Search Results - "Zampighi, Guido A."

A novel synaptic vesicle fusion path in the rat cerebral cortex: the "saddle" point hypothesis by Zampighi, Guido A, Serrano, Raul, Vergara, Julio L

“…We improved freeze-fracture electron microscopy to study synapses in the neuropil of the rat cerebral cortex at ∼2 nm resolution and in three-dimensions. In…”
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Conical tomography of a ribbon synapse: structural evidence for vesicle fusion by Zampighi, Guido A, Schietroma, Cataldo, Zampighi, Lorenzo M, Woodruff, Michael, Wright, Ernest M, Brecha, Nicholas C

“…To characterize the sites of synaptic vesicle fusion in photoreceptors, we evaluated the three-dimensional structure of rod spherules from mice exposed to…”
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The three-dimensional distribution of αA-crystalline in rat lenses and its possible relation to transparency by Zampighi, Guido A, Zampighi, Lorenzo, Lanzavecchia, Salvatore

“…Lens transparency depends on the accumulation of massive quantities (600-800 mg/ml) of twelve primary crystallines and two truncated crystallines in highly…”
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Structural Analysis of Cloned Plasma Membrane Proteins by Freeze-Fracture Electron Microscopy by Eskandari, Sepehr, Wright, Ernest M., Kreman, Mike, Starace, Dorine M., Zampighi, Guido A.

“…We have used freeze-fracture electron microscopy to examine the oligomeric structure and molecular asymmetry of integral plasma membrane proteins. Recombinant…”
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Epithelial Organization of the Mammalian Lens by Zampighi, Guido A, Eskandari, Sepehr, Kreman, Michael

“…To understand the structural organization responsible for lens function, we have studied the three-dimensional arrangement of cells in the lens, and the…”
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Pentameric Assembly of a Neuronal Glutamate Transporter by Eskandari, Sepehr, Kreman, Michael, Kavanaugh, Michael P., Wright, Ernest M., Zampighi, Guido A.

“…Freeze-fracture electron microscopy was used to study the structure of a human neuronal glutamate transporter (EAAT3). EAAT3 was expressed in Xenopus laevis…”
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Conical Electron Tomography of a Chemical Synapse: Polyhedral Cages Dock Vesicles to the Active Zone by Zampighi, Guido A, Fain, Nick, Zampighi, Lorenzo M, Cantele, Francesca, Lanzavecchia, Salvatore, Wright, Ernest M

“…In this study, we tested the hypothesis that the structure of the active zone of chemical synapses has remained uncertain because of limitations of…”
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Micro-domains of AQP0 in Lens Equatorial Fibers by Zampighi, Guido A., Eskandari, Sepehr, Hall, James E., Zampighi, Lorenzo, Kreman, Michael

“…To understand why the water channel aquaporin-0 (AQP0) replaces aquaporin-1(AQP1) during lens development, we studied its spatial arrangement and interactions…”
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Regulation of Na+/glucose cotransporters by Wright, E M, Hirsch, J R, Loo, D D, Zampighi, G A

“…Na+/glucose cotransporters (SGLTs) are expressed in the small intestine and the proximal renal tubule, where they play a central role in the absorption of…”
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Number of Subunits Comprising the Epithelial Sodium Channel by Eskandari, Sepehr, Snyder, Peter M., Kreman, Michael, Zampighi, Guido A., Welsh, Michael J., Wright, Ernest M.

“…The human epithelial sodium channel (hENaC) is a hetero-oligomeric complex composed of three subunits, α, β, and γ. Understanding the structure and function of…”
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Protein Kinase C-γ Activation in the Early Streptozotocin Diabetic Rat Lens by Lin, Dingbo, Harris, Richie, Stutzman, Rachael, Zampighi, Guido A., Davidson, Harriett, Takemoto, Dolores J.

“…Purpose: The purpose of this study is to demonstrate the early activation of the protein kinase C-γ (PKC-γ) pathway in the streptozotocin (STZ)-induced…”
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Nerve Growth Factor Signals via Preexisting TrkA Receptor Oligomers by Mischel, Paul S., Umbach, Joy A., Eskandari, Sepehr, Smith, Shane G., Gundersen, Cameron B., Zampighi, Guido A.

“…Nerve growth factor (NGF) promotes neuronal survival and differentiation by activating TrkA receptors. Similar to other receptor tyrosine kinases,…”
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Coupled Sodium/Glucose Cotransport by SGLT1 Requires a Negative Charge at Position 454 by Díez-Sampedro, Ana, Loo, Donald D. F, Wright, Ernest M, Zampighi, Guido A, Hirayama, Bruce A

“…Na+/glucose cotransport by SGLT1 is a tightly coupled process that is driven by the Na+ electrochemical gradient across the plasma membrane. We have previously…”
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Structure of Functional Single AQP0 Channels in Phospholipid Membranes by Zampighi, Guido A, Kreman, Michael, Lanzavecchia, Salvatore, Turk, Eric, Eskandari, Sepehr, Zampighi, Lorenzo, Wright, Ernest M

“…Aquaporin-0 (AQP0) is the most prevalent intrinsic protein in the plasma membrane of lens fiber cells where it functions as a water selective channel and also…”
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Five Transmembrane Helices Form the Sugar Pathway through the Na+/Glucose Cotransporter by Panayotova-Heiermann, Mariana, Eskandari, Sepehr, Turk, Eric, Zampighi, Guido A., Wright, Ernest M.

“…To test the hypothesis that the C-terminal half of the Na+/glucose cotransporter (SGLT1) contains the sugar permeation pathway, a cDNA construct (C5) coding…”
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Cysteine string proteins : a potential link between synaptic vesicles and presynaptic Ca2+ channels by MASTROGIACOMO, A, PARSONS, S. M, ZAMPIGHI, G. A, JENDEN, D. J, UMBACH, J. A, GUNDERSEN, C. B

“…Presynaptic calcium channels are key regulators of neurotransmitter release. Oocyte expression studies suggest that cysteine string proteins are essential…”
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Synapses between Interneurons in the Rat Cerebral Cortex at 2NM Resolution and in Three-Dimensions by Zampighi, Guido A., Vergara, Julio

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The Three-Dimensional Distribution of [alpha]A-Crystalline in Rat Lenses and Its Possible Relation to Transparency by Zampighi, Guido A, Zampighi, Lorenzo, Lanzavecchia, Salvatore

“…Lens transparency depends on the accumulation of massive quantities (600-800 mg/ml) of twelve primary crystallines and two truncated crystallines in highly…”
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Conical Tomography: A Simple Method to Study Proteins in Cells at High Resolution by Zampighi, Guido A., Lanzavecchia, Salvatore, Zampighi, Lorenzo

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Conical Tomography of Ribbon Synapses of Light and Dark-Adapted Rod and Cones Photoreceptors by Zampighi, Guido A., Schietroma, Cataldo, Zampighi, Lorezo M., Brecha, Nicholas C.

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