Search Results - "Zaki, Mohamed H."

Safety and efficacy of pomalidomide plus low-dose dexamethasone in STRATUS (MM-010): a phase 3b study in refractory multiple myeloma by Dimopoulos, Meletios A., Palumbo, Antonio, Corradini, Paolo, Cavo, Michele, Delforge, Michel, Di Raimondo, Francesco, Weisel, Katja C., Oriol, Albert, Hansson, Markus, Vacca, Angelo, Blanchard, María Jesús, Goldschmidt, Hartmut, Doyen, Chantal, Kaiser, Martin, Petrini, Mario, Anttila, Pekka, Cafro, Anna Maria, Raymakers, Reinier, San-Miguel, Jesus, de Arriba, Felipe, Knop, Stefan, Röllig, Christoph, Ocio, Enrique M., Morgan, Gareth, Miller, Neil, Simcock, Mathew, Peluso, Teresa, Herring, Jennifer, Sternas, Lars, Zaki, Mohamed H., Moreau, Philippe

“…Patients with relapsed and/or refractory multiple myeloma (RRMM) have poor prognosis. The STRATUS study assessed safety and efficacy of pomalidomide plus…”
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Dynamic mode decomposition type algorithms for modeling and predicting queue lengths at signalized intersections with short lookback by Shabab, Kazi Redwan, Mustavee, Shakib, Agarwal, Shaurya, Zaki, Mohamed H., Das, Sajal K.

“…This article explores a novel data-driven approach based on recent developments in Koopman operator theory and dynamic mode decomposition (DMD) for modeling…”
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Generative Modeling of Pedestrian Behavior: A Receding Horizon Optimization-Based Trajectory Planning Approach by Gupta, Saumya, Zaki, Mohamed H., Vela, Adan

“…Urbanization is bringing together various modes of transport, and with that, there are challenges to maintaining the safety of all road users, especially…”
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HISS: A Pedestrian Trajectory Planning Framework using Receding Horizon Optimization by Gupta, Saumya, Zaki, Mohamed H., Vela, Adan

“…The paper proposes a generative pedestrian trajectory modeling framework named HISS -Human Interactions in Shared Space. The trajectory modeling framework is…”
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Impact of prior treatment and depth of response on survival in MM-003, a randomized phase 3 study comparing pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone in relapsed/refractory multiple myeloma by San Miguel, Jesus F, Weisel, Katja C, Song, Kevin W, Delforge, Michel, Karlin, Lionel, Goldschmidt, Hartmut, Moreau, Philippe, Banos, Anne, Oriol, Albert, Garderet, Laurent, Cavo, Michele, Ivanova, Valentina, Alegre, Adrian, Martinez-Lopez, Joaquin, Chen, Christine, Renner, Christoph, Bahlis, Nizar Jacques, Yu, Xin, Teasdale, Terri, Sternas, Lars, Jacques, Christian, Zaki, Mohamed H, Dimopoulos, Meletios A

“…Pomalidomide is a distinct oral IMiD(®) immunomodulatory agent with direct antimyeloma, stromal-support inhibitory, and immunomodulatory effects. The pivotal,…”
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Toward the Formalization of Macroscopic Models of Traffic Flow Using Higher-Order-Logic Theorem Proving by Rashid, Adnan, Umair, Muhammad, Hasan, Osman, Zaki, Mohamed H.

“…Next-generation transportation will be integrated, interconnected and highly autonomous. One key challenge in traffic management is ensuring safety while…”
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Inhibition of Interleukin-6 Signaling with CNTO 328 Enhances the Activity of Bortezomib in Preclinical Models of Multiple Myeloma by Voorhees, Peter M, Chen, Qing, Kuhn, Deborah J, Small, George W, Hunsucker, Sally A, Strader, John S, Corringham, Robert E, Zaki, Mohamed H, Nemeth, Jeffrey A, Orlowski, Robert Z

“…Purpose: Inhibition of the proteasome leads to the activation of survival pathways in addition to those that promote cell death. We hypothesized that…”
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Analysis of renal impairment in MM-003, a phase III study of pomalidomide + low - dose dexamethasone versus high - dose dexamethasone in refractory or relapsed and refractory multiple myeloma by Weisel, Katja C, Dimopoulos, Meletios A, Moreau, Philippe, Lacy, Martha Q, Song, Kevin W, Delforge, Michel, Karlin, Lionel, Goldschmidt, Hartmut, Banos, Anne, Oriol, Albert, Alegre, Adrian, Chen, Christine, Cavo, Michele, Garderet, Laurent, Ivanova, Valentina, Martinez-Lopez, Joaquin, Knop, Stefan, Yu, Xin, Hong, Kevin, Sternas, Lars, Jacques, Christian, Zaki, Mohamed H, San Miguel, Jesus

“…Pomalidomide + low-dose dexamethasone is effective and well tolerated for refractory or relapsed and refractory multiple myeloma after bortezomib and…”
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CNTO 328, a monoclonal antibody to IL‐6, inhibits human tumor‐induced cachexia in nude mice by Zaki, Mohamed H., Nemeth, Jeffrey A., Trikha, Mohit

“…IL‐6 is a multifunctional cytokine implicated in several cancers. IL‐6 is a growth factor for certain tumors and contributes to drug resistance, cachexia and…”
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Automated Analysis of Pedestrian Group Behavior in Urban Settings by Zaki, Mohamed H., Sayed, Tarek

“…Movement trajectory of pedestrians, when tracked from video data, enables the automated analysis of individual's walking behavior. For example, speed…”
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Mating Sensitivity Analysis and Statistical Verification for Efficient Yield Estimation by Seghaier, Ibtissem, Zaki, Mohamed H., Tahar, Sofiene

“…Parametric yield is a significant threat to the reliability of nanoscale analog and mixed-signal circuits. A critical yet challenging problem of yield…”
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Cutaneous castleman's disease responds to anti–interleukin-6 treatment by Ahmed, Bilal, Tschen, Jaime A, Cohen, Philip R, Zaki, Mohamed H, Rady, Peter L, Tyring, Stephen K, Corringham, Robert E, Kurzrock, Razelle

“…Castleman's disease is uncommon, and cutaneous involvement is even rarer. We report a 42-year-old Asian woman with the multicentric plasma cell variant of…”
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Pomalidomide alone or in combination with low-dose dexamethasone in relapsed and refractory multiple myeloma: a randomized phase 2 study by Richardson, Paul G., Siegel, David S., Vij, Ravi, Hofmeister, Craig C., Baz, Rachid, Jagannath, Sundar, Chen, Christine, Lonial, Sagar, Jakubowiak, Andrzej, Bahlis, Nizar, Song, Kevin, Belch, Andrew, Raje, Noopur, Shustik, Chaim, Lentzsch, Suzanne, Lacy, Martha, Mikhael, Joseph, Matous, Jeffrey, Vesole, David, Chen, Min, Zaki, Mohamed H., Jacques, Christian, Yu, Zhinuan, Anderson, Kenneth C.

“…This multicenter, open-label, randomized phase 2 study assessed the efficacy and safety of pomalidomide (POM) with/without low-dose dexamethasone (LoDEX) in…”
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Transportation Electrification: A Critical Review of EVs Mobility during Disruptive Events by Torkey, Alaa, Zaki, Mohamed H., El Damatty, Ashraf A.

“…Transportation electrification is a promising emerging technology for mitigating the impacts of climate change. However, it provides more challenges to…”
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Automated safety diagnosis of vehicle–bicycle interactions using computer vision analysis by Sayed, Tarek, Zaki, Mohamed H., Autey, Jarvis

“…•An automated safety diagnosis approach for evaluating vehicle–bicycle conflicts using video analysis is demonstrated.•Traffic conflicts are automatically…”
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Safety evaluation of right-turn smart channels using automated traffic conflict analysis by Autey, Jarvis, Sayed, Tarek, Zaki, Mohamed H.

“…This paper presents the results of a before–after (BA) safety evaluation of a newly proposed design for channelized right-turn lanes. The new design, termed…”
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A framework for automated road-users classification using movement trajectories by Zaki, Mohamed H., Sayed, Tarek

“…•We classify road-users trajectories obtained through automated computer vision.•The classification relies on the motion pattern analysis of each road-user…”
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Use of Drivers’ Jerk Profiles in Computer Vision–Based Traffic Safety Evaluations by Zaki, Mohamed H., Sayed, Tarek, Shaaban, Khaled

“…A traffic conflict is usually composed of a chain of events in which at least one of the involved road users performs some sort of evasive action to avoid a…”
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Exploring Evasive Action–Based Indicators for PTW Conflicts in Shared Traffic Facility Environments by Guo, Yanyong, Sayed, Tarek, Zaki, Mohamed H

“…AbstractSurrogate safety measures such as traffic conflicts are gaining more and more attention for traffic safety analysis. The traffic conflict technique…”
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A Formal Approach to Road Safety Assessment Using Traffic Conflict Techniques by Barhoumi, Oumaima, Zaki, Mohamed H., Tahar, Sofiene

“…Traffic conflict techniques enable a comprehensive assessment of traffic safety analysis. Formal methods allow the identification of factors that contribute to…”
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