodriguez, Carmelo, Heredia, Gladys, Brimacombe, Michael, Echalar, Lourdes, Torricos, Tatiana, Tellez, Wilma, Maldonado, Ivan, Balanza, Elfride, Alvarez, Tatiana, Ameller, Julio, Vargas, Enrique

“…Fetal growth is reduced at high altitude, but the decrease is less among long-resident populations. We hypothesized that greater maternal uteroplacental O 2…”
Get full text

Prophylactic Hypogastric Artery Ligation during Placenta Percreta Surgery: A Retrospective Cohort Study by Kuhn, Theresa, Martimucci, Kristina, Al-Khan, Abdulla, Bilinski, Robyn, Zamudio, Stacy, Alvarez-Perez, Jesus

“…Abstract Objective  To evaluate if prophylactic hypogastric artery ligation (HAL) decreases surgical blood loss and blood products transfused. Study Design …”
Get full text