Search Results - "Zaldivar, Mirko Moreno"

The fractalkine receptor CX3CR1 is involved in liver fibrosis due to chronic hepatitis C infection by Wasmuth, Hermann E, Zaldivar, Mirko Moreno, Berres, Marie-Luise, Werth, Alexa, Scholten, David, Hillebrandt, Sonja, Tacke, Frank, Schmitz, Petra, Dahl, Edgar, Wiederholt, Tonio, Hellerbrand, Claus, Berg, Thomas, Weiskirchen, Ralf, Trautwein, Christian, Lammert, Frank

“…Background/Aims The chemokine receptor CX3CR1 and its specific ligand fractalkine (CX3CL1) are known to modulate inflammatory and fibroproliferative diseases…”
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Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice by Berres, Marie-Luise, Koenen, Rory R, Rueland, Anna, Zaldivar, Mirko Moreno, Heinrichs, Daniel, Sahin, Hacer, Schmitz, Petra, Streetz, Konrad L, Berg, Thomas, Gassler, Nikolaus, Weiskirchen, Ralf, Proudfoot, Amanda, Weber, Christian, Trautwein, Christian, Wasmuth, Hermann E

“…Activation of hepatic stellate cells in response to chronic inflammation represents a crucial step in the development of liver fibrosis. However, the molecules…”
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Chemokine Cxcl9 attenuates liver fibrosis‐associated angiogenesis in mice by Sahin, Hacer, Borkham‐Kamphorst, Erawan, Kuppe, Christoph, Zaldivar, Mirko Moreno, Grouls, Christoph, Al‐samman, Muhammad, Nellen, Andreas, Schmitz, Petra, Heinrichs, Daniel, Berres, Marie‐Luise, Doleschel, Dennis, Scholten, David, Weiskirchen, Ralf, Moeller, Marcus J., Kiessling, Fabian, Trautwein, Christian, Wasmuth, Hermann E.

“…Recent data suggest that the chemokine receptor CXCR3 is functionally involved in fibroproliferative disorders, including liver fibrosis. Neoangiogenesis is an…”
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Antifibrotic Effects of CXCL9 and Its Receptor CXCR3 in Livers of Mice and Humans by Wasmuth, Hermann E, Lammert, Frank, Zaldivar, Mirko Moreno, Weiskirchen, Ralf, Hellerbrand, Claus, Scholten, David, Berres, Marie-Luise, Zimmermann, Henning, Streetz, Konrad L, Tacke, Frank, Hillebrandt, Sonja, Schmitz, Petra, Keppeler, Hildegard, Berg, Thomas, Dahl, Edgar, Gassler, Nikolaus, Friedman, Scott L, Trautwein, Christian

“…Background & Aims Fibrosis is the hallmark of chronic liver diseases, yet many aspects of its mechanism remain to be defined. Chemokines are ubiquitous…”
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Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice by Sahin, Hacer, Borkham-Kamphorst, Erawan, Kuppe, Christoph, Zaldivar, Mirko Moreno, Grouls, Christoph, Al-samman, Muhammad, Nellen, Andreas, Schmitz, Petra, Heinrichs, Daniel, Berres, Marie-Luise, Doleschel, Dennis, Scholten, David, Weiskirchen, Ralf, Moeller, Marcus J., Kiessling, Fabian, Trautwein, Christian, Wasmuth, Hermann E.

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The chemokine receptor CXCR3 limits injury after acute toxic liver damage by Zaldivar, Mirko Moreno, Berres, Marie-Luise, Sahin, Hacer, Nellen, Andreas, Heinrichs, Daniel, Schmitz, Petra, Gassler, Nicolaus, Streetz, Konrad L, Trautwein, Christian, Wasmuth, Hermann E

“…Although acute liver failure is a rare disease, its presence is associated with high morbidity and mortality in affected patients. While a contribution of the…”
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The chemokine scavenging receptor D6 limits acute toxic liver injury in vivo by Berres, Marie-Luise, Trautwein, Christian, Zaldivar, Mirko Moreno, Schmitz, Petra, Pauels, Katrin, Lira, Sergio A, Tacke, Frank, Wasmuth, Hermann E

“…The chemokine decoy receptor D6 is a promiscuous chemokine receptor lacking classical signaling functions. It negatively regulates inflammation by targeting CC…”
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CXC chemokine ligand 4 (Cxcl4) is a platelet‐derived mediator of experimental liver fibrosis by Zaldivar, Mirko Moreno, Pauels, Katrin, von Hundelshausen, Philipp, Berres, Marie‐Luise, Schmitz, Petra, Bornemann, Jörg, Kowalska, M. Anna, Gassler, Nikolaus, Streetz, Konrad L., Weiskirchen, Ralf, Trautwein, Christian, Weber, Christian, Wasmuth, Hermann E.

“…Liver fibrosis is a major cause of morbidity and mortality worldwide. Platelets are involved in liver damage, but the underlying molecular mechanisms remain…”
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A functional variation in CHI3L1 is associated with severity of liver fibrosis and YKL-40 serum levels in chronic hepatitis C infection by Berres, Marie-Luise, Papen, Sven, Pauels, Katrin, Schmitz, Petra, Zaldivar, Mirko Moreno, Hellerbrand, Claus, Mueller, Tobias, Berg, Thomas, Weiskirchen, Ralf, Trautwein, Christian, Wasmuth, Hermann E

“…Background/Aims YKL-40 is a chitinase-like protein involved in matrix remodelling and a non-invasive fibrosis marker. We assessed whether a functional promoter…”
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Antagonism of the chemokine Cc15 ameliorates experimental liver fibrosis in mice by Berres, Marie-Luise, Koenen, Rory R, Rueland, Anna, Zaldivar, Mirko Moreno, Heinrichs, Daniel, Sahin, Hacer, Schmitz, Petra, Streetz, Konrad L, Berg, Thomas, Gassler, Nikolaus, Weiskirchen, Ralf, Proudfoot, Amanda, Weber, Christian, Trautwein, Christian, Wasmuth, Hermann E

“…Activation of hepatic stellate cells in response to chronic inflammation represents a crucial step in the development of liver fibrosis. However, the molecules…”
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Genetic variations of the chemokine scavenger receptor D6 are associated with liver inflammation in chronic hepatitis C by Wiederholt, Tonio, von Westernhagen, Michael, Zaldivar, Mirko Moreno, Berres, Marie-Luise, Schmitz, Petra, Hellerbrand, Claus, Müller, Tobias, Berg, Thomas, Trautwein, Christian, Wasmuth, Hermann E

“…Abstract Chronic hepatitis C (HCV) represents one of the most common chronic infections worldwide and is a major indication for liver transplantation. Liver…”
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Of mice and NASH – from fat to inflammation and fibrosis by Wasmuth, Hermann E., Zaldivar, Mirko Moreno, Beraza, Naiara, Trautwein, Christian

“…The pathophysiology of non-alcoholic steatohepatitis (NASH) is complex and modulated by exogenous and genetic factors. Since only minor advances have been made…”
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