Search Results - "Zaloga Jan"

Magnetic nanoparticle-based drug delivery for cancer therapy by Tietze, Rainer, Zaloga, Jan, Unterweger, Harald, Lyer, Stefan, Friedrich, Ralf P., Janko, Christina, Pöttler, Marina, Dürr, Stephan, Alexiou, Christoph

“…Nanoparticles have belonged to various fields of biomedical research for quite some time. A promising site-directed application in the field of nanomedicine is…”
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Facile preparation of multifunctional superparamagnetic PHBV microspheres containing SPIONs for biomedical applications by Li, Wei, Jan Zaloga, Ding, Yaping, Liu, Yufang, Janko, Christina, Pischetsrieder, Monika, Alexiou, Christoph, Boccaccini, Aldo R.

“…The promising potential of magnetic polymer microspheres in various biomedical applications has been frequently reported. However, the surface hydrophilicity…”
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Selection of potential iron oxide nanoparticles for breast cancer treatment based on in vitro cytotoxicity and cellular uptake by Poller, Johanna M, Zaloga, Jan, Schreiber, Eveline, Unterweger, Harald, Janko, Christina, Radon, Patricia, Eberbeck, Dietmar, Trahms, Lutz, Alexiou, Christoph, Friedrich, Ralf P

“…Superparamagnetic iron oxide nanoparticles (SPIONs) are promising tools for the treatment of different diseases. Their magnetic properties enable therapies…”
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Surface Modification of SPIONs in PHBV Microspheres for Biomedical Applications by Idris, Maizlinda I., Zaloga, Jan, Detsch, Rainer, Roether, Judith A., Unterweger, Harald, Alexiou, Christoph, Boccaccini, Aldo R.

“…Surface modification of superparamagnetic iron oxide nanoparticles (SPIONs) has been introduced with lauric acid and oleic acid via co-precipitation and…”
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Different storage conditions influence biocompatibility and physicochemical properties of iron oxide nanoparticles by Zaloga, Jan, Janko, Christina, Agarwal, Rohit, Nowak, Johannes, Müller, Robert, Boccaccini, Aldo R, Lee, Geoffrey, Odenbach, Stefan, Lyer, Stefan, Alexiou, Christoph

“…Superparamagnetic iron oxide nanoparticles (SPIONs) have attracted increasing attention in many biomedical fields. In magnetic drug targeting SPIONs are…”
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Magnetic nanoparticles for cancer therapy by Dürr Stephan, Janko Christina, Lyer Stefan, Tripal Philipp, Schwarz Marc, Zaloga Jan, Tietze Rainer, Alexiou Christoph

“…Cancer is one of the biggest challenges facing the medical research in our time. The goals are to improve not only the therapeutic outcome, even in the cases…”
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Treatment Efficiency of Free and Nanoparticle-Loaded Mitoxantrone for Magnetic Drug Targeting in Multicellular Tumor Spheroids by Hornung, Annkathrin, Poettler, Marina, Friedrich, Ralf P, Zaloga, Jan, Unterweger, Harald, Lyer, Stefan, Nowak, Johannes, Odenbach, Stefan, Alexiou, Christoph, Janko, Christina

“…Major problems of cancer treatment using systemic chemotherapy are severe side effects. Magnetic drug targeting (MDT) employing superparamagnetic iron oxide…”
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Tangential Flow Ultrafiltration Allows Purification and Concentration of Lauric Acid-/Albumin-Coated Particles for Improved Magnetic Treatment by Zaloga, Jan, Stapf, Marcus, Nowak, Johannes, Pöttler, Marina, Friedrich, Ralf P, Tietze, Rainer, Lyer, Stefan, Lee, Geoffrey, Odenbach, Stefan, Hilger, Ingrid, Alexiou, Christoph

“…Superparamagnetic iron oxide nanoparticles (SPIONs) are frequently used for drug targeting, hyperthermia and other biomedical purposes. Recently, we have…”
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Genotoxicity of Superparamagnetic Iron Oxide Nanoparticles in Granulosa Cells by Pöttler, Marina, Staicu, Andreas, Zaloga, Jan, Unterweger, Harald, Weigel, Bianca, Schreiber, Eveline, Hofmann, Simone, Wiest, Irmi, Jeschke, Udo, Alexiou, Christoph, Janko, Christina

“…Nanoparticles that are aimed at targeting cancer cells, but sparing healthy tissue provide an attractive platform of implementation for hyperthermia or as…”
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Strategies to optimize the biocompatibility of iron oxide nanoparticles – “SPIONs safe by design” by Janko, Christina, Zaloga, Jan, Pöttler, Marina, Dürr, Stephan, Eberbeck, Dietmar, Tietze, Rainer, Lyer, Stefan, Alexiou, Christoph

“…Various nanoparticle systems have been developed for medical applications in recent years. For constant improvement of efficacy and safety of nanoparticles, a…”
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Studies on the adsorption and desorption of mitoxantrone to lauric acid/albumin coated iron oxide nanoparticles by Zaloga, Jan, Feoktystov, Artem, Garamus, Vasil M., Karawacka, Weronika, Ioffe, Alexander, Brückel, Thomas, Tietze, Rainer, Alexiou, Christoph, Lyer, Stefan

“…[Display omitted] •Mitoxantrone has high affinity to albumin coated iron oxide nanoparticles.•Albumin coated particles show sustainable release of…”
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Drug delivery to atherosclerotic plaques using superparamagnetic iron oxide nanoparticles by Matuszak, Jasmin, Lutz, Barbara, Sekita, Aleksander, Zaloga, Jan, Alexiou, Christoph, Lyer, Stefan, Cicha, Iwona

“…Magnetic drug targeting utilizes superparamagnetic iron oxide nanoparticles (SPIONs) to accumulate drugs in specified vasculature regions. We produced SPIONs…”
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Endothelial biocompatibility and accumulation of SPION under flow conditions by Matuszak, Jasmin, Zaloga, Jan, Friedrich, Ralf P., Lyer, Stefan, Nowak, Johannes, Odenbach, Stefan, Alexiou, Christoph, Cicha, Iwona

“…Magnetic targeting is considered a promising method to accumulate the nanoparticles at the sites of atherosclerotic lesions, but little is known about the…”
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Pharmaceutical formulation of HSA hybrid coated iron oxide nanoparticles for magnetic drug targeting by Zaloga, Jan, Pöttler, Marina, Leitinger, Gerd, Friedrich, Ralf P., Almer, Gunter, Lyer, Stefan, Baum, Eva, Tietze, Rainer, Heimke-Brinck, Ralph, Mangge, Harald, Dörje, Frank, Lee, Geoffrey, Alexiou, Christoph

“…[Display omitted] In this work we present a new formulation of superparamagnetic iron oxide nanoparticles (SPIONs) for magnetic drug targeting. The particles…”
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Development and characterization of magnetic iron oxide nanoparticles with a cisplatin-bearing polymer coating for targeted drug delivery by Unterweger, Harald, Tietze, Rainer, Janko, Christina, Zaloga, Jan, Lyer, Stefan, Dürr, Stephan, Taccardi, Nicola, Goudouri, Ourania-Menti, Hoppe, Alexander, Eberbeck, Dietmar, Schubert, Dirk W, Boccaccini, Aldo R, Alexiou, Christoph

“…A highly selective and efficient cancer therapy can be achieved using magnetically directed superparamagnetic iron oxide nanoparticles (SPIONs) bearing a…”
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Flow cytometry for intracellular SPION quantification: specificity and sensitivity in comparison with spectroscopic methods by Friedrich, Ralf P, Janko, Christina, Poettler, Marina, Tripal, Philipp, Zaloga, Jan, Cicha, Iwona, Dürr, Stephan, Nowak, Johannes, Odenbach, Stefan, Slabu, Ioana, Liebl, Maik, Trahms, Lutz, Stapf, Marcus, Hilger, Ingrid, Lyer, Stefan, Alexiou, Christoph

“…Due to their special physicochemical properties, iron nanoparticles offer new promising possibilities for biomedical applications. For bench to bedside…”
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Toxicity of Mitoxantrone-loaded Superparamagnetic Iron Oxide Nanoparticles in a HT-29 Tumour Spheroid Model by Hornung, Annkathrin, Poettler, Marina, Friedrich, Ralf P, Weigel, Bianca, Duerr, Stephan, Zaloga, Jan, Cicha, Iwona, Alexiou, Christoph, Janko, Christina

“…Cancer research is commonly carried out in two-dimensional (2D) cell cultures, which poorly reflect in vivo settings where the growing tumours are exposed to…”
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Development of a lauric acid/albumin hybrid iron oxide nanoparticle system with improved biocompatibility by Zaloga, Jan, Janko, Christina, Nowak, Johannes, Matuszak, Jasmin, Knaup, Sabine, Eberbeck, Dietmar, Tietze, Rainer, Unterweger, Harald, Friedrich, Ralf P, Duerr, Stephan, Heimke-Brinck, Ralph, Baum, Eva, Cicha, Iwona, Dörje, Frank, Odenbach, Stefan, Lyer, Stefan, Lee, Geoffrey, Alexiou, Christoph

“…The promising potential of superparamagnetic iron oxide nanoparticles (SPIONs) in various nanomedical applications has been frequently reported. However,…”
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Nanomedical innovation: the SEON-concept for an improved cancer therapy with magnetic nanoparticles by Lyer, Stefan, Tietze, Rainer, Unterweger, Harald, Zaloga, Jan, Singh, Raminder, Matuszak, Jasmin, Poettler, Marina, Friedrich, Ralf P, Duerr, Stephan, Cicha, Iwona, Janko, Christina, Alexiou, Christoph

“…Nanomedicine offers tremendous opportunities for the development of novel therapeutic and diagnostic tools. During the last decades, extensive knowledge was…”
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Tissue Plasminogen Activator Binding to Superparamagnetic Iron Oxide Nanoparticle—Covalent Versus Adsorptive Approach by Friedrich, Ralf P, Zaloga, Jan, Schreiber, Eveline, Tóth, Ildikó Y, Tombácz, Etelka, Lyer, Stefan, Alexiou, Christoph

“…Functionalized superparamagnetic iron oxide nanoparticles are frequently used to develop vehicles for drug delivery, hyperthermia, and photodynamic therapy and…”
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