Search Results - "Zamarron, Brian"

Dual roles of immune cells and their factors in cancer development and progression by Zamarron, Brian F, Chen, WanJun

“…Traditional wisdom holds that intact immune responses, such as immune surveillance or immunoediting, are required for preventing and inhibiting tumor…”
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Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice by Zamarron, Brian F, Mergian, Taleen A, Cho, Kae Won, Martinez-Santibanez, Gabriel, Luan, Danny, Singer, Kanakadurga, DelProposto, Jennifer L, Geletka, Lynn M, Muir, Lindsey A, Lumeng, Carey N

“…Obesity causes dramatic proinflammatory changes in the adipose tissue immune environment, but relatively little is known regarding how this inflammation…”
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Adipose Tissue Dendritic Cells Are Independent Contributors to Obesity-Induced Inflammation and Insulin Resistance by Cho, Kae Won, Zamarron, Brian F, Muir, Lindsey A, Singer, Kanakadurga, Porsche, Cara E, DelProposto, Jennifer B, Geletka, Lynn, Meyer, Kevin A, O'Rourke, Robert W, Lumeng, Carey N

“…Dynamic changes of adipose tissue leukocytes, including adipose tissue macrophage (ATM) and adipose tissue dendritic cells (ATDCs), contribute to…”
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Differences in Hematopoietic Stem Cells Contribute to Sexually Dimorphic Inflammatory Responses to High Fat Diet-induced Obesity by Singer, Kanakadurga, Maley, Nidhi, Mergian, Taleen, DelProposto, Jennifer, Cho, Kae Won, Zamarron, Brian F., Martinez-Santibanez, Gabriel, Geletka, Lynn, Muir, Lindsey, Wachowiak, Phillip, Demirjian, Chaghig, Lumeng, Carey N.

“…Women of reproductive age are protected from metabolic disease relative to postmenopausal women and men. Most preclinical rodent studies are skewed toward the…”
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Adipose tissue fibrosis, hypertrophy, and hyperplasia: Correlations with diabetes in human obesity by Muir, Lindsey A., Neeley, Christopher K., Meyer, Kevin A., Baker, Nicki A., Brosius, Alice M., Washabaugh, Alexandra R., Varban, Oliver A., Finks, Jonathan F., Zamarron, Brian F., Flesher, Carmen G., Chang, Joshua S., DelProposto, Jennifer B., Geletka, Lynn, Martinez‐Santibanez, Gabriel, Kaciroti, Niko, Lumeng, Carey N., O'Rourke, Robert W.

“…Objective The relationship between adipose tissue fibrosis, adipocyte hypertrophy, and preadipocyte hyperplasia in the context of obesity and the correlation…”
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Changes in Skeletal Integrity and Marrow Adiposity during High-Fat Diet and after Weight Loss by Scheller, Erica L, Khoury, Basma, Moller, Kayla L, Wee, Natalie K Y, Khandaker, Shaima, Kozloff, Kenneth M, Abrishami, Simin H, Zamarron, Brian F, Singer, Kanakadurga

“…The prevalence of obesity has continued to rise over the past three decades leading to significant increases in obesity-related medical care costs from…”
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Control of the development of CD8αα + intestinal intraepithelial lymphocytes by TGF-β by Chen, WanJun, Konkel, Joanne E, Maruyama, Takashi, Carpenter, Andrea C, Xiong, Yumei, Zamarron, Brian F, Hall, Bradford E, Kulkarni, Ashok B, Zhang, Pin, Bosselut, Remy

“…The molecular mechanisms that direct the development of intestinal intraepithelial lymphocytes (IELs) remain unclear. Chen and co-workers demonstrate a role…”
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Adipose tissue dendritic cell signals are required to maintain T cell homeostasis and obesity-induced expansion by Porsche, Cara E., Delproposto, Jennifer B., Patrick, Elise, Zamarron, Brian F., Lumeng, Carey N.

“…Adipose tissue derived chronic inflammation is a critical component of obesity induced type II diabetes. Major histocompatibility complex II (MHCII) mediated T…”
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Frontline Science: Rapid adipose tissue expansion triggers unique proliferation and lipid accumulation profiles in adipose tissue macrophages by Muir, Lindsey A., Kiridena, Samadhi, Griffin, Cameron, DelProposto, Jennifer B., Geletka, Lynn, Martinez‐Santibañez, Gabriel, Zamarron, Brian F., Lucas, Hannah, Singer, Kanakadurga, O’ Rourke, Robert W., Lumeng, Carey N.

“…Obesity‐related changes in adipose tissue leukocytes, in particular adipose tissue macrophages (ATMs) and dendritic cells (ATDCs), are implicated in metabolic…”
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A subcutaneous adipose tissue–liver signalling axis controls hepatic gluconeogenesis by Reilly, Shannon M., Ahmadian, Maryam, Zamarron, Brian F., Chang, Louise, Uhm, Maeran, Poirier, BreAnne, Peng, Xiaoling, Krause, Danielle M., Korytnaya, Evgenia, Neidert, Adam, Liddle, Christopher, Yu, Ruth T., Lumeng, Carey N., Oral, Elif A., Downes, Michael, Evans, Ronald M., Saltiel, Alan R.

“…The search for effective treatments for obesity and its comorbidities is of prime importance. We previously identified IKK-ε and TBK1 as promising therapeutic…”
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An MHC II-Dependent Activation Loop between Adipose Tissue Macrophages and CD4+ T Cells Controls Obesity-Induced Inflammation by Cho, Kae Won, Morris, David L., DelProposto, Jennifer L., Geletka, Lynn, Zamarron, Brian, Martinez-Santibanez, Gabriel, Meyer, Kevin A., Singer, Kanakadurga, O’Rourke, Robert W., Lumeng, Carey N.

“…An adaptive immune response triggered by obesity is characterized by the activation of adipose tissue CD4+ T cells by unclear mechanisms. We have examined…”
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Weight Regain in Formerly Obese Mice Hastens Development of Hepatic Steatosis Due to Impaired Adipose Tissue Function by Zamarron, Brian F., Porsche, Cara E., Luan, Danny, Lucas, Hannah R., Mergian, Taleen A., Martinez‐Santibanez, Gabriel, Cho, Kae Won, DelProposto, Jennifer L., Geletka, Lynn M., Muir, Lindsey A., Singer, Kanakadurga, Lumeng, Carey N.

“…Objective Weight regain after weight loss is common, and there is evidence to suggest negative effects on health because of weight cycling. This study sought…”
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Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3 by Maruyama, Takashi, Li, Jun, Vaque, Jose P, Konkel, Joanne E, Wang, Weifeng, Zhang, Baojun, Zhang, Pin, Zamarron, Brian F, Yu, Dongyang, Wu, Yuntao, Zhuang, Yuan, Gutkind, J Silvio, Chen, WanJun

“…The molecular mechanisms that direct transcription of the gene encoding the transcription factor Foxp3 in CD4(+) T cells remain ill-defined. We show here that…”
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The molecular mechanisms of Foxp3 gene regulation by Maruyama, Takashi, Konkel, Joanne E, Zamarron, Brian F, Chen, WanJun

“…Highlights • Foxp3 gene conserved regions. • TGF-β and Foxp3 gene expression. • Repressors of Foxp3 gene transcription…”
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Initial Experience Integrating a Hands-On Innovation Curriculum Into a Radiology Residency Program and Department by Succi, Marc D., Zamarron, Brian F., Fintelmann, Florian J., Andriole, Katherine P., Ottensmeyer, Mark P., Whitehead, David C., Harris, Gordon J., McLoud, Theresa C., Brink, James A., Gee, Michael S., Uppot, Raul N.

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Weight loss independent changes in adipose tissue macrophage and T cell populations after sleeve gastrectomy in mice by Frikke-Schmidt, Henriette, Zamarron, Brian F, O'Rourke, Robert W, Sandoval, Darleen A, Lumeng, Carey N, Seeley, Randy J

“…Abstract Objective In addition to adipocytes, adipose tissue contains large numbers of immune cells. A wide range of evidence links the activity of these cells…”
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PARP-1 controls immunosuppressive function of regulatory T cells by destabilizing Foxp3 by Zhang, Pin, Maruyama, Takashi, Konkel, Joanne E, Abbatiello, Brittany, Zamarron, Brian, Wang, Zhao-qi, Chen, Wanjun

“…Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme and transcription factor that is involved in inflammatory response, but its role in T cell response…”
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Inflammatory responses to dietary and surgical weight loss in male and female mice by Griffin, Cameron, Hutch, Chelsea R, Abrishami, Simin, Stelmak, Daria, Eter, Leila, Li, Ziru, Chang, Eric, Agarwal, Devyani, Zamarron, Brian, Varghese, Mita, Subbaiah, Perla, MacDougald, Ormond A, Sandoval, Darleen A, Singer, Kanakadurga

“…Weight loss by surgery or lifestyle changes is strongly recommended for obese individuals to improve metabolic health, but the underlying impairments that…”
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Impact of weight loss on obese adipose tissue immune cell function (CAM1P.154) by Zamarron, Brian, Mergian, Taleen, Martinez-Santibanez, Gabriel, Lumeng, Carey

“…Obesity induces inflammation in adipose tissue involving the recruitment and activation of macrophages, CD8+ and CD4+ T cells. These cells play a critical role…”
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Persistence of inflammatory adipose tissue immune cells despite weight loss in obese mice by Zamarron, Brian F, Mergian, Taleen, Martinez-Santibanez, Gabriel, Luan, Danny, Lumeng, Carey N

“…Obesity causes dramatic changes to the adipose tissue immune environment including the recruitment and activation of macrophages. The inflammatory polarization…”
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