Search Results - "Zakhem, Elie"

Successful implantation of an engineered tubular neuromuscular tissue composed of human cells and chitosan scaffold by Zakhem, Elie, MS, Elbahrawy, Mostafa, MD, Orlando, Giuseppe, MD, PhD, Bitar, Khalil N., PhD, AGAF

“…Background There is an urgent need for gut lengthening secondary to massive resections of the gastrointestinal tract. In this study, we propose to evaluate the…”
Get full text

Development of Chitosan Scaffolds with Enhanced Mechanical Properties for Intestinal Tissue Engineering Applications by Zakhem, Elie, Bitar, Khalil N

“…Massive resections of segments of the gastrointestinal (GI) tract lead to intestinal discontinuity. Functional tubular replacements are needed. Different…”
Get full text

The Appendix as a Viable Source of Neural Progenitor Cells to Functionally Innervate Bioengineered Gastrointestinal Smooth Muscle Tissues by Zakhem, Elie, Rego, Stephen L., Raghavan, Shreya, Bitar, Khalil N.

“…This study demonstrates the ability of neural stem cells isolated from the appendix to differentiate into mature functional enteric neurons. The…”
Get full text

Design Strategies of Biodegradable Scaffolds for Tissue Regeneration by Bitar, Khalil N., Zakhem, Elie

“…There are numerous available biodegradable materials that can be used as scaffolds in regenerative medicine. Currently, there is a huge emphasis on the…”
Get full text

Bioengineering the gut: future prospects of regenerative medicine by Bitar, Khalil N., Zakhem, Elie

“…Key Points The most common complications of surgical treatments for gastrointestinal disorders include stenosis or leakage; tissue engineering and regenerative…”
Get full text

Sa1629 - Shelf Life of Engineered Autologous Biosphincters for Treatment of Fecal Incontinence by Dadhich, Prabhash, Zakhem, Elie, Bitar, Khalil N.

Get full text

Chitosan-based scaffolds for the support of smooth muscle constructs in intestinal tissue engineering by Zakhem, Elie, Raghavan, Shreya, Gilmont, Robert R, Bitar, Khalil N

“…Abstract Intestinal tissue engineering is an emerging field due to a growing demand for intestinal lengthening and replacement procedures secondary to massive…”
Get full text

Tissue Engineering in the Gut: Developments in Neuromusculature by Bitar, Khalil N, Raghavan, Shreya, Zakhem, Elie

“…The complexity of the gastrointestinal (GI) tract lies in its anatomy as well as in its physiology. Several different cell types populate the GI tract, adding…”
Get full text

147 - Cell Therapy Using Co-Injection of Neural-Progenitor Cells and Interstitial Cells of Cajal to Reinstate Function in an Ex Vivo Model of Neuromuscular Dysfunction of the Pylorus by Dadhich, Prabhash, Zakhem, Elie, Koch, Kenneth L., Bitar, Khalil N.

Get full text

Neo-innervation of a bioengineered intestinal smooth muscle construct around chitosan scaffold by Zakhem, Elie, Raghavan, Shreya, Bitar, Khalil N

“…Abstract Neuromuscular disorders of the gut result in disturbances in gastrointestinal transit. The objective of this study was to evaluate the neo-innervation…”
Get full text

1100 - Successful Transplantation of a Tissue Engineered Human Bowel (TEB) in a Athymic Rat Model by Zakhem, Elie, Tamburrini, Riccardo, Orlando, Giuseppe, Bitar, Khalil N.

Get full text

Shelf Life of Engineered Autologous Biosphincters for Treatment of Fecal Incontinence by Dadhich, Prabhash, Zakhem, Elie, Bitar, Khalil N

Get full text

Tu1763 A Comparison Study of Muscle Progenitor Cells and Mesenchymal Stem Cells Injection in an Unrepaired Injury Model of External Anal Sphincter by Elbahrawy, Mostafa, Zakhem, Elie, Bitar, Khalil N

Get full text

Bioengineering and regeneration of gastrointestinal tissue: where are we now and what comes next? by Zakhem, Elie, Raghavan, Shreya, Suhar, Riley A, Bitar, Khalil N

“…The field of tissue engineering and regenerative medicine has been applied to the gastrointestinal (GI) tract for a couple decades. Several achievements have…”
Get more information

Sa1666 – Integration of Smooth Muscle and Neural Progenitor Cells As Part of Implanted Biosphincters for Treatment of Fecal Incontinence by Dadhich, Prabhash, Bohl, Jaime L., Tamburrini, Riccardo, Zakhem, Elie, Cline, J Mark, Mitchell, Erin, Bitar, Khalil N.

Get full text

Sa1365 Successful Implantation of a Tissue Engineered Gut (TEG) Using Human Smooth Muscle and Human Enteric Neural Progenitor Cell by Zakhem, Elie, Elbahrawy, Mostafa, Bitar, Khalil N

Get full text

Bioengineering functional human sphincteric and non-sphincteric gastrointestinal smooth muscle constructs by Rego, Stephen L., Zakhem, Elie, Orlando, Giuseppe, Bitar, Khalil N.

“…•Bioengineering human pylorus and small intestine smooth muscle constructs.•Constructs exhibit contractile phenotypes and respond to physiologic…”
Get full text

Successful Transplantation of a Tissue Engineered Human Bowel (TEB) in a Athymic Rat Model by Zakhem, Elie, Tamburrini, Riccardo, Orlando, Giuseppe, Bitar, Khalil N

Get full text

997 - Long Term Restoration of Fecal Continence in a Large Animal Model Using Biosphincters by Tamburrini, Riccardo, Bohl, Jaime L., Zakhem, Elie, Dadhich, Prabhash, Scott, Christie L., Mitchell, Erin, Cline, Mark, Bitar, Khalil N.

Get full text

Successful Transplantation of a Human Tissue Engineered Bowel (hTEB) in an Athymic Rat Model by Zakhem, Elie, Tamburrini, Riccardo, Orlando, Giuseppe, Koch, Kenneth L., Bitar, Khalil N.

Get full text