Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review

Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review

Pectin is a polymer with a core of alternating -1,4-linked d-galacturonic acid and α-1,2-l-rhamnose units, as well as a variety of neutral sugars such as arabinose, galactose, and lesser amounts of other sugars. Currently, native pectins have been compared to modified ones due to the development of...

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Bibliographic Details
Published in:Polymers Vol. 10; no. 12; p. 1407
Main Authors: Minzanova, Salima T, Mironov, Vladimir F, Arkhipova, Daria M, Khabibullina, Anna V, Mironova, Lubov G, Zakirova, Yulia M, Milyukov, Vasili A
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 19-12-2018
MDPI
Subjects:
Acids
Anticancer properties
Antioxidants
Arabinose
Biological activity
Citrus fruits
drug delivery
Drug delivery systems
Ethanol
Galactose
Immune system
Immunosuppressive agents
modified pectin
Molecular weight
Pectin
pharmaceutical
Pharmacology
Polysaccharides
R&D
Research & development
Review
Sugar
modified pectin
pharmaceutical
biological activity
drug delivery
pectin
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Summary:Pectin is a polymer with a core of alternating -1,4-linked d-galacturonic acid and α-1,2-l-rhamnose units, as well as a variety of neutral sugars such as arabinose, galactose, and lesser amounts of other sugars. Currently, native pectins have been compared to modified ones due to the development of natural medicines and health products. In this review, the results of a study of the bioactivity of pectic polysaccharides, including its various pharmacological applications, such as its immunoregulatory, anti-inflammatory, hypoglycemic, antibacterial, antioxidant and antitumor activities, have been summarized. The potential of pectins to contribute to the enhancement of drug delivery systems has been observed.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:2073-4360
2073-4360
DOI:10.3390/polym10121407