Search Results - "Zalis, Mariano"
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Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation
Published in The Lancet global health (01-10-2017)“…Malaria was eliminated from southern and southeastern Brazil over 50 years ago. However, an increasing number of autochthonous episodes attributed to…”
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Simian malaria in the Brazilian Atlantic forest: first description of natural infection of capuchin monkeys (Cebinae subfamily) by Plasmodium simium
Published in Malaria journal (18-02-2015)“…In Brazil, two species of Plasmodium have been described infecting non-human primates, Plasmodium brasilianum and Plasmodium simium. These species are…”
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Cerebrospinal Fluid Immunoglobulins as Potential Biomarkers of Chikungunya Encephalitis
Published in Emerging infectious diseases (01-05-2018)“…Chikungunya virus causes fever and severe polyarthritis or arthralgia and is associated with neurologic manifestations that are sometimes challenging to…”
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Next-generation sequencing impact on cancer care: applications, challenges, and future directions
Published in Frontiers in genetics (09-07-2024)“…Fundamentally precision oncology illustrates the path in which molecular profiling of tumors can illuminate their biological behavior, diversity, and likely…”
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BK polyomavirus genotypes Ia and Ib1 exhibit different biological properties in renal transplant recipients
Published in Virus research (02-01-2018)“…•BKV Ia genotype exhibited higher viral loads in urine and mutations at VP1 region.•The few patients who developed BKV nephropathy were infected with genotype…”
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Evaluation of KRAS Concomitant Mutations in Advanced Lung Adenocarcinoma Patients
Published in Medicina (Kaunas, Lithuania) (29-09-2021)“…: One of the most frequently mutated oncogenes in cancer belongs to the Ras family of proto-oncogenes, which encode distinct key signaling events. RAS…”
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Review of the etiologies of viral meningitis and encephalitis in a dengue endemic region
Published in Journal of the neurological sciences (15-04-2011)“…Abstract Objectives To evaluate the etiology of viral meningitis and encephalitis in adults and adolescents living in areas affected by dengue. Methods Over…”
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Population genetics of GYPB and association study between GYPBS/s polymorphism and susceptibility to P. falciparum infection in the Brazilian Amazon
Published in PloS one (24-01-2011)“…Merozoites of Plasmodium falciparum invade through several pathways using different RBC receptors. Field isolates appear to use a greater variability of these…”
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Phylogenetic and structural analysis of merkel cell polyomavirus VP1 in Brazilian samples
Published in Virus research (02-08-2016)“…•The MCPyV South-American clade is heterogeneous.•Brazilian sequences were clustered in the Caucasian; African and South-American clades.•Some VP1 mutations…”
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EGFR Mutation Detection in Brazilian Patients With Non-Small-Cell Lung Cancer: Lessons From Real-World Data Scenario of Molecular Testing
Published in JCO global oncology (01-09-2023)“…There is a paucity of consistent data concerning genetic mutations in Brazilian patients with lung cancer. The aim of this study was to retrospectively analyze…”
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Antimalarial activity of phenazines from lapachol, β-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo
Published in Bioorganic & medicinal chemistry letters (08-03-2004)“…The antimalarial activity of benzo[a]phenazines synthesized from 1,2-naphthoquinone, lapachol, beta-lapachone and several derivatives have been tested against…”
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Increasing access to next-generation sequencing in oncology for Brazil
Published in The lancet oncology (01-01-2019)“…The committee do a technical analysis to consider criteria such as clinical effectiveness, budget impact, and availability of infrastructure to perform the…”
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In Vitro—Reduced Susceptibility to Artemether in P. falciparum and Its Association With Polymorphisms on Transporter Genes
Published in The Journal of infectious diseases (01-08-2012)“…Plasmodium falciparum with reduced sensitivity to artemisinin derivatives has been observed in endemic areas, but the molecular mechanisms for this reduced…”
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Genetic and structural analysis of polyomavirus BK T-antigens reveal a higher density of mutations at inter-domain and hexamerization regions, regardless the status of infection
Published in Journal of medical virology (01-08-2015)“…Polyomavirus BK (BKPyV) T‐antigens (large and small tumor antigens, or Lt‐ag and st‐ag, respectively), control key aspects of viral replication and are able to…”
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Detection of merkel cell polyomavirus in oral samples of renal transplant recipients without Merkel cell carcinoma
Published in Journal of medical virology (01-11-2013)“…Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine cancer, with approximately 80% of cases associated with Merkel cell polyomavirus (MCPyV)…”
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Hepatitis C virus genotypes in hemodialysis patients in Angola
Published in Journal of medical virology (01-03-2019)“…To our knowledge, there are no published data on hepatitis C virus (HCV) genotypes in Angola. This study aimed at assessing the distribution of HCV genotypes…”
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Chloroquine and sulphadoxine-pyrimethamine sensitivity of Plasmodium falciparum parasites in a Brazilian endemic area
Published in Malaria journal (14-07-2009)“…The goal of the present study was the characterization of Plasmodium falciparum genes associated to malaria drug resistance (pfcrt, pfdhfr and pfdhps), in…”
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Espectro de Atividade NK em um Pequeno Grupo Populacional Brasileiro
Published in Revista Brasileira de Cancerologia (03-08-2023)“…Um painel de atividade NK nos indivíduos normais de nossa população foi obtido através da realização de 221 ensaios em 40 indivíduos, sendo 26 do sexo…”
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Genetic diversity of chloroquine-resistant Plasmodium vivax parasites from the western Brazilian Amazon
Published in Memórias do Instituto Oswaldo Cruz (01-11-2014)“…The molecular basis of Plasmodium vivax chloroquine (CQ) resistance is still unknown. Elucidating the molecular background of parasites that are sensitive or…”
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