Search Results - "Zakin, Mario M"

Antioxidative and Antiatherosclerotic Effects of Human Apolipoprotein A-IV in Apolipoprotein E-Deficient Mice by Ostos, Maria A, Conconi, Mariangela, Vergnes, Laurent, Baroukh, Nadine, Ribalta, Josep, Girona, Josefa, Caillaud, Jean-Michel, Ochoa, Alberto, Zakin, Mario M

“…ABSTRACT—Mice expressing human apolipoprotein A-IV (apoA-IV) mainly in the intestine were obtained in an apolipoprotein E-deficient (apoE0) background…”
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Human apoA‐I/C‐III/A‐IV gene cluster transgenic rabbits: effects of a high‐cholesterol diet by Recalde, Delia, Baroukh, Nadine, Viglietta, Celine, Prince, Sonia, Verona, Julián, Vergnes, Laurent, Pidoux, Josette, Nazeem Nanjee, M, Brites, Fernando, Ochoa, Alberto, Castro, Graciela, Zakin, Mario M, Miller, Norman E, Marie Houdebine, Louis

“…We have generated transgenic rabbits that express the entire human apoA‐I/C‐III/A‐IV gene cluster. As in humans, h‐apoA‐I and h‐apoC‐III were expressed in…”
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Implication of natural killer T cells in atherosclerosis development during a LPS-induced chronic inflammation by Ostos, Maria A, Recalde, Delia, Zakin, Mario M, Scott-Algara, Daniel

“…Atherosclerosis has many features of a chronic inflammatory disease. To evaluate the role of lipopolysaccharide (LPS), mimicking a systemic infection, we…”
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Expression of Human Apolipoprotein A-I/C-III/A-IV Gene Cluster in Mice Induces Hyperlipidemia but Reduces Atherogenesis by Vergnes, Laurent, Baroukh, Nadine, Ostos, Maria A, Castro, Graciela, Duverger, Nicolas, Nanjee, M Nazeem, Najib, Jamila, Fruchart, Jean-Charles, Miller, Norman E, Zakin, Mario M, Ochoa, Alberto

“…The apolipoprotein (apo)A-I/C-III/A-IV gene cluster is involved in lipid metabolism and atherosclerosis. Overexpression of apoC-III in mice causes…”
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Transcriptional Regulation of 5-Aminolevulinate Synthase by Phenobarbital and cAMP-Dependent Protein Kinase by Varone, Cecilia L, Giono, Luciana E, Ochoa, Alberto, Zakin, Mario M, Cánepa, Eduardo T

“…5-Aminolevulinate synthase (ALA-S) is a mitochondrial matrix enzyme that catalyzes the first and rate-limiting step of the heme biosynthesis. There are two…”
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Human Apolipoprotein A-IV Reduces Secretion of Proinflammatory Cytokines and Atherosclerotic Effects of a Chronic Infection Mimicked by Lipopolysaccharide by Recalde, Delia, Ostos, Maria A, Badell, Edgar, Garcia-Otin, Angel-Luis, Pidoux, Josette, Castro, Graciela, Zakin, Mario M, Scott-Algara, Daniel

“…OBJECTIVE—Expression of human apolipoprotein (h-apo) A-IV in apoE-deficient (apoE0) mice (h-apoA-IV/E0) reduces susceptibility to atherosclerosis. Chronic…”
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Expression, purification, and initial structural characterization of rat orphan nuclear receptor NOR-1 LBD domain by Razzera, Guilherme, Vernal, Javier, Portugal, Rodrigo V., Calgaro, Marcos R., Fernandez, Pablo, Zakin, Mario M., Polikarpov, Igor, Terenzi, Hernán

“…NOR-1 is an orphan member of the nuclear receptor superfamily, which includes a group of transcription factors involved in the response to steroids, fatty…”
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Human apolipoprotein A-IV reduces gastric acid secretion and diminishes ulcer formation in transgenic mice by Vergnes, Laurent, Baroukh, Nadine, Léhy, Thérèse, Moizo, Laurent, Bado, André, Baralle, Marco, Baralle, Francisco E, Zakin, Mario M, Ochoa, Alberto

“…We have investigated the involvement of human apolipoprotein A-IV (apoA-IV) in gastric acid secretion and ulcer formation in recently generated apoA-IV…”
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Nuclear Receptors Nor1 and NGFI-B/Nur77 Play Similar, Albeit Distinct, Roles in the Hypothalamo-Pituitary-Adrenal Axis by Fernandez, Pablo M., Brunel, Franck, Jimenez, María Arroyo, Saez, José M., Cereghini, Silvia, Zakin, Mario M.

“…Abstract Studies in Nur77-deficient mice have shown that the basal regulation of hypothalamic and pituitary functions as well as the adrenocortical…”
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The apolipoprotein A-I/C-III/A-IV gene cluster: ApoC-III and ApoA-IV expression is regulated by two common enhancers by Vergnes, Laurent, Taniguchi, Tomoyasu, Omori, Kenji, Zakin, Mario M, Ochoa, Alberto

“…Genetic, epidemiological and clinical evidence have clearly demonstrated the importance of the human apolipoprotein (apo) A-I/C-III/A-IV gene cluster in lipid…”
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Myelination and motor coordination are increased in transferrin transgenic mice by Saleh, Maria-Carla, Espinosa de los Monteros, Araceli, de Arriba Zerpa, Gonzalo A., Fontaine, Isabelle, Piaud, Oriane, Djordjijevic, Dragan, Baroukh, Nadine, Otin, Angel Luis Garcia, Ortiz, Esteban, Lewis, Sandra, Fiette, Laurence, Santambrogio, Paolo, Belzung, Catherine, Connor, James R., de Vellis, Jean, Pasquini, Juana M., Zakin, Mario M., Baron, Bruno, Guillou, Florian

“…Myelin deficiency in the central nervous system (CNS) can cause severe disabling conditions. Most of the transgenic mice models overexpressing myelin…”
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Alternative splicing prevents transferrin secretion during differentiation of a human oligodendrocyte cell line by de Arriba Zerpa, Gonzalo A., Saleh, María-Carla, Fernández, Pablo M., Guillou, Florian, Espinosa de los Monteros, Araceli, de Vellis, Jean, Zakin, Mario M., Baron, Bruno

“…Transferrin, the iron‐transport protein of vertebrate serum, is synthesized mainly in the liver, from which it is secreted into the blood. Transferrin is also…”
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Regulation of the tissue-specific expression of transferrin gene by Zakin, Mario M, Baron, Bruno, Guillou, Florian

“…Transferrin (Tf), the plasma protein involved in iron transport, seems to play complex physiological roles related to cell function, differentiation and…”
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Fructose intake increases hyperlipidemia and modifies apolipoprotein expression in apolipoprotein AI-CIII-AIV transgenic mice by Ostos, Maria A, Recalde, Delia, Baroukh, Nadine, Callejo, Ahinoa, Rouis, Mustapha, Castro, Graciela, Zakin, Mario M

“…Fructose intake has increased steadily during the past two decades. The objective of this study was to determine the effect of fructose intake on lipid…”
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Expression and secretion of human apolipoprotein A-I in the heart by Baroukh, Nadine, Lopez, Camilo E, Saleh, Maria-Carla, Recalde, Delia, Vergnes, Laurent, Ostos, Maria A, Fiette, Laurence, Fruchart, Jean-Charles, Castro, Graciela, Zakin, Mario M, Ochoa, Alberto

“…Various studies have correlated apolipoprotein (apo) A-I, the major component high-density lipoprotein, with protection against development of cardiovascular…”
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Genetics and molecular biology by Recalde, Delia, Zakin, Mario M

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Transcriptional Suppression of the Transferrin Gene by Hypolipidemic Peroxisome Proliferators (∗) by Hertz, Rachel, Seckbach, Mesha, Zakin, Mario M., Bar-Tana, Jacob

“…Activation of gene expression by hypolipidemic peroxisome proliferators (e.g. native and substituted long chain fatty acids, aryloxyalkanoic fibrate drugs) is…”
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Genetics and molecular biology by Garcia-Otin, Angel-Luis, Zakin, Mario M

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Genetics and molecular biology by Ostos, Maria A, Zakin, Mario M

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Solution structure of the orphan nuclear receptor Rev-erb beta response element by H, P NMR and molecular simulation by Castagne, Claire, Terenzi, Hernan, Zakin, Mario M, Delepierre, Muriel

“…Rev-erb beta is an orphan receptor that binds as a homodimer or as a monomer to DNA. The solution structure of the non-palindromic 15 bp DNA duplex…”
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