Search Results - "Zakirova, N. F."

Expression of HIV-1 Reverse Transcriptase in Murine Cancer Cells Increases Mitochondrial Respiration by Zakirova, N. F., Kondrashova, A. S., Golikov, M. V., Ivanova, O. N., Ivanov, A. V., Isaguliants, M. G., Bayurova, E. O.

“…— Changes in metabolic pathways are often associated with the development of a wide range of pathologies. Increased glycolysis under conditions of sufficient…”
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A new approach to the synthesis of optically active alkylated adenine derivatives by Zakirova, N.F., Shipitsyn, A.V., Belanov, E.F., Jasko, M.V.

“…A new synthesis of chiral acyclic nucleoside and nucleotide analogues starting from d(−)- or l(+)-riboses was proposed. Antiviral properties of the synthesized…”
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Resistance of THP-1 Leukemia Cells Infected with Cytomegalovirus to Anti-tumor Antibiotic Doxorubicin and Restoration of the Sensitivity by Inhibitors of the PI3K/AKT/mTOR Molecular Pathway by Chernoryzh, Ya. Yu, Fedorova, N. E., Yurlov, K. I., Simonov, R. A., Kornev, A. B., Karpov, D. S., Zakirova, N. F., Ivanov, A. V., Kushch, A. A., Gintsburg, A. L.

“…Results obtained showed that infection with HCMV prevented the death of THP-1 cells treated with DOX in both active and latent forms of infection. In the…”
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Phosphoramidate derivatives of acyclovir, inhibitors of herpes virus replication by Zakirova, N. F., Shipitsyn, A. V., Jasko, M. V., Kochetkov, S. N.

“…A series of new acyclovir phosphoramidates—potential antiviral agents against resistant strains of herpes virus—was synthesized. Of several approaches used for…”
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Hepatitis C virus helicase/NTPase: an efficient expression system and new inhibitors by Mukovnya, A. V., Tunitskaya, V. L., Khandazhinskaya, A. L., Golubeva, N. A., Zakirova, N. F., Ivanov, A. V., Kukhanova, M. K., Kochetkov, S. N.

“…A method has been developed for obtaining a full-length protein NS3 of hepatitis C virus with the yield of 6.5 mg/liter of cell culture, and conditions for…”
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P-(Alkyl)-Nucleoside 5′-Hydrogenphosphonates as Depot Forms of Antiviral Nucleotide Analogues by Khandazhinskaya, A. L., Shirokova, E. A., Karpenko, I. L., Zakirova, N. F., Tarussova, N. B., Krayevsky, A. A.

“…P-(Alkyl)esters of AZT 5′-hydrogenphosphonate were synthesized and their stabilities in the phosphate buffer and human serum were evaluated. The esters bearing…”
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Hypophosphoric acid is a unique substrate of pyrophosphorolysis catalyzed by HIV-1 reverse transcriptase by Kukhanova, Marina K., Zakirova, Natalia F., Ivanov, Alexander V., Alexandrova, Ludmila A., Jasco, Maxim V., Khomutov, Alex R.

“…Pyrophosphate analogues, namely, pyrophosphorous, hypophosphoric, and hypophosphorous acids, were evaluated as inhibitors in elongation reactions and…”
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Lamivudine phosphoramidates. Unexpected products of a well-known reaction by Zakirova, N. F., Shipitsyn, A. V.

“…A series of phosphoramidate derivatives of β-L-2´,3´-dideoxy-3´-thiacytidine (lamivudine, 3TC), which are the latent forms of 3TC monophosphate, were…”
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The synthesis of imidodiphosphoric acid derivatives as potential substrates in the pyrophosphorolysis reaction by Zakirova, N. F., Golubeva, N. A., Shipitsin, A. V., Aleksandrova, L. A.

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The preparation of a photoreactive analogue of 2′,3′-dideoxyuridine 5′-triphosphate and its use for photoaffinity modification of human replication protein A by Kolpashchikov, D. M., Alexandrova, L. A., Zakirova, N. F., Khodyreva, S. N., Lavrik, O. I.

“…A new reagent for photoaffinity modification of biopolymers, 5-[E-N-(2-nitro-5-azidobenzoyl)-3-amino-1-propen-1-yl]-2′,3′-dideoxyuridine 5′-triphosphate…”
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Acyclovir phosphoramidates as potential anti-HIV drugs by Zakirova, N. F., Karpenko, I. L., Prokofjeva, M. M., Vanpouille, C., Prassolov, V. S., Shipitsyn, A. V., Kochetkov, S. N.

“…A number of phosphoramidate derivatives of acyclovir (ACV) were obtained. These compounds revealed themselves as latent forms of acyclovir monophosphate…”
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Phosphoramidate derivatives of acyclovir--herpes virus replication inhibitors by Zakirova, N F, Shipitsyn, A V, Ias'ko, M V, Kochetkov, S N

“…A number of new phosphoramidates of acyclovir--compounds of interest as anti-virals against resistant strains of virus herpes was synthesized. Several methods…”
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The synthesis of imidodiphosphoric acid derivatives as potential substrates in the pyrophosphorolysis reaction by Zakirova, N F, Golubeva, N A, Shipitsin, A V, Aleksandrova

“…The preparation conditions for dichlorophosphinylphosphorimidic trichloride were optimized. It was used in the synthesis of esters of imidodiphosphoric acid…”
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A new approach to the synthesis of optically active alkylated adenine derivatives by ZAKIROVA, N. F, SHIPITSYN, A. V, BELANOV, E. F, JASKO, M. V

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The effect of pyrophosphate analogues on the inorganic pyrophosphatase from Escherichia coli by Zakirova, N F, Ivanov, A V, Skoblov, Iu S, Kukhanova, M K

“…The effect of inorganic pyrophosphate analogues on the enzymic activity of inorganic pyrophosphatase from E. coli was studied. Hypophosphoric and diphosphonic…”
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A photoreactive analogue of 2'3'-dideoxyuridine 5'-triphosphate: preparation and use for photoaffinity modification of human replication protein A by Kolpashchikov, D M, Aleksandrova, L A, Zakirova, N F, Khodyreva, S N, Lavrik, O I

“…A new reagent for photoaffinity modification of biopolymers, 5-[E-N-(2-nitro-5-azidobenzoyl)-3-amino-1-propen-1-yl]-2',3'-dideoxyuridine 5'-triphosphate…”
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Phosphorodiamides as Prodrugs for Antiviral Nucleosides by Shipitsyn, Alexander V., Zakirova, Natalya F., Belanov, Evgeny F., Pronyaeva, Tatyana R., Fedyuk, Nina V., Kukhanova, Marina K., Pokrovsky, Andrey G.

“…New phosphorodiamides of modified nucleoside monophosphates were synthesized and their antiviral properties were evaluated…”
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Quality of water and gas pipe from continuous furnace welding mills by Matveev, Yu. M., Oshchepkov, Yu. P., Zubareva, V. A., Kuznetsov, . M., Zakirova, F. N.

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