Search Results - "Zaki, Hanane"

Computational approaches to discover a Kaempferol derivative extracted from Senna alexandrina as Escherichia coli enzyme (MurF) inhibitor by molecular docking, molecular dynamics simulation, and ADME-Tox by Abdessadak, Oumayma, Alaqarbeh, Marwa, Zaki, Hanane, Almohtaseb, Firas, Alsakhen, Nada, Ajana, Mohammed Aziz, Lakhlifi, Tahar, Bouachrine, Mohammed

“…Escherichia coli is presented in the human intestines as a harmless bacterium, but if it exceeds the normal threshold, it will be pathogenic bacteria causing…”
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Unsymmetrical aromatic disulfides as SARS-CoV-2 Mpro inhibitors: Molecular docking, molecular dynamics, and ADME scoring investigations by Chtita, Samir, Belaidi, Salah, Qais, Faizan Abul, Ouassaf, Mebarka, AlMogren, Muneerah Mogren, Al-Zahrani, Ateyah A., Bakhouch, Mohamed, Belhassan, Assia, Zaki, Hanane, Bouachrine, Mohammed, Lakhlifi, Tahar

“…[Display omitted] COVID-19 pandemic caused by very severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) agent is an ongoing major global health…”
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The anticoagulant potential of Lippia Alba extract in inhibiting SARS-CoV-2 Mpro: Density functional calculation, molecular docking analysis, and molecular dynamics simulations by Yamari, Imane, Abchir, Oussama, Siddique, Farhan, Zaki, Hanane, Errougui, Abdelkbir, Talbi, Mohammed, Bouachrine, Mohammed, ElKouali, M'hammed, Chtita, Samir

“…Lippia Alba, a plant commonly utilized in traditional folk medicine, particularly in Brazil, is renowned for its essential oil possessing anti-inflammatory,…”
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Study of novel triazolo-benzodiazepine analogues as antidepressants targeting by molecular docking and ADMET properties prediction by Belhassan, Assia, Zaki, Hanane, Benlyas, Mohamed, Lakhlifi, Tahar, Bouachrine, Mohammed

“…In this study, we have selected a series of a new family of molecules bearing Triazolo-benzodiazepines, an eleven membered heterocyclic ring has been studied…”
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Catastrophic Collision Between Obesity and COVID-19 Have Evoked the Computational Chemistry for Research in Silico Design of New CaMKKII Inhibitors Against Obesity by Using 3D-QSAR, Molecular Docking, and ADMET by HAJJI, Halima, En-nahli, Fatima, Aanouz, Ilham, Zaki, Hanane, Lakhlifi, Tahar, Ajana, Mohammed Aziz, Bouachrine, Mohammed

“…The purpose of the paper is to discuss the various methods and computational approaches, which are used in computer-aided drug design. For this reason,…”
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Assessment of Groundwater Quality in the Tafilalet Region of Southeastern Morocco Using Water Quality Index by Maryam Azirar, Younes FilaliI Zegzouti, Said Benyoussef, Mourad Arabi, Hanane Zaki, Abdellali Abdaoui, Yassine El Yousfi, Ali Ait Boughrous

“…This study evaluated the suitability of groundwater from primary basins in the Tafilalet area of southeast Morocco for drinking purposes. Water samples were…”
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Catastrophic Collision Between Obesity and COVID-19 Have Evoked the Computational Chemistry for Research in Silico Design of New CaMKKII Inhibitors Against Obesity by Using 3D-QSAR, Molecular Docking, and ADMET by Hajji, Halima, nahli, Fatima En, Aanouz, Ilham, Zaki, Hanane, Lakhlifi, Tahar, Ajana, Mohammed Aziz, Bouachrine, Mohammed

“…The purpose of the paper is to discuss the various methods and computational approaches, which are used in computer-aided drug design. For this reason,…”
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Towards potential inhibitors of COVID-19 main protease Mpro by virtual screening and molecular docking study by Soumia, Moujane, Hanane, Zaki, Benaissa, Moualij, Younes, Filali Zegzouti, Chakib, Alem, Mohammed, Bouachrine, Mohamed, Benlyas

“…The COVID-19 pandemic caused by SARS-CoV-2 has started in December 2019 in Wuhan, China, and become a global health problem. The SARS-COV-2 main protease (M…”
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Assessment of asthma treatment against SARS CoV-2 by using a computer approach by Hajji, Halima, El Khatabi, Khalil, Zaki, Hanane, En-nahli, Fatima, Hajji, Lhossain, Lakhlifi, Tahar, Ajana, Mohammed Aziz, Bouachrine, Mohammed

“…The disease caused by the coronavirus is called COVID-19. The degree of infection varies from one person to another. According to the data collected to date,…”
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In silico detection of potential inhibitors from vitamins and their derivatives compounds against SARS-CoV-2 main protease by using molecular docking, molecular dynamic simulation and ADMET profiling by Belhassan, Assia, Chtita, Samir, Zaki, Hanane, Alaqarbeh, Marwa, Alsakhen, Nada, Almohtaseb, Firas, Lakhlifi, Tahar, Bouachrine, Mohammed

“…•Folacin (Vitamin B9), Riboflavin (Vitamin B2), Phylloquinone oxide (Vitamin K1 oxide) and Ergocalciferol (Vitamin D2) are the structures with the best…”
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Camphor, Artemisinin and Sumac Phytochemicals as inhibitors against COVID-19: Computational approach by Belhassan, Assia, Zaki, Hanane, Chtita, Samir, Alaqarbeh, Marwa, Alsakhen, Nada, Benlyas, Mohamed, Lakhlifi, Tahar, Bouachrine, Mohammed

“…Covid-19 is an emerging infectious disease caused by coronavirus SARS-CoV-2. Due to the rapid rise in deaths resulted from this infection all around the world,…”
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New dehydroabietic acid (DHA) derivatives with anticancer activity against HepG2 cancer cell lines as a potential drug targeting EGFR kinase domain. CoMFA study and virtual ligand-based screening by Zaki, Hanane, Belhassan, Assia, Benlyas, Mohamed, Lakhlifi, Tahar, Bouachrine, Mohammed

“…Liver cancer has become the third type of cancer that causes death; this is why the design of new chemotherapeutic drugs against this disease is a major need…”
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Assessment of effective imidazole derivatives against SARS-CoV-2 main protease through computational approach by Belhassan, Assia, En-nahli, Fatima, Zaki, Hanane, Lakhlifi, Tahar, Bouachrine, Mohammed

“…Because of the fast increase in deaths due to Corona Viral Infection in majority region in the world, the detection of drugs potent of this infection is a…”
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Molecular docking of potential cytotoxic alkylating carmustine derivatives 2-chloroethylnitrososulfamides analogues of 2-chloroethylnitrosoureas by Soudani, Wafa, Hadjadj-Aoul, Fatima Zohra, Bouachrine, Mohammed, Zaki, Hanane

“…The objective of this work was the molecular modelling by bio-isostery of 2-chloroethylnitrosoureas CENU into 2-chloroethylnitrososulfamides CENS derived from…”
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Inhibition of the Janus kinase protein (JAK1) by the A. Pyrethrum Root Extract for the treatment of Vitiligo pathology. Design, Molecular Docking, ADME-Tox, MD Simulation, and in-silico investigation by Ouabane, Mohamed, Zaki, Khadija, Zaki, Hanane, Guendouzi, Abdelkrim, Sbai, Abdelouahid, Sekkate, Chakib, Lakhlifi, Tahar, Bouachrine, Mohammed

“…This study delves into the therapeutic efficacy of A. pyrethrum in addressing vitiligo, a chronic inflammatory disorder known for inducing psychological…”
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Molecular Docking, Drug likeness Studies and ADMET prediction of Flavonoids as Platelet-Activating Factor (PAF) Receptor Binding by Mohammed BOUACHRINE, Larbi Elmchichi, Abdellah El Aissouq, Assia BELHASSAN, Hanane Zaki, Abdelkrim Ouammou, Tahar Lakhlifi

“…Studies and scientific research indicate that the platelet-activating factor (PAF) is a major pro-inflammatory mediator in the initiation and development of…”
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Computational Prediction of 3,5-Diaryl-1H-Pyrazole and spiropyrazolines derivatives as potential acetylcholinesterase inhibitors for alzheimer disease treatment by 3D-QSAR, molecular docking, molecular dynamics simulation, and ADME-Tox by El Alaouy, Moulay Ahfid, Alaqarbeh, Marwa, Ouabane, Mohamed, Zaki, Hanane, ElBouhi, Mohamed, Badaoui, Hassan, Moukhliss, Youness, Sbai, Abdelouahid, Maghat, Hamid, Lakhlifi, Tahar, Bouachrine, Mohammed

“…The efficacy of 40 synthesized variants of 3,5-diaryl-1H-pyrazole and spiropyrazoline' derivatives as acetylcholinesterase inhibitors is verified using a…”
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Molecular docking investigation of cytotoxic phenanthrene derivatives by Guédouar, Habiba, Zaki, Hanane, Bouachrine, Mohammed, Aloui, Faouzi

“…Our previous experimental work indicated that the presence of ester functionality in phenanthrene derivatives D-1 and D-2 leads to potent cytotoxicity against…”
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Molecular docking analysis of N-substituted oseltamivir derivatives with the SARS-Cov-2 main protease by Belhassan, Assia, Chtita, Samir, Zaki, Hanane, Lakhlifi, Tahar, Bouachrine, Mohammed

“…The identification of chemotherapeutic drugs against Novel Coronavirus (2019-nCoV) is a significant requirement due to the rapid rise in deaths due to Corona…”
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Discover the Medication Potential of Algerian Medicinal Plants Against Sars-Cov-2 Main Protease (Mpro): Molecular Docking, Molecular Dynamic Simulation, and ADMET Analysis by Soudani, Wafa, Zaki, Hanane, Alaqarbeh, Marwa, ELMchichi, Larbi, Bouachrine, Mohammed, Hadjadj-Aoul, Fatima Zohra

“…At the end of 2019, the world faced a big challenge and crisis caused by the SARS-CoV-2 virus. It spreads rapidly and is contagious; no treatment has…”
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