Search Results - "Zakharova, I O"
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The Effect of Intranasal Administration of Gangliosides on the Viability of CA1 Hippocampal Neurons in Rat Two-Vessel Occlusion Model of Forebrain Ischemia/Reperfusion Injury
Published in Bulletin of experimental biology and medicine (01-04-2024)“…Intranasal administration of total bovine brain gangliosides (6 mg/kg) to rats protected the CA1 hippocampal neurons from the death caused by two-vessel…”
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The Study of Biological Activity of a New Thieno[2,3-D]-Pyrimidine-Based Neutral Antagonist of Thyrotropin Receptor
Published in Bulletin of experimental biology and medicine (01-04-2022)“…The development of low-molecular-weight antagonists of thyroid-stimulating hormone (TSH) receptor is a promising trend in the treatment of autoimmune…”
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Modern terminology of management: Anglicisms as a means of adaptation to new economic realities
Published in Вестник университета (20-09-2023)“…The subject of this study is an important part of the latest terminology of the modern management sphere, namely, anglicisms. The purpose of the article is to…”
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Neuroprotective Effect of Insulin on Rat Cortical Neurons in Oxidative Stress Is Mediated by Autophagy and Apoptosis Inhibition in vitro
Published in Journal of evolutionary biochemistry and physiology (01-09-2023)“…Although insulin is one of the most promising neuroprotectors, it is still unknown whether it is able to prevent autophagic neuronal cell death. In this work,…”
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Intranasal Insulin Administration to Rats with Forebrain Ischemia and Reperfusion Injury Reduces Autophagy and Apoptosis Intensity in the Hippocampus and Frontal Cortex, a Possible Mechanism of Action
Published in Journal of evolutionary biochemistry and physiology (2024)“…Rat forebrain ischemia followed by a 3-day reperfusion led to an increase in the levels of the autophagic marker LC3B-II and glial fibrillary acidic protein…”
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Antibiotic Resistance: Modern Approaches and Ways to Overcome It (Review)
Published in Applied biochemistry and microbiology (01-03-2019)“…The review presents data on the mechanisms of the emergence and development of antibiotic resistance of microorganisms. Modern approaches and ways to overcome…”
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Intranasal Insulin and Gangliosides Correct Cognitive Impairments and Signaling Pathways in the Hippocampus of Rats with Type 2 Diabetes Mellitus
Published in Journal of evolutionary biochemistry and physiology (01-11-2023)“…Insulin controls both systemic glucose homeostasis and functional brain activity. In type 2 diabetes mellitus (DM2), insulin content and the activity of the…”
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Epizootic situation for brucellosis in the Russian Federation (review)
Published in Agrarnai͡a︡ nauka Evro-Severo-Vostoka (22-02-2023)“…The World Health Organization (WHO) considers brucellosis to be one of the most dangerous and spread zoonosis in the world. The aim of the review is to…”
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Risk factors for African swine fever spread in wild boar in the Russian Federation
Published in Veterinarii︠a︡ segodni︠a︡ = Veterinary science today (15-03-2024)“…The analysis and assessment of risk factors associated with the occurrence, spread and persistence of African swine fever (ASF) virus in wild boar population…”
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Distribution of the Muskrat (Ondatra zibethicus L.) and the American Mink (Neovison vison Schreber) in Yakutia (Northeast Asia, Russia)
Published in Russian journal of biological invasions (01-09-2023)“…This paper discusses the results of the introduction of the muskrat and American mink in Yakutia (Russia). The time course of harvesting of muskrat skins…”
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Intranasal Insulin Decreases Autophagic and Apoptotic Death of Neurons in the Rat Hippocampal C1 Region and Frontal Cortex under Forebrain Ischemia–Reperfusion
Published in Journal of evolutionary biochemistry and physiology (2023)“…The development of approaches to therapy of ischemic brain injuries requires a better insight into the mechanisms that regulate both apoptotic and autophagic…”
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Protective and Antioxidant Effects of Insulin on Rat Brain Cortical Neurons in an in vitro Model of Oxygen and Glucose Deprivation
Published in Journal of evolutionary biochemistry and physiology (2023)“…Insulin is one of the most promising protectors in the treatment of neurodegenerative and other diseases associated with brain injuries. In these diseases,…”
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Effects of Intranasally Administered Insulin and Gangliosides on Metabolic Parameters and Activity of the Hepatic Insulin System in Rats with Type 2 Diabetes Mellitus
Published in Journal of evolutionary biochemistry and physiology (01-03-2022)“…Insulin regulates glucose metabolism via both direct hormone interactions with its signaling system and glucose transporters in cells of peripheral tissues and…”
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Insulin and Brain Gangliosides Prevent Metabolic Disorders Caused by Activation of Free Radical Reactions after Two-Vessel Ischemia–Reperfusion Injury to the Rat Forebrain
Published in Journal of evolutionary biochemistry and physiology (2022)“…The ability of insulin and gangliosides, administered separately or jointly, to increase the viability of cultured brain cortical neurons under conditions of…”
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Intranasal Administration of Insulin and Gangliosides Improves Spatial Memory in Rats with Neonatal Type 2 Diabetes Mellitus
Published in Bulletin of experimental biology and medicine (2020)“…We analyzed the effects of intranasal administration of insulin (0.48 U/rat) and gangliosides (6 mg/kg) on spatial memory in rats with the neonatal model of…”
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Highly pathogenic avian influenza in the world: vaccination strategies (review)
Published in Agrarnai͡a︡ nauka Evro-Severo-Vostoka (23-06-2022)“…Avian influenza viruses are epidemiologically dangerous zoonotic pathogens that can cause high morbidity and mortality both in animals and in humans…”
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Effects of Intranasally Administered Insulin and Gangliosides on Hypothalamic Signaling and Expression of Hepatic Gluconeogenesis Genes in Rats with Type 2 Diabetes Mellitus
Published in Journal of evolutionary biochemistry and physiology (01-11-2022)“…The insulin signaling system in hypothalamic neurons plays an important role in the central regulation of glucose metabolism, feeding behavior, and tissue…”
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Malignant catarrhal fever: pathogenesis, problems of prevention and control (review)
Published in Agrarnai͡a︡ nauka Evro-Severo-Vostoka (28-02-2024)“…Malignant catarrhal fever is a non-contagious infectious disease that occurs sporadically in the population of cattle and wild artiodactyls. The source of the…”
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Foot and mouth disease: risk factors and control measures (review)
Published in Agrarnai͡a︡ nauka Evro-Severo-Vostoka (28-06-2023)“…Foot-and-mouth disease (FMD) is classified by the World Organization for Animal Health (OIE) as a Schedule A disease. Given the potential for rapid spread of…”
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