Search Results - "Zakharova, O"

Current Linguistic Situation in Village of Sebyan-Kyuyol in Kobyai District of Republic of Sakha (Yakutia) by Zakharova, L. O.

“…This paper examines the linguistic situation in the village of Sebyan-Kyuyol in the Kobyai district of the Republic of Sakha (Yakutia), where the Lamunkhin…”
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Dual PTP1B/TC-PTP Inhibitors: Biological Evaluation of 3-(Hydroxymethyl)cinnoline-4( 1H )-Ones by Derkach, Kira V, Gureev, Maxim A, Babushkina, Anastasia A, Mikhaylov, Vladimir N, Zakharova, Irina O, Bakhtyukov, Andrey A, Sorokoumov, Viktor N, Novikov, Alexander S, Krasavin, Mikhail, Shpakov, Alexander O, Balova, Irina A

“…Dual inhibitors of protein phosphotyrosine phosphatase 1B (PTP1B)/T-cell protein phosphotyrosine phosphatase (TC-PTP) based on the…”
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Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models by Zakharenko, A.L., Luzina, O.A., Sokolov, D.N., Kaledin, V.I., Nikolin, V.P., Popova, N.A., Patel, J., Zakharova, O.D., Chepanova, A.A., Zafar, A., Reynisson, J., Leung, E., Leung, I.K.H., Volcho, K.P., Salakhutdinov, N.F., Lavrik, O.I.

“…The druggability of the tyrosyl-DNA phosphodiesterase 1 (Tdp1) enzyme was investigated in conjunction with topoisomerase 1 inhibition. A novel class of…”
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The Effects of Separate and Combined Treatment of Male Rats with Type 2 Diabetes with Metformin and Orthosteric and Allosteric Agonists of Luteinizing Hormone Receptor on Steroidogenesis and Spermatogenesis by Bakhtyukov, Andrey A, Derkach, Kira V, Sorokoumov, Viktor N, Stepochkina, Anna M, Romanova, Irina V, Morina, Irina Yu, Zakharova, Irina O, Bayunova, Liubov V, Shpakov, Alexander O

“…In men with type 2 diabetes mellitus (T2DM), steroidogenesis and spermatogenesis are impaired. Metformin and the agonists of luteinizing hormone/human…”
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Neural Network Modeling of Electromagnetic Prediction of Geothermal Reservoir Properties by Spichak, V. V., Zakharova, O. K.

“…—This work conducts neural network modeling of temperature, thermal conductivity, and permeability predictions for depths greater than those drilled, as well…”
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Mitochondrial Electron Transport Chain in Heavy Metal-Induced Neurotoxicity : Effects of Cadmium, Mercury, and Copper by Zakharova, Irina O., Emelyanova, Larisa V., Sokolova, Tatyana V., Belyaeva, Elena A.

“…To clarify the role of mitochondrial electron transport chain (mtETC) in heavy-metal-induced neurotoxicity, we studied action of Cd2+, Hg2+, and Cu2+ on cell…”
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Metal-Based Nanoparticles for the Diagnostics, Therapy, and Prevention of Viral Infections by Zakharova, O V, Vasyukova, I A, Gusev, A A

“…Viral infections are responsible for the death of several million people every year and cause significant damage to the global economy. Existing methods for…”
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Insulin and α-Tocopherol Enhance the Protective Effect of Each Other on Brain Cortical Neurons under Oxidative Stress Conditions and in Rat Two-Vessel Forebrain Ischemia/Reperfusion Injury by Zakharova, Irina O, Bayunova, Liubov V, Zorina, Inna I, Sokolova, Tatiana V, Shpakov, Alexander O, Avrova, Natalia F

“…Clinical trials show that insulin administered intranasally is a promising drug to treat neurodegenerative diseases, but at high doses its use may result in…”
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The Protective Effect of Insulin on Rat Cortical Neurons in Oxidative Stress and Its Dependence on the Modulation of Akt, GSK-3beta, ERK1/2, and AMPK Activities by Zakharova, Irina O, Sokolova, Tatiana V, Bayunova, Liubov V, Zorina, Inna I, Rychkova, Maria P, Shpakov, Alexander O, Avrova, Natalia F

“…Insulin is a promising drug for the treatment of diseases associated with brain damage. However, the mechanism of its neuroprotective action is far from being…”
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The Autophagic and Apoptotic Death of Forebrain Neurons of Rats with Global Brain Ischemia Is Diminished by the Intranasal Administration of Insulin: Possible Mechanism of Its Action by Zakharova, Irina O, Bayunova, Liubov V, Avrova, Daria K, Tretyakova, Alina D, Shpakov, Alexander O, Avrova, Natalia F

“…Insulin is a promising neuroprotector. To better understand the mechanism of insulin action, it was important to show its ability to diminish autophagic…”
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The Influence of Bacterial Mutualists and Phytopatogenes on Changes in the Concentrations of cAMP and H2O2 in Pea Seedless of the Rondo Varieties and its Anodulating and Supernodulating Mutants by Lomovatskaya, L. A., Zakharova, O. V., Goncharova, A. M., Romanenko, A. S.

“…Changes in the concentrations of hydrogen peroxide and cyclic adenosine monophosphate (cAMP) in the roots of seedlings of pea cv. Rondo and its supernodulating…”
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Photocatalytically Active Zinc Oxide and Titanium Dioxide Nanoparticles in Clonal Micropropagation of Plants: Prospects by Zakharova, O. V., Gusev, A. A.

“…— The search for effective and nontoxic sterilization drugs for plants against common phytopathogenic microorganisms is a major challenge to improve the…”
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The Effect of Intranasal Administration of Gangliosides on the Viability of CA1 Hippocampal Neurons in Rat Two-Vessel Occlusion Model of Forebrain Ischemia/Reperfusion Injury by Avrova, D. K., Bayunova, L. V., Avrova, N. F., Zakharova, I. O.

“…Intranasal administration of total bovine brain gangliosides (6 mg/kg) to rats protected the CA1 hippocampal neurons from the death caused by two-vessel…”
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Modern terminology of management: Anglicisms as a means of adaptation to new economic realities by Zakharova, I. O.

“…The subject of this study is an important part of the latest terminology of the modern management sphere, namely, anglicisms. The purpose of the article is to…”
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Spatial Variations of Aftershock Parameters and their Relation to Geodetic Slip Models for the 2010 Mw8.8 Maule and the 2011 Mw9.0 Tohoku-oki Earthquakes by Zakharova, O., Hainzl, S., Lange, D., Enescu, B.

“…Recent development in analysis tools and deployments of the geodetic and seismic instruments give an opportunity to investigate aftershock sequences at local…”
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α-Tocopherol at Nanomolar Concentration Protects Cortical Neurons against Oxidative Stress by Zakharova, Irina O, Sokolova, Tatiana V, Vlasova, Yulia A, Bayunova, Liubov V, Rychkova, Maria P, Avrova, Natalia F

“…The aim of the present work is to study the mechanism of the α-tocopherol (α-T) protective action at nanomolar and micromolar concentrations against…”
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Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening by Mamontova, E.M., Zakharenko, A.L., Zakharova, O.D., Dyrkheeva, N.S., Volcho, K.P., Reynisson, J., Arabshahi, H.J., Salakhutdinov, N.F., Lavrik, O.I.

“…Chemical structure of the dicoumarine compound 5, the most active against SCAN1 and TDP1 (left). Predicted hydrogen bonding interactions of 5 with His263,…”
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Antibiotic Resistance: Modern Approaches and Ways to Overcome It (Review) by Mikhaleva, T. V., Zakharova, O. I., Ilyasov, P. V.

“…The review presents data on the mechanisms of the emergence and development of antibiotic resistance of microorganisms. Modern approaches and ways to overcome…”
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Scanning Nanoindentation as an Instrument of Studying Local Mechanical Properties Distribution in Wood and a New Technique for Dendrochronology by Golovin, Yu. I., Tyurin, A. I., Gusev, A. A., Matveev, S. M., Golovin, D. Yu, Samodurov, A. A., Vasyukova, I. A., Yunak, M. A., Kolesnikov, E. A., Zakharova, O. V.

“…The paper presents the results of scanning of mechanical properties of coniferous (common pine Pinus sylvestris ) and deciduous (small-leaved lime Tilia…”
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The Study of Biological Activity of a New Thieno[2,3-D]-Pyrimidine-Based Neutral Antagonist of Thyrotropin Receptor by Derkach, K. V., Fokina, E. A., Bakhtyukov, A. A., Sorokoumov, V. N., Stepochkina, A. M., Zakharova, I. O., Shpakov, A. O.

“…The development of low-molecular-weight antagonists of thyroid-stimulating hormone (TSH) receptor is a promising trend in the treatment of autoimmune…”
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