Search Results - "Zamudio, Sergio R."
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Thalidomide Attenuates Epileptogenesis and Seizures by Decreasing Brain Inflammation in Lithium Pilocarpine Rat Model
Published in International journal of molecular sciences (30-03-2023)“…Thalidomide (TAL) has shown potential therapeutic effects in neurological diseases like epilepsy. Both clinical and preclinical studies show that TAL may act…”
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Changes in the Dentate Gyrus Gene Expression Profile Induced by Levetiracetam Treatment in Rats with Mesial Temporal Lobe Epilepsy
Published in International journal of molecular sciences (01-02-2024)“…Temporal lobe epilepsy (TLE) is one of the most common forms of focal epilepsy. Levetiracetam (LEV) is an antiepileptic drug whose mechanism of action at the…”
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Antidepressant effects of acupoint stimulation and fluoxetine by increasing dendritic arborization and spine density in CA1 hippocampal neurons of socially isolated rats
Published in Neuroscience letters (14-05-2018)“…•Chronic social isolation (SI) elicits depressive-like behaviors in male rats.•Chronic SI induces atrophy of pyramidal neuronal in CA1 hippocampus region…”
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Levetiracetam Mechanisms of Action: From Molecules to Systems
Published in Pharmaceuticals (Basel, Switzerland) (13-04-2022)“…Epilepsy is a chronic disease that affects millions of people worldwide. Antiepileptic drugs (AEDs) are used to control seizures. Even though parts of their…”
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Levetiracetam Reduced the Basal Excitability of the Dentate Gyrus without Restoring Impaired Synaptic Plasticity in Rats with Temporal Lobe Epilepsy
Published in Brain sciences (01-09-2020)“…Temporal lobe epilepsy (TLE), the most common type of focal epilepsy, affects learning and memory; these effects are thought to emerge from changes in synaptic…”
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Antidepressant-like effects of acupuncture via modulation of corticosterone, sex hormones, and hippocampal BDNF expression in male rats
Published in Brain research bulletin (01-08-2021)“…•Acupuncture produces antidepressant-like effects in social isolated rats.•Acupuncture recovers normal BDNF hippocampal levels in rats subjected to social…”
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Cerebrolysin enhances the expression of the synaptogenic protein LRRTM4 in the hippocampus and improves learning and memory in senescent rats
Published in Behavioural pharmacology (01-08-2020)“…Aging reduces the efficiency of the organs and systems, including the cognitive functions. Brain aging is related to a decrease in the vascularity,…”
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Subchronic cerebrolysin treatment alleviates cognitive impairments and dendritic arborization alterations of granular neurons in the hippocampal dentate gyrus of rats with temporal lobe epilepsy
Published in Epilepsy & behavior (01-08-2019)“…Temporal lobe epilepsy (TLE) is one of the most frequent forms of focal epilepsy; patients with this condition, in addition to exhibiting complex seizures,…”
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Neonatal ventral hippocampus lesion disrupts maternal behavior in rats: An animal model of schizophrenia
Published in Developmental psychobiology (01-09-2022)“…Although individuals with schizophrenia typically present deficits in social interaction, little is known about the quality of their parent–infant…”
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Effect of melatonin injection into the periaqueductal gray on antinociception and tonic immobility in male rats
Published in Hormones and behavior (01-03-2017)“…Melatonin (MLT) is a neurohormone with significant involvement in several biological functions, of which antinociception and tonic immobility (TI) may be the…”
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The high-fructose intake of dams during pregnancy and lactation exerts sex-specific effects on adult rat offspring metabolism
Published in Journal of developmental origins of health and disease (01-06-2021)“…Experimental studies have demonstrated the effects of maternal fructose consumption during pregnancy and lactation on metabolic alterations in their offspring,…”
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Corticosterone microinjected into nucleus pontis oralis increases tonic immobility in rats
Published in Hormones and behavior (01-09-2011)“…Tonic immobility (TI) is also known as “immobility response”, “immobility reflex”, “animal hypnosis”, etc. It is an innate antipredatory behavior characterized…”
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The effects of acute stress and acute corticosterone administration on the immobility response in rats
Published in Brain research bulletin (16-12-2009)“…Abstract The immobility response is an innate antipredatory behavior in a broad variety of species. The immobility response varies in its postural components…”
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Immobility response elicited by clamping the neck induces antinociception in a “tonic pain” test in mice
Published in Life sciences (1973) (08-08-2006)“…Clamping the neck followed by body inversion to a supine position in mice elicits an immobility response called immobility by clamping the neck (ICN). The…”
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Sub-Chronic Cerebrolysin Treatment Attenuates the Long-lasting Behavioral Alterations Caused by Maternal Separation in Rats
Published in International journal of pharmacology (15-11-2014)Get full text
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Differential Effect of the Dopamine D3 Agonist (±)-7-Hydroxy-2-(N,N-di-n-propylamino) Tetralin (7-OH-DPAT) on Motor Activity between Adult Wistar and Sprague-Dawley Rats after a Neonatal Ventral Hippocampus Lesion
Published in International Journal of Medicinal Chemistry (Online) (01-01-2011)“…The neonatal ventral hippocampal lesion (nVHL) has been widely used as an animal model for schizophrenia. Rats with an nVHL show several delayed behavioral…”
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Differential effect of testosterone and repetitive induction on cataleptic and dorsal immobility in mice
Published in Hormones and behavior (01-06-2006)“…In nature, many species under conditions of stress (e.g., predator attack, pups carried by the mother, mating) show immobility states called “immobility…”
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Differential Effect of the Dopamine D 3 Agonist ( ± )-7-Hydroxy-2-(N,N-di- n -propylamino) Tetralin (7-OH-DPAT) on Motor Activity between Adult Wistar and Sprague-Dawley Rats after a Neonatal Ventral Hippocampus Lesion
Published in International Journal of Medicinal Chemistry (Online) (01-12-2011)“…The neonatal ventral hippocampal lesion (nVHL) has been widely used as an animal model for schizophrenia. Rats with an nVHL show several delayed behavioral…”
Get full text
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