Search Results - "Zamorano, Natalia"

ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities by Zamorano Cuervo, Natalia, Grandvaux, Nathalie

“…Pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus 19 disease (COVID-19) which presents a large spectrum of…”
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Redox proteomics and structural analyses provide insightful implications for additional non-catalytic thiol-disulfide motifs in PDIs by Cuervo, Natalia Zamorano, Grandvaux, Nathalie

“…Protein disulfide isomerases (PDIs) catalyze redox reactions that reduce, oxidize, or isomerize disulfide bonds and act as chaperones of proteins as they fold…”
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Pinpointing cysteine oxidation sites by high-resolution proteomics reveals a mechanism of redox-dependent inhibition of human STING by Zamorano Cuervo, Natalia, Fortin, Audray, Caron, Elise, Chartier, Stéfany, Grandvaux, Nathalie

“…Protein function is regulated by posttranslational modifications (PTMs), among which reversible oxidation of cysteine residues has emerged as a key regulatory…”
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DUOX2 regulates secreted factors in virus‐infected respiratory epithelial cells that contribute to neutrophil attraction and activation by Kasumba, Dacquin M., Huot, Sandrine, Caron, Elise, Fortin, Audray, Laflamme, Cynthia, Zamorano Cuervo, Natalia, Lamontagne, Felix, Pouliot, Marc, Grandvaux, Nathalie

“…The first line of defense against respiratory viruses relies on the antiviral and proinflammatory cytokine response initiated in infected respiratory…”
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Virus Infection Triggers MAVS Polymers of Distinct Molecular Weight by Zamorano Cuervo, Natalia, Osseman, Quentin, Grandvaux, Nathalie

“…The mitochondrial antiviral signaling (MAVS) adaptor protein is a central signaling hub required for cells to mount an antiviral response following virus…”
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Redox signaling in cell fate: Beyond damage by Lamontagne, Felix, Paz-Trejo, Cynthia, Zamorano Cuervo, Natalia, Grandvaux, Nathalie

“…This review explores the nuanced role of reactive oxygen species (ROS) in cell fate, challenging the traditional view that equates ROS with cellular damage…”
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Respiratory Syncytial Virus and Cellular Stress Responses: Impact on Replication and Physiopathology by Cervantes-Ortiz, Sandra L, Zamorano Cuervo, Natalia, Grandvaux, Nathalie

“…Human respiratory syncytial virus (RSV), a member of the Paramyxoviridae family, is a major cause of severe acute lower respiratory tract infection in infants,…”
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Clinical Evaluation of In-House-Produced 3D-Printed Nasopharyngeal Swabs for COVID-19 Testing by Grandjean Lapierre, Simon, Bedwani, Stéphane, DeBlois, François, Fortin, Audray, Zamorano Cuervo, Natalia, Zerouali, Karim, Caron, Elise, Morency-Potvin, Philippe, Gagnon, Simon, Nguissan, Nakome, Arlotto, Pascale, Hardy, Isabelle, Boutin, Catherine-Audrey, Tremblay, Cécile, Coutlée, François, de Guise, Jacques, Grandvaux, Nathalie

“…3D-printed alternatives to standard flocked swabs were rapidly developed to provide a response to the unprecedented and sudden need for an exponentially…”
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Detection of IKKε by immunohistochemistry in primary breast cancer: association with EGFR expression and absence of lymph node metastasis by Williams, Virginie, Grosset, Andrée-Anne, Zamorano Cuervo, Natalia, St-Pierre, Yves, Sylvestre, Marie-Pierre, Gaboury, Louis, Grandvaux, Nathalie

“…IKKε is an oncogenic kinase that was found amplified and overexpressed in a substantial percentage of human breast cancer cell lines and primary tumors using…”
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Undetectable histone O-GlcNAcylation in mammalian cells by Gagnon, Jessica, Daou, Salima, Zamorano, Natalia, Iannantuono, Nicholas V G, Hammond-Martel, Ian, Mashtalir, Nazar, Bonneil, Eric, Wurtele, Hugo, Thibault, Pierre, Affar, El Bachir

“…O-GlcNAcylation is a posttranslational modification catalyzed by the O-Linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) and reversed by O-GlcNAcase…”
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A potent nuclear export mechanism imposes USP16 cytoplasmic localization during interphase by Sen Nkwe, Nadine, Daou, Salima, Uriarte, Maxime, Gagnon, Jessica, Iannantuono, Nicholas Victor, Barbour, Haithem, Yu, Helen, Masclef, Louis, Fernández, Erlinda, Zamorano Cuervo, Natalia, Mashtalir, Nazar, Binan, Loïc, Sergeev, Mikhail, Bélanger, François, Drobetsky, Elliot, Milot, Eric, Wurtele, Hugo, Costantino, Santiago, Affar, El Bachir

“…USP16 (also known as UBP-M) has emerged as a histone H2AK119 deubiquitylase (DUB) implicated in the regulation of chromatin-associated processes and cell cycle…”
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Defective Influenza A Virus RNA Products Mediate MAVS-Dependent Upregulation of Human Leukocyte Antigen Class I Proteins by Rahim, Mir Munir A, Parsons, Brendon D, Price, Emma L, Slaine, Patrick D, Chilvers, Becca L, Seaton, Gregory S, Wight, Andrew, Medina-Luna, Daniel, Dey, Sayanti, Grandy, Shannen L, Anderson, Lauryn E, Zamorano Cuervo, Natalia, Grandvaux, Nathalie, Gaglia, Marta M, Kelvin, Alyson A, Khaperskyy, Denys A, McCormick, Craig, Makrigiannis, Andrew P

“…Influenza A virus (IAV) increases the presentation of class I human leukocyte antigen (HLA) proteins that limit antiviral responses mediated by natural killer…”
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Dynamic Regulation of MAVS Protein Function via Reversible Oxidation at Cys79 in Response to Oxidant Stimuli by Cuervo, Natalia Zamorano, Fortin, Audray, Arroyo, Alejandro Vallejo, Dehbidi, Layla, Caron, Elise, Grandvaux, Nathalie

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Inhibition of the STING-mediated Interferon Response by Novel Oxidative Posttranslational Modification by Zamorano, Natalia, Fortin, Audray, Caron, Elise, Chartier, Stéfany, Grandvaux, Nathalie

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Redox regulation of IFNg-mediated gene expression by Paz-Trejo, Cynthia, Fortin, Audray, Harrison, Alex, Caron, Elise, Cuervo, Natalia Zamorano, Grajales, Zayd, Chartier, Stéfany, Grandvaux, Nathalie

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Reversible thiol oxidation of the MAVS signaling adaptor: a novel regulatory mechanism of the antiviral response by Dufresne, Stéphanie, Cuervo, Natalia Zamorano, Caron, Elise, Fortin, Audray, Fakhfakh, Nesrine, Muthuraman, Srinivash, Grandvaux, Nathalie

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DUOX2 regulates secreted factors in virus-infected respiratory epithelial cells that contribute to neutrophil attraction and activation by Lamontagne, Felix, Kasumba, Dacquin M., Huot, Sandrine, Caron, Elise, Fortin, Audray, Laflamme, Cynthia, Cuervo, Natalia Zamorano, Pouliot, Marc, Grandvaux, Nathalie

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Enrichment of oxidised peptides of oxidised allows identification of oxidized cysteine residues in signaling proteins in vivo by Zamorano, Natalia, Grandvaux, Nathalie, Fortin, Audray, Chartier, Stéfany

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P-269 - Identification of oxidized cysteine residues in signaling proteins in vivo by Natalia, Zamorano, Audray, Fortin, Stéfany, Chartier, Nathalie, Grandvaux

“…Detection of oxidative post-translational modifications (ox-PTMs) of Cys residues in mammalian signaling proteins in vivo is one of the current challenges in…”
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Identification of oxidized cysteine residues in signaling proteins in vivo by Natalia, Zamorano, Audray, Fortin, Stéfany, Chartier, Nathalie, Grandvaux

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