Search Results - "Zalloua, Pierre"
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Genomic ancestry of North Africans supports back-to-Africa migrations
Published in PLoS genetics (01-01-2012)“…North African populations are distinct from sub-Saharan Africans based on cultural, linguistic, and phenotypic attributes; however, the time and the extent of…”
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Plasma and urine metabolomic analyses in aortic valve stenosis reveal shared and biofluid-specific changes in metabolite levels
Published in PloS one (25-11-2020)“…Aortic valve stenosis (AVS) is a prevalent condition among the elderly population that eventually requires aortic valve replacement. The lack of reliable…”
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3
Deep phylogenetic analysis of haplogroup G1 provides estimates of SNP and STR mutation rates on the human Y-chromosome and reveals migrations of Iranic speakers
Published in PloS one (07-04-2015)“…Y-chromosomal haplogroup G1 is a minor component of the overall gene pool of South-West and Central Asia but reaches up to 80% frequency in some populations…”
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4
Whole-genome sequence analysis of a Pan African set of samples reveals archaic gene flow from an extinct basal population of modern humans into sub-Saharan populations
Published in Genome Biology (26-04-2019)“…Population demography and gene flow among African groups, as well as the putative archaic introgression of ancient hominins, have been poorly explored at the…”
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5
Lies, Gosh Darn Lies, and not enough good statistics: why epidemic model parameter estimation fails
Published in Scientific reports (11-01-2021)“…We sought to investigate whether epidemiological parameters that define epidemic models could be determined from the epidemic trajectory of infections,…”
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6
Anatolian genetic ancestry in North Lebanese populations
Published in Scientific reports (05-07-2024)“…Lebanon’s rich history as a cultural crossroad spanning millennia has significantly impacted the genetic composition of its population through successive waves…”
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People from Ibiza: an unexpected isolate in the Western Mediterranean
Published in European journal of human genetics : EJHG (01-06-2019)“…In this study, we seek to understand and to correlate the genetic patterns observed in the population of the island of Ibiza in the Western Mediterranean basin…”
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Recent Historical Migrations Have Shaped the Gene Pool of Arabs and Berbers in North Africa
Published in Molecular biology and evolution (01-02-2017)“…North Africa is characterized by its diverse cultural and linguistic groups and its genetic heterogeneity. Genomic data has shown an amalgam of components…”
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Chad Genetic Diversity Reveals an African History Marked by Multiple Holocene Eurasian Migrations
Published in American journal of human genetics (01-12-2016)“…Understanding human genetic diversity in Africa is important for interpreting the evolution of all humans, yet vast regions in Africa, such as Chad, remain…”
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10
Genetic evidence for an origin of the Armenians from Bronze Age mixing of multiple populations
Published in European journal of human genetics : EJHG (01-06-2016)“…The Armenians are a culturally isolated population who historically inhabited a region in the Near East bounded by the Mediterranean and Black seas and the…”
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Tracing the Route of Modern Humans out of Africa by Using 225 Human Genome Sequences from Ethiopians and Egyptians
Published in American journal of human genetics (04-06-2015)“…The predominantly African origin of all modern human populations is well established, but the route taken out of Africa is still unclear. Two alternative…”
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A European Mitochondrial Haplotype Identified in Ancient Phoenician Remains from Carthage, North Africa
Published in PloS one (25-05-2016)“…While Phoenician culture and trade networks had a significant impact on Western civilizations, we know little about the Phoenicians themselves. In 1994, a…”
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13
Coronary artery disease patients with rs7904519 (TCF7L2) are at a persistent risk of type 2 diabetes
Published in Diabetes research and clinical practice (01-01-2024)“…Type 2 diabetes (T2D) and coronary artery disease (CAD) often coexist and share genetic factors.This study aimed to investigate the common genetic factors…”
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14
PHACTR1 and APOC1 genetic variants are associated with multi-vessel coronary artery disease
Published in Lipids in health and disease (12-10-2024)“…Severe coronary artery disease (CAD) represents an advanced arterial narrowing, often associated with critical complications like myocardial infarction and…”
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Genome-wide diversity in the levant reveals recent structuring by culture
Published in PLoS genetics (01-02-2013)“…The Levant is a region in the Near East with an impressive record of continuous human existence and major cultural developments since the Paleolithic period…”
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Large scale association analysis identifies three susceptibility loci for coronary artery disease
Published in PloS one (27-12-2011)“…Genome wide association studies (GWAS) and their replications that have associated DNA variants with myocardial infarction (MI) and/or coronary artery disease…”
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17
Mutations and variants of ONECUT1 in diabetes
Published in Nature medicine (01-11-2021)“…Genes involved in distinct diabetes types suggest shared disease mechanisms. Here we show that One Cut Homeobox 1 ( ONECUT1 ) mutations cause monogenic…”
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Assessment of genetic and clinical factors in T2D susceptibility among patients with hypertension
Published in Acta diabetologica (01-10-2024)“…Aims Hypertension (HTN) and Type 2 Diabetes (T2D) often coexist, therefore understanding the relationship between both diseases is imperative to guide targeted…”
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Ancient DNA of Phoenician remains indicates discontinuity in the settlement history of Ibiza
Published in Scientific reports (04-12-2018)“…Ibiza was permanently settled around the 7 th century BCE by founders arriving from west Phoenicia. The founding population grew significantly and reached its…”
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Y-chromosome and mtDNA genetics reveal significant contrasts in affinities of modern Middle Eastern populations with European and African populations
Published in PloS one (30-01-2013)“…The Middle East was a funnel of human expansion out of Africa, a staging area for the Neolithic Agricultural Revolution, and the home to some of the earliest…”
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