Search Results - "Zakharova, Anastasiia A"
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Chromone-Containing Allylmorpholines Influence Ion Channels in Lipid Membranes via Dipole Potential and Packing Stress
Published in International journal of molecular sciences (30-09-2022)“…Herein, we report that chromone-containing allylmorpholines can affect ion channels formed by pore-forming antibiotics in model lipid membranes, which…”
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Enhancing the Antimicrobial Properties of Peptides through Cell-Penetrating Peptide Conjugation: A Comprehensive Assessment
Published in International journal of molecular sciences (01-12-2023)“…Combining antimicrobial peptides (AMPs) with cell-penetrating peptides (CPPs) has shown promise in boosting antimicrobial potency, especially against…”
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Optimizing Antimicrobial Peptide Design: Integration of Cell-Penetrating Peptides, Amyloidogenic Fragments, and Amino Acid Residue Modifications
Published in International journal of molecular sciences (01-06-2024)“…The escalating threat of multidrug-resistant pathogens necessitates innovative approaches to combat infectious diseases. In this study, we examined peptides…”
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Lipid Microenvironment Modulates the Pore-Forming Ability of Polymyxin B
Published in Antibiotics (Basel) (20-10-2022)“…The ability of polymyxin B, an antibiotic used to treat infections caused by multidrug-resistant Gram-negative bacteria as a last-line therapeutic option, to…”
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Phosphodiesterase Type 5 Inhibitors Greatly Affect Physicochemical Properties of Model Lipid Membranes
Published in Membranes (Basel) (19-11-2021)“…Although phosphodiesterase type 5 inhibitors are widely used and well-studied drugs, the potential benefits of their application in the treatment of various…”
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Alkaloids Modulate the Functioning of Ion Channels Produced by Antimicrobial Agents via an Influence on the Lipid Host
Published in Frontiers in cell and developmental biology (30-06-2020)“…It is widely recognized that an alteration in membrane physical properties induced by the adsorption of various drugs and biologically active compounds might…”
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Local Anesthetics Affect Gramicidin A Channels via Membrane Electrostatic Potentials
Published in The Journal of membrane biology (01-12-2016)“…The effects of local anesthetics (LAs), including aminoamides and aminoesters, on the characteristics of single gramicidin A (GA) channels in 1,2-dioleoyl- sn…”
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Two types of syringomycin E channels in sphingomyelin-containing bilayers
Published in European biophysics journal (01-01-2016)“…The influence of dipole modifiers on the characteristics of single syringomycin E (SRE) channels in bilayers comprising DOPS, DOPE, sphingolipids…”
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1,3-Thiazine, 1,2,3,4-Dithiadiazole, and Thiohydrazide Derivatives Affect Lipid Bilayer Properties and Ion-Permeable Pores Induced by Antifungals
Published in Frontiers in cell and developmental biology (30-06-2020)“…Over the past decade, thiazines, thiadiazoles, and thiohydrazides have attracted increasing attention due to their sedative, antimicrobial, antiviral,…”
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Fengycin induces ion channels in lipid bilayers mimicking target fungal cell membranes
Published in Scientific reports (05-11-2019)“…The one-sided addition of fengycin (FE) to planar lipid bilayers mimicking target fungal cell membranes up to 0.1 to 0.5 μM in the membrane bathing solution…”
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Ion Channels Induced by Antimicrobial Agents in Model Lipid Membranes are Modulated by Plant Polyphenols Through Surrounding Lipid Media
Published in The Journal of membrane biology (01-08-2018)“…The potential therapeutic applications of plant polyphenols in various neurological, cardiovascular, metabolic and malignant disorders determine the relevance…”
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Lipid-mediated regulation of pore-forming activity of syringomycin E by thyroid hormones and xanthene dyes
Published in Biochimica et biophysica acta. Biomembranes (01-03-2018)“…The effects of dipole modifiers, thyroid hormones (thyroxine and triiodothyronine) and xanthene dyes (Rose Bengal, phloxineB, erythrosin, eosinY and…”
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Blocking ion channels induced by antifungal lipopeptide syringomycin E with amide-linked local anesthetics
Published in Scientific reports (01-08-2018)“…The effects of the amide-linked (lidocaine (LDC), mepivacaine (MPV), prilocaine (PLC)) and ester-bound local anesthetics (benzocaine (BZC), procaine (PRC), and…”
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The Mechanisms of Lipid-Mediated Regulation of the Activity of Antimicrobial Peptides of Different Secondary Structure
Published in Biophysical journal (12-02-2021)Get full text
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Role of Lipid Environment in the Pore-Forming Activity of Cecropin A
Published in Biophysical journal (07-02-2020)Get full text
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Sildenafil and Tadalafil Affect Ion Channels Formed by Antimicrobial Peptides via Membrane Dipole Potential
Published in Biophysical journal (02-02-2018)Get full text
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