Search Results - "Zambito, Giorgia"

Correction: Monitoring Immune Cell Function Through Optical Imaging: a Review Highlighting Transgenic Mouse Models by Chawda, Chintan, McMorrow, Roisin, Gaspar, Natasa, Zambito, Giorgia, Mezzanotte, Laura

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Monitoring Immune Cell Function Through Optical Imaging: a Review Highlighting Transgenic Mouse Models by Chawda, Chintan, McMorrow, Roisin, Gaspar, Natasa, Zambito, Giorgia, Mezzanotte, Laura

“…Transgenic mouse models have facilitated research of human diseases and validation of therapeutic approaches. Inclusion of optical reporter genes (fluorescent…”
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Evaluation of NanoLuc substrates for bioluminescence imaging of transferred cells in mice by Gaspar, Natasa, Walker, Joel R., Zambito, Giorgia, Marella-Panth, Kranthi, Lowik, Clemens, Kirkland, Thomas A., Mezzanotte, Laura

“…NanoLuc luciferase recently gained popularity due to its small size and superior bioluminescence performance. For in vivo imaging applications, NanoLuc has…”
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Active Nano-targeting of Macrophages by Gaspar, Natasa, Zambito, Giorgia, Löwik, Clemens M W G, Mezzanotte, Laura

“…Macrophages play a role in almost every disease such as cancer, infections, injuries, metabolic and inflammatory diseases and are becoming an attractive…”
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Near-infrared bioluminescence imaging of two cell populations in living mice by Zambito, Giorgia, Mezzanotte, Laura

“…Multicolor bioluminescence imaging using near-infrared emitting luciferases is an attractive application to detect two cell populations within one animal…”
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Evaluating Brightness and Spectral Properties of Click Beetle and Firefly Luciferases Using Luciferin Analogues: Identification of Preferred Pairings of Luciferase and Substrate for In Vivo Bioluminescence Imaging by Zambito, Giorgia, Gaspar, Natasa, Ridwan, Yanto, Hall, Mary P., Shi, Ce, Kirkland, Thomas A., Encell, Lance P., Löwik, Clemens, Mezzanotte, Laura

“…Purpose Currently, a variety of red and green beetle luciferase variants are available for bioluminescence imaging (BLI). In addition, new luciferin analogues…”
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Near-Infrared Bioluminescence Imaging of Macrophage Sensors for Cancer Detection In Vivo by Zambito, Giorgia, Mishra, Gunja, Schliehe, Christopher, Mezzanotte, Laura

“…Melanoma is an aggressive type of skin cancer with a poor prognosis after it gets metastasized. The early detection of malignant melanoma is critical for…”
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A Dual-Color Bioluminescence Reporter Mouse for Simultaneous in vivo Imaging of T Cell Localization and Function by Kleinovink, Jan Willem, Mezzanotte, Laura, Zambito, Giorgia, Fransen, Marieke F, Cruz, Luis J, Verbeek, J Sjef, Chan, Alan, Ossendorp, Ferry, Löwik, Clemens

“…Non-invasive imaging technologies to visualize the location and functionality of T cells are of great value in immunology. Here, we describe the design and…”
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Whole-body bioluminescence imaging of T-cell response in PDAC models by McMorrow, Roisin, Zambito, Giorgia, Nigg, Alex, Lila, Karishma, van den Bosch, Thierry P P, Lowik, Clemens W G M, Mezzanotte, Laura

“…The location of T-cells during tumor progression and treatment provides crucial information in predicting the response . Here, we investigated, using our…”
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NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice-A Novel in Vivo Imaging Platform by Gaspar, Natasa, Zambito, Giorgia, Dautzenberg, Iris J C, Cramer, Steve J, Hoeben, Rob C, Lowik, Clemens, Walker, Joel R, Kirkland, Thomas A, Smith, Thomas P, van Weerden, Wytske M, de Vrij, Jeroen, Mezzanotte, Laura

“…Reporter genes are used to visualize intracellular biological phenomena, including viral infection. Here we demonstrate bioluminescent imaging of viral…”
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Fluorinated PLGA-PEG-Mannose Nanoparticles for Tumor-Associated Macrophage Detection by Optical Imaging and MRI by Zambito, Giorgia, Deng, Siyuan, Haeck, Joost, Gaspar, Natasa, Himmelreich, Uwe, Censi, Roberta, Löwik, Clemens, Di Martino, Piera, Mezzanotte, Laura

“…Tumor-associated macrophages (TAMs) promote cancer growth and metastasis, but their role in tumor development needs to be fully understood due to the dynamic…”
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Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy by Deng, Siyuan, Iscaro, Alessandra, Zambito, Giorgia, Mijiti, Yimin, Minicucci, Marco, Essand, Magnus, Lowik, Clemens, Muthana, Munitta, Censi, Roberta, Mezzanotte, Laura, Di Martino, Piera

“…Oncolytic viruses (OVs) are emerging as promising and potential anti-cancer therapeutic agents, not only able to kill cancer cells directly by selective…”
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Red-shifted click beetle luciferase mutant expands the multicolor bioluminescent palette for deep tissue imaging by Zambito, Giorgia, Hall, Mary P., Wood, Monika G., Gaspar, Natasa, Ridwan, Yanto, Stellari, Fabio F., Shi, Ce, Kirkland, Thomas A., Encell, Lance P., Löwik, Clemens, Mezzanotte, Laura

“…For in vivo multicolor bioluminescence applications, red and near-infrared signals are desirable over shorter wavelength signals because they are not as…”
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Dually Cross-Linked Core-Shell Structure Nanohydrogel with Redox-Responsive Degradability for Intracellular Delivery by Deng, Siyuan, Gigliobianco, Maria Rosa, Mijit, Emin, Minicucci, Marco, Cortese, Manuela, Campisi, Barbara, Voinovich, Dario, Battistelli, Michela, Salucci, Sara, Gobbi, Pietro, Lupidi, Giulio, Zambito, Giorgia, Mezzanotte, Laura, Censi, Roberta, Di Martino, Piera

“…A redox-responsive nanocarrier is a promising strategy for the intracellular drug release because it protects the payload, prevents its undesirable leakage…”
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Emerging tools for bioluminescence imaging by Zambito, Giorgia, Chawda, Chintan, Mezzanotte, Laura

“…Bioluminescence (BL) relies on the enzymatic reaction between luciferase, a substrate conventionally named luciferin, and various cofactors. BL imaging has…”
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Bioluminescence imaging on-chip platforms for non-invasive high-content bioimaging by Araújo-Gomes, Nuno, Zambito, Giorgia, Johnbosco, Castro, Calejo, Isabel, Leijten, Jeroen, Löwik, Clemens, Karperien, Marcel, Mezzanotte, Laura, Teixeira, Liliana Moreira

“…Incorporating non-invasive biosensing features in organ-on-chip models is of paramount importance for a wider implementation of these advanced in vitro…”
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Theranostic Design of Angiopep-2 Conjugated Hyaluronic Acid Nanoparticles (Thera-ANG-cHANPs) for Dual Targeting and Boosted Imaging of Glioma Cells by Costagliola di Polidoro, Angela, Zambito, Giorgia, Haeck, Joost, Mezzanotte, Laura, Lamfers, Martine, Netti, Paolo Antonio, Torino, Enza

“…Glioblastoma multiforme (GBM) has a mean survival of only 15 months. Tumour heterogeneity and blood-brain barrier (BBB) mainly hinder the transport of active…”
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