Search Results - "Zalucki, Oressia H"
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Trapping of Syntaxin1a in Presynaptic Nanoclusters by a Clinically Relevant General Anesthetic
Published in Cell reports (Cambridge) (09-01-2018)“…Propofol is the most commonly used general anesthetic in humans. Our understanding of its mechanism of action has focused on its capacity to potentiate…”
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Syntaxin1A Neomorphic Mutations Promote Rapid Recovery from Isoflurane Anesthesia in Drosophila melanogaster
Published in Anesthesiology (Philadelphia) (01-09-2019)“…WHAT WE ALREADY KNOW ABOUT THIS TOPICSyntaxin1A is a presynaptic molecule that plays a key role in vesicular neurotransmitter releaseMutations of syntaxin1A…”
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Syntaxin1A-mediated Resistance and Hypersensitivity to Isoflurane in Drosophila melanogaster
Published in Anesthesiology (Philadelphia) (01-05-2015)“…Recent evidence suggests that general anesthetics activate endogenous sleep pathways, yet this mechanism cannot explain the entirety of general anesthesia…”
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Local Versus Global Effects of Isoflurane Anesthesia on Visual Processing in the Fly Brain
Published in eNeuro (01-07-2016)“…What characteristics of neural activity distinguish the awake and anesthetized brain? Drugs such as isoflurane abolish behavioral responsiveness in all…”
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Proportional Downscaling of Glutamatergic Release Sites by the General Anesthetic Propofol at Drosophila Motor Nerve Terminals
Published in eNeuro (01-01-2020)“…Propofol is the most common general anesthetic used for surgery in humans, yet its complete mechanism of action remains elusive. In addition to potentiating…”
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